TYK Medicines, Inc — Proxy Solicitation & Information Statement 2025

Oct 14, 2025

同源康醫藥

TYK medicines

TYK Medicines, Inc

浙江同源康醫藥股份有限公司

(a joint stock company incorporated in the People's Republic of China with limited liability)

(Stock Code: 2410)

FORM OF PROXY FOR THE SECOND EXTRAORDINARY GENERAL MEETING OF 2025 TO BE HELD ON THURSDAY, OCTOBER 30, 2025 AND ANY ADJOURNMENT THEREOF

I/We $^{(note 1)}$

of $^{(note 1)}$

being the registered holder(s) of $^{(note 2)}$. H shares of RMB1.00 each in the share capital of TYK Medicines, Inc (浙江同源康醫藥股份有限公司) (the "Company"), HEREBY APPOINT THE CHAIRMAN OF THE MEETING $^{(note 3)}$ or

of

to act as my/our proxy to attend and act for me/us at the second extraordinary general meeting of 2025 of the Company (the "Meeting") to be held at 8th Floor, Building T2, China Eastern Binjiang Center, No. 277 Longlan Road, Xuhui District, Shanghai, the PRC at 1:30 p.m. on Thursday, October 30, 2025 and any adjourned meeting thereof, for the purposes of considering and, if thought fit, passing the resolutions $^{(note 4)}$ as set out in the notice convening the Meeting and to vote for me/us and in my/our name(s) in respect of the resolutions as indicated below at the Meeting (and at any adjourned meeting thereof).

ORDINARY RESOLUTIONS^{(Note 4)}		FOR^{(Note 5)}	AGAINST^{(Note 5)}	ABSTAIN^{(Note 5)}
1.	To consider and approve the proposed amendments to the Rules of Procedure for the Board of Directors.
2.	To consider and approve the proposed amendments to the Rules of Procedure for Shareholders’ General Meetings.
SPECIAL RESOLUTIONS^{(Note 4)}		FOR^{(Note 5)}	AGAINST^{(Note 5)}	ABSTAIN^{(Note 5)}
3.	To consider and approve the proposed amendments to the Articles of Association and the proposed abolishment of the Board of Supervisors.
4.	To consider and approve the proposed adoption of the 2025 H Share Incentive Scheme.

Date: _________

Signature(s): _________

Notes:

1. Full name(s) (in Chinese and English, as registered in the register of members of H shares) and registered address(es) to be inserted in BLOCK CAPITALS.
2. Please insert the number of H shares of the Company registered under your name(s) to which this form of proxy relates. If no number is inserted, this form of proxy will be deemed to relate to all H shares of the Company registered in your name(s).
3. If any proxy other than the chairman of the Meeting is appointed, please strike out the words "THE CHAIRMAN OF THE MEETING or" and insert the name and address of the proxy desired in the space provided. A shareholder may appoint one or more proxies to attend and vote on his behalf. If a shareholder appoints more than one proxy, his proxies may only exercise voting rights at a poll. ANY ALTERATION MADE TO THIS FORM OF PROXY MUST BE INITIALLED BY THE PERSON WHO SIGNS IT.
4. The full text of the resolution is set out in the circular of the Meeting dated October 14, 2025, together with which this form of proxy will be published on the websites of the The Stock Exchange of Hong Kong Limited (www.hkexnews.hk) and the Company (www.tykmedicines.com) and sent to shareholders of the Company if requested. Any shareholder who wishes to appoint a proxy shall refer to the Meeting circular.
5. IMPORTANT: IF YOU WISH TO VOTE FOR THE RESOLUTION, PLEASE TICK THE BOX MARKED "FOR" BESIDE THE RESOLUTION. IF YOU WISH TO VOTE AGAINST THE RESOLUTION, PLEASE TICK THE BOX MARKED "AGAINST" BESIDE THE RESOLUTION. IF YOU WISH TO ABSTAIN FROM VOTING ON THE RESOLUTION, PLEASE TICK THE BOX MARKED "ABSTAIN" BESIDE THE RESOLUTION. IN COUNTING THE VOTING RESULTS FOR A RESOLUTION, ABSTAINED VOTES WILL BE REGARDED AS VOTES WITH VOTING RIGHTS. If no direction is given, your proxy may vote or abstain at his/her discretion. Your proxy will also be entitled to vote at his/her discretion on any resolution properly put to the Meeting other than those referred to in the notice convening the Meeting.
6. This form of proxy must be signed by you or your attorney duly authorised in writing. In the case of a corporation, this form of proxy must be either under its common seal or under the hand of its director(s) or duly authorised attorney(s). If this form of proxy is signed by an attorney of the shareholder, the power of attorney authorising that attorney to sign or other authorisation document must be notarized.
7. To be valid, this form of proxy together with any power of attorney or other authorisation document (if any) under which it is signed or a notarized copy of that power of attorney or authorisation document must be lodged with the Company's H share registrar in Hong Kong, Computershare Hong Kong Investor Services Limited, at Shops 17M Floor, Hopewell Centre, 183 Queen's Road East, Wan Chai, Hong Kong (for holders of H shares), no later than 24 hours before the time appointed for holding the Meeting or any adjournment thereof. Completion and return of the form of proxy will not preclude you from attending and voting in person at the Meeting if you so wish. In such event, your form of proxy will be deemed to have been revoked.
8. Shareholders or their proxies attending the Meeting shall present their identity documents.
9. A proxy need not be a shareholder of the Company but must attend the Meeting in person to represent the shareholder.
10. In the case of joint registered holders of any shares, any one of such joint registered holders may vote at the Meeting, either in person or by proxy, in respect of such shares as if he/she/it were solely entitled thereto; but should more than one of such joint registered holders be present at the Meeting, either in person or by proxy, the vote of that one of them so present, whose name stands first on the register of members of the Company in respect of such shares shall be accepted to the exclusion of the votes of the other joint registered holder(s).