SOLIGENIX, INC. — Director's Dealing 2009

Sep 28, 2009

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: DOR BIOPHARMA INC (DORB)
CIK: 0000812796
Period of Report: 2009-09-24

Reporting Person: SIGMA TAU FINANZIARIA SPA (10% Owner)
Reporting Person: SIGMA TAU INTERNATIONAL SA (10% Owner)
Reporting Person: Sigma-Tau America S.A. (10% Owner)
Reporting Person: Sigma-Tau Pharmaceuticals, Inc. (10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2009-09-24	Common Stock	P	3952569	$0.253	Acquired	45619236	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2009-09-24	Common Stock Warrant (right to buy)	$0.278	J	1	Acquired	2014-09-27	Common Stock (1976284)	Indirect

Footnotes

F1: Shares directly owned by Sigma-Tau Pharmaceuticals, Inc. (?Pharmaceuticals?). Pharmaceuticals is a direct wholly-owned subsidiary of Sigma-Tau America S.A. (?America?). America is a direct wholly-owned subsidiary of Sigma-Tau International S.A. (?International?). International is a direct wholly-owned subsidiary of Sigma-Tau Finanziaria S.p.A.

F2: This warrant was issued by the Issuer to Pharmaceuticals in consideration of Pharmaceuticals? purchase of 3,952,569 shares of common stock on September 24, 2009.

F3: The expiration date of the warrant may be accelerated at the Issuer?s option if the Issuers?s common stock meets certain price thresholds and the common shares underlying the warrant are registered for resale pursuant to an effective registration statement or are freely transferable without volume restrictions pursuant to Rule 144 under the Securities Act of 1933, as amended.