SYNLOGIC, INC. — Director's Dealing 2015

Oct 6, 2015

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Mirna Therapeutics, Inc. (MIRN)
CIK: 0001527599
Period of Report: 2015-10-05

Reporting Person: POWELL MICHAEL (Director, 10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2015-10-05	Common Stock	C	1244269	—	Acquired	1244269	Indirect
2015-10-05	Common Stock	C	583559	—	Acquired	1827828	Indirect
2015-10-06	Common Stock	J	289841	$0.00	Acquired	2117669	Indirect
2015-10-06	Common Stock	P	857142	$7.00	Acquired	2974811	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2015-10-05	Series C Preferred Stock	$	C	1244269	Disposed		Common Stock (1244269)	Indirect
2015-10-05	Series D Preferred Stock	$0.00	C	583559	Disposed		Common Stock (583559)	Indirect

Footnotes

F1: Each share of Series C and Series D Preferred Stock automatically converted on a one-to-one basis into Common Stock upon the consummation of the Issuer's initial public offering.

F2: The shares are held by Sofinnova Venture Partners VIII, L.P. ("SVP VIII"). Sofinnova Management VIII, L.L.C. ("SM VIII") is the general partner of SVP VIII. The individual Managers, or the Managing Members, of SM VIII are Michael Powell, James Healy, Srinivas Akkaraju and Anand Mehra. The Managers share voting and dispositive power with regard to the shares held directly by SVP VIII. Such persons and entities disclaim beneficial ownership over the shares owned by SVP VIII except to the extent of any pecuniary interest therein.

F3: The shares were issued for no additional consideration pursuant to an accruing paid-in-kind dividend on shares of Series C and Series D Preferred Stock of the Company.

F4: The expiration date is not relevant to the conversion of these securities.

F5: Due to a clerical error, the Reporting Person's Form 3 which previously reported the holding of these shares understated his total by one (1) share.