Solid Biosciences Inc. — Major Shareholding Notification 2025

Apr 18, 2025

xml version="1.0" encoding="UTF-8"? SCHEDULE 13G/A 0002005369 XXXXXXXX LIVE 4 Common Stock, $0.001 par value per share 03/31/2025 0001707502 Solid Biosciences Inc. 83422E204 500 RUTHERFORD AVENUE 3RD FLOOR CHARLESTOWN MA 02129 Rule 13d-1(c) Invus Public Equities, L.P. D0 6402653 0 6402653 0 6402653 N 8.3 PN Invus Public Equities Advisors, LLC DE 6402653 0 6402653 0 6402653 N 8.3 OO Invus Global Management, LLC DE 6402653 0 6402653 0 6402653 N 8.3 OO Siren, L.L.C. DE 6402653 0 6402653 0 6402653 N 8.3 OO Avicenna Life Sci Master Fund LP E9 1013252 0 1013252 0 1013252 N 1.3 PN Avicenna Life Sci Master GP LLC DE 1013252 0 1013252 0 1013252 N 1.3 OO Ulys, L.L.C. DE 1013252 0 1013252 0 1013252 N 1.3 OO Raymond Debbane R1 7415905 0 7415905 0 7415905 N 9.6 IN Solid Biosciences Inc. 500 Rutherford Avenue, Third Floor, Charlestown, MA 02129 See Item 2(c) below. See Item 2(c) below. (i) Invus Public Equities, L.P. ("Invus Public Equities") 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Bermuda limited partnership (ii) Invus Public Equities Advisors, LLC ("Invus PE Advisors") 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Delaware limited liability company (iii) Invus Global Management, LLC ("Global Management") 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Delaware limited liability company (iv) Siren, L.L.C. ("Siren") c/o The Invus Group, LLC, 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Delaware limited liability company (v) Avicenna Life Sci Master Fund LP ("Avicenna Fund") 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Cayman Islands limited partnership (vi) Avicenna Life Sci Master GP LLC ("Avicenna GP") 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Delaware limited liability company (vii) Ulys, L.L.C. ("Ulys") 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Delaware limited liability company (viii) Mr. Raymond Debbane 750 Lexington Avenue, 30th Floor, New York, NY 10022 Citizenship: Panama The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons." Y As of March 31, 2025, Invus Public Equities directly held 6,402,653 shares of Common Stock, $0.001 par value per share (the "Shares") and Avicenna Fund directly held 1,013,252 Shares. Invus PE Advisors, as the general partner of Invus Public Equities, controls Invus Public Equities and, accordingly, may be deemed to beneficially own the Shares directly held by Invus Public Equities. Global Management, as the managing member of Invus PE Advisors, controls Invus PE Advisors and, accordingly, may be deemed to beneficially own the Shares that Invus PE Advisors may be deemed to beneficially own. Siren, as the managing member of Global Management, controls Global Management and, accordingly, may be deemed to beneficially own the Shares that Global Management may be deemed to beneficially own. Avicenna GP, as the general partner of Avicenna Fund, controls Avicenna Fund and, accordingly, may be deemed to beneficially own the Shares beneficially held by Avicenna Fund. Ulys, as the managing member of Avicenna GP, controls Avicenna GP and, accordingly, may be deemed to beneficially own the Shares that Avicenna GP may be deemed to beneficially own. Mr. Raymond Debbane, as the managing member of Siren and Ulys, controls Siren and Ulys and, accordingly, may be deemed to beneficially own the Shares that Siren and Ulys may be deemed to beneficially own. As of March 31, 2025, each of the Reporting Persons may be deemed to be the beneficial owner of the Shares listed on such Reporting Person's cover page. Calculations of the percentage of Shares beneficially owned are based on 77,492,959 Shares outstanding as of March 3, 2025 as reported in the Annual Report on Form 10-K filed by Solid Biosciences Inc. with the Securities and Exchange Commission on March 6, 2025. See each cover page hereof. See each cover page hereof. See each cover page hereof. See each cover page hereof. See each cover page hereof. Y Y Y Y Y N Each of the Reporting Persons hereby makes the following certification: By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Invus Public Equities, L.P. /s/ Raymond Debbane Raymond Debbane, President, Invus Public Equities Advisors, LLC, its general partner 04/17/2025 Invus Public Equities Advisors, LLC /s/ Raymond Debbane Raymond Debbane, President 04/17/2025 Invus Global Management, LLC /s/ Raymond Debbane Raymond Debbane, President 04/17/2025 Siren, L.L.C. /s/ Raymond Debbane Raymond Debbane, President 04/17/2025 Avicenna Life Sci Master Fund LP /s/ Raymond Debbane Raymond Debbane, Chief Executive Officer, Avicenna Life Sci Master GP LLC, its general partner 04/17/2025 Avicenna Life Sci Master GP LLC /s/ Raymond Debbane Raymond Debbane, Chief Executive Officer 04/17/2025 Ulys, L.L.C. /s/ Raymond Debbane Raymond Debbane, President 04/17/2025 Raymond Debbane /s/ Raymond Debbane Raymond Debbane, 04/17/2025