Tectonic Therapeutic, Inc. — Director's Dealing 2025

Sep 29, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Tectonic Therapeutic, Inc. (TECX)
CIK: 0001681087
Period of Report: 2025-09-25

Reporting Person: REICIN ALISE (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-09-25	Common Stock	A	14700	—	Acquired	228185	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-09-25	Employee Stock Option (Right to Buy)	$14.71	A	26710	Acquired	2035-09-24	Common Stock (26710)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	124530	Indirect

Footnotes

F1: These shares are represented by restricted stock units. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. The shares shall vest in 3 equal annual installments on each of September 25, 2026, September 25, 2027 and September 25, 2028, subject to the Reporting Person's continued service to the Issuer on each such vesting date.

F2: These shares are held by the Reicin-Boiarsky Family Trust (the "Trust"). The Reporting Person's spouse is a co-trustee of the Trust. Accordingly, the Reporting Person may be deemed to have shared voting and dispositive power over the securities held by the Trust. The Reporting Person disclaims beneficial ownership of the shares held by the Trust except to the extent of her pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.

F3: The shares subject to the option vest in 48 equal monthly installments beginning on October 25, 2025, subject to the Reporting Person's continued service to the Issuer on each such vesting date.