SYNTARA LIMITED — Director's Dealing 2009

Jul 5, 2009

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6 July 2009

Manager ASX Companies Announcement Office

Dear Sir,

Appendix 3Y

Attached is an amended Appended 3Y. The document filed earlier today incorrectly stated the date of change as 1 July 2007 rather than 30 June 2009.

We apologise for the oversight.

Sincerely,

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David McGarvey Company Secretary

Pharmaxis Ltd 20 Rodborough Road T 02 9454 7200 ABN 75 082 811 630 Frenchs Forest NSW 2086 F 02 9451 3622 Australia www.pharmaxis.com.au

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity PHARMAXIS LTD ABN 75 082 811 630

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Denis Michael Hanley
Date of last notice	21 November 2007

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Change in direct and two indirect interests
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to therelevant interest.	Shares acquired by Denis Hanley Pty Ltd as trustee forthe Denis M Hanley Family Trust of which DenisHanley is a potential beneficiaryShares acquired by Denis Hanley as trustee of the DenisHanley Superannuation Fund of which Denis Hanley is apotentialbeneficiary
Date of change	30 June 2009
No. of securities held prior to change	Ordinary shares held directly: 567,946Ordinary shares held indirectly: 203,895Options overordinary shares:1,120,000
Class	Ordinary shares
Number acquired	2,127 ordinary shares acquired directly2,127 ordinary shares acquired on behalf of the Denis MHanley Family Trust2,127 ordinary shares acquired on behalf of the DenisHanley Superannuation Fund
Number disposed	Nil
Value/ConsiderationNote: If consideration is non-cash, provide details andestimated valuation	A$2.35 per share

• See chapter 19 for defined terms.

Appendix 3Y Page 1

11/3/2002

Appendix 3Y Change of Director’s Interest Notice

No. of securities held after change	Ordinary shares held directly: 570,073Ordinary shares held indirectly: 208,149Options over ordinary shares: 1,120,000
Nature of changeExample: on-market trade, off-market trade, exercise ofoptions, issue of securities under dividend reinvestment plan,participation in buy-back	Purchase under share purchase plan

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	N/A
Nature of interest
Name of registered holder(if issued securities)
Date of change
No. and class of securities towhich interest related prior tochangeNote: Details are only required for a contract in relationto which the interest has changed
Interest acquired
Interest disposed
Value/ConsiderationNote: If consideration is non-cash, provide details andan estimated valuation
Interest after change

• See chapter 19 for defined terms.

Appendix 3Y Page 2

11/3/2002