SOPHiA GENETICS — Proxy Solicitation & Information Statement 2026

May 8, 2026

6-K 1 agm2026sophiageneticssa6-k.htm 6-K Document created using Wdesk Copyright 2026 Workiva Document

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of May 2026.

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Commission File Number: 001-40627

SOPHiA GENETICS SA

(Exact name of registrant as specified in its charter)

La Pièce 12

CH-1180 Rolle

Switzerland

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Form 20-F x Form 40-F

SIGNATURE

SOPHiA GENETICS SA (the “Company”) provided to its shareholders an invitation to the Company’s annual general meeting of shareholders. The annual general meeting of shareholders is expected to take place on June 18, 2026 at 8:00 a.m. EDT / 2:00 p.m. CEST at the Company’s office at La Pièce 12, 1180 Rolle/VD, Switzerland.

May 8, 2025
By:	/s/ Daan van Well
Name:	Daan van Well
Title:	Chief Legal and Regulatory Officer

EXHIBIT INDEX

Exhibit No.	Description
99.1	Invitation to the Annual General Meeting 2026
99.2	Shareholder Annual General Meeting Notice 2026
99.3	Annual General Meeting Proxy Card (Broker) 2026
99.4	Annual General Meeting Proxy Card (Common Shareholder) 2026