SPRUCE BIOSCIENCES, INC. — Director's Dealing 2023

May 26, 2023

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: SPRUCE BIOSCIENCES, INC. (SPRB)
CIK: 0001683553
Period of Report: 2023-05-25

Reporting Person: Ways Kirk (Director)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2023-05-25	Stock Option (Right to Buy)	$2.26	A	30000	Acquired	2033-05-24	Common Stock (30000)	Direct

Footnotes

F1: The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2024 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the "Plan")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan).