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Silence Therapeutics plc Director's Dealing 2021

Jan 6, 2021

33536_mda_2021-01-06_c57a1331-a4be-48f3-b714-7ba955a1284d.html

Director's Dealing

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National Storage Mechanism | Additional information

RNS Number : 7819K

Silence Therapeutics PLC

06 January 2021

Grant of Options

January 6, 2021

LONDON, Silence Therapeutics plc, AIM:SLN and NASDAQ: SLN ("Silence" or "the Company") a leader in the discovery, development and delivery of novel short interfering ribonucleic acid (siRNA) therapeutics for the treatment of diseases with significant unmet medical need, today announced that it has granted 580,000 options to Craig Tooman, Chief Financial Officer, under the Silence Therapeutics plc 2018 Employee Long Term Incentive Plan.

Under the grant, 145,000 options will vest on the 12-month anniversary of the award.  A further 36,250 share options will vest at the end of each subsequent quarter following the 12- month anniversary for the following 12 quarters.  The options will have a strike price of £5.26, the mid-market closing price on AIM on January 5, 2021.

Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them

1. Details of the person discharging managerial responsibilities (PDMR) / person closely associated
a) Name Craig Tooman
2. Reason for the notification
a) Position / status Chief Financial Officer
b) Initial notification / Amendment Initial notification
3. Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a) Name Silence Therapeutics plc
b) LEI 213800SSURRJBX85SQ91
4 Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a) Description of the financial instrument, type of instrument

Identification code
Ordinary Shares in Silence Therapeutics plc

ISIN for Silence Therapeutics plc Ordinary Shares:

GB00B9GTXM62
b) Nature of the transaction Grant of Options under the Silence Therapeutics plc 2018 Employee LTIP Scheme
c) Prices(a) and volume(s) 580,000 options with strike price of £5.26
d) Aggregated information

- Aggregated volume

- Price
580,000

£5.26
e) Date of the transaction 6 January 2021
f) Place of the transaction Outside a trading venue

Enquiries:

Silence Therapeutics plc

Gem Hopkins, Head of IR and Corporate Communications

[email protected]
Tel:  +1 (646) 637-3208
Investec Bank plc (Nominated Adviser and Broker)

Daniel Adams/Gary Clarence
Tel:  +44 (0) 20 7597 5970
European IR

Consilium Strategic Communications

Mary-Jane Elliott/ Angela Gray / Chris Welsh

[email protected]
Tel: +44 (0) 20 3709 5700
U.S. IR

Westwicke Partners

Peter Vozzo

[email protected]
Tel: +1 (443) 213-0505

About Silence Therapeutics

Silence Therapeutics is developing a new generation of medicines by harnessing the body's natural mechanism of RNA interference, or RNAi, to inhibit the expression of specific target genes thought to play a role in the pathology of diseases with significant unmet medical need. Silence's proprietary technology can be used to engineer short interfering ribonucleic acids (siRNAs) that bind specifically to and silence, through the RNAi pathway, almost any gene in the human genome to which siRNA can be delivered. Silence's wholly owned product candidates include SLN360 designed to address the high and prevalent unmet medical need in reducing cardiovascular risk in people born with high levels of Lipoprotein(a) and SLN124 to address beta-thalassemia and myelodysplastic syndrome. Silence is also developing SLN500, a C3 targeting program, in partnership with Mallinckrodt Pharmaceuticals to reduce the expression of the C3 protein for the treatment of complement pathway-mediated diseases.  Silence maintains ongoing research and collaborations with AstraZeneca, Mallinckrodt Pharmaceuticals and Takeda. For more information, please visit: https://www.silence-therapeutics.com/

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