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Structure Therapeutics Inc. Director's Dealing 2026

Jan 20, 2026

31940_dirs_2026-01-20_6d06d97f-a5c4-4b87-b272-2c8e49a277c8.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Structure Therapeutics Inc. (GPCR)
CIK: 0001888886
Period of Report: 2026-01-15

Reporting Person: FMR LLC (N/A)

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2026-01-15 American Depositary Shares $ S 465 Disposed Ordinary Shares (1395) Indirect
2026-01-15 American Depositary Shares $ S 330 Disposed Ordinary Shares (990) Indirect
2026-01-15 American Depositary Shares $ S 552 Disposed Ordinary Shares (1656) Indirect
2026-01-15 American Depositary Shares $ S 20 Disposed Ordinary Shares (60) Indirect
2026-01-15 American Depositary Shares $ S 5477 Disposed Ordinary Shares (16431) Indirect
2026-01-15 American Depositary Shares $ S 3880 Disposed Ordinary Shares (11640) Indirect
2026-01-15 American Depositary Shares $ S 6498 Disposed Ordinary Shares (19494) Indirect
2026-01-15 American Depositary Shares $ S 230 Disposed Ordinary Shares (690) Indirect

Holdings (Non-Derivative)

Security Shares Ownership
Ordinary Shares 20502 Indirect
Ordinary Shares 241275 Indirect

Holdings (Derivative)

Security Exercise Price Expiration Underlying Shares Ownership
American Depositary Shares $ Ordinary Shares (4546674) 1515558 Indirect

Footnotes

F1: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer.

F2: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $82.00 to $82.37. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F3: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $83.00 to $83.84. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F4: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $84.00 to $84.64. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information

F5: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $85.02 to $85.06. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information