Tempus AI, Inc. — Director's Dealing 2025

Aug 21, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Tempus AI, Inc. (TEM)
CIK: 0001717115
Period of Report: 2025-08-19

Reporting Person: LEFKOFSKY ERIC P (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-08-19	Class A Common Stock	S	17033	$74.63	Disposed	2020467	Direct
2025-08-19	Class A Common Stock	S	425	$75.61	Disposed	2020042	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Class A Common Stock	9274033	Indirect
Class A Common Stock	18135469	Indirect
Class A Common Stock	406	Indirect
Class A Common Stock	10000000	Indirect
Class A Common Stock	206	Indirect
Class A Common Stock	332131	Indirect

Footnotes

F1: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $74.36 to $75.2673 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3: The Reporting Person is (i) a member of, and controls a limited liability company that is a member of, 346 Long LLC, (ii) the sole manager of each of Black Media, LLC, Blue Media, LLC and Gray Media, LLC and (iii) a trustee of Lefkofsky Family Foundation. The Reporting Person's spouse is the trustee of the Lefkofsky Family 2025 GRAT.