TG THERAPEUTICS, INC. — Director's Dealing 2004

Feb 4, 2004

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: MANHATTAN PHARMACEUTICALS INC (MHTT)
CIK: 0001001316
Period of Report: 2004-01-28

Reporting Person: ROSSETTOS NICHOLAS J (Chief Financial Officer)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2004-01-28	Stock Option	$1.65	A	150000	Acquired	2014-01-28	Common Stock (150000)	Direct

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Stock Options	$20.94	2010-04-12	Common Stock (10000)	10000	Direct
Stock Options	$4.375	2011-02-20	Common Stock (10000)	10000	Direct
Stock Options	$1.25	2012-02-19	Common Stock (10000)	10000	Direct
Stock Options	$1.25	2012-02-19	Common Stock (10000)	10000	Direct
Stock Options	$1	2012-03-28	Common Stock (25000)	25000	Direct
Stock Options	$.4	2013-02-24	Common Stock (292030)	292030	Direct
Stock Options	$1.25	2012-02-19	Common Stock (10000)	10000	Direct

Footnotes

F1: (Right to buy)

F2: Currently exercisable.

F3: 2,500 shares each vest on 2/20/01, 2/20/02, 2/20/03 and 2/20/04.

F4: 2,500 shares each vest on 2/19/02, 2/19/03, 2/19/04 and 2/19/05.

F5: 146,015 shares are currently vested; 146,015 shares vest on 2/24/05.

F6: Option vests on the earlier of FDA approval or Catarex or 2/19/07.

F7: 50,000 shares each vest on 1/28/04, 1/28/05 and 1/28/06.