Tel Aviv Stock Exchange Ltd. — Major Shareholding Notification 2023

Nov 6, 2023

Novo Holdings A/S becomes an Interested Party false

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THE TEL-AVIV STOCK EXCHANGE LTD
Corporation no: 520020033	14778
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	Israel Securities Authority			Tel Aviv Stock Exchange		�150 ( Public )		Reported via MAGNA:	06/11/2023
	www.isa.gov.il			www.tase.co.il				Reference:	2023-01-122118	Time of broadcast: 21:58 21:58

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English language report to Israeli corporateThis form is for reports that has been translated to English (convenience translation) and should be published alongside with the report in Hebrew in accordance with the Securities Regulations (Periodic and Immediate Reports), 5730 - 1970.

References of previous reports relating to this matter:   _________   _________   _________

The Company is pleased to announce the receipt, on 2.11.2023, of a notification from Novo Holdings A/S (hereafter: �the Interested Party�), a foreign company registered in Denmark, informing the Company that it is now an interested party in the Company, following the purchase in an OTC transaction of 4,312,024 shares for a consideration of NIS 17.3 per share. Subsequent to the aforesaid purchase, the Interested Party holds 7,785,515 shares of the Company, representing approximately 8.42% of the Company�s issued share capital and the voting rights therein. Additionally, the Interested Party has informed the Company that it holds a holding permit from the Israel Securities Authority for a holding of up to 10%, subject to the terms set out in said permit. To complete the picture, it should be noted that the Interested Party is a subsidiary of Novo Nordisk Foundation, a business fund without a controlling shareholder, incorporated in Denmark.

Attached hereto is a report on	Novo Holdings A/S becomes an Interested Party

_________

	Reference to parallel Hebrew report:	2023-01-100627
	This report was not reported in Hebrew.

Details of the authorized signatories to sign on behalf of the corporation:

	Name of the signer	Corporate Role
1	Ittai Ben Zeev	CEO _________

Note: According to Rule 5 of the Periodic and Immediate Reports Regulations (1970), a report submitted under these Regulations will be signed by the authorized persons to sign on behalf of the corporation. For the ISA staff notice Click here .2 2

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
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Stock Exchange/Market: ������ ���� ���	Date of revision of form structure: 10/10/2023
Address: ����� ��� 2, �"� 29060 ����� 6129001 , �� ���� 6525216   , Tel: 076-8160571 , Fax: 076-8160331
E-mail address: gilc@tase.co.il   Company site: tase.co.il
Previous names of reporting entity:
Name of the Signatory: ��� ���� ���� Position of Signatory in the reporting corporation: Name of Employer Company:
Address: ����� ��� 2 , �� ���� 6525216 Telephone: 076-8160571 Facsimile: 076-8160331 E-mail: efratb@tase.co.il 1