Silence Therapeutics plc — Director's Dealing 2020

Dec 3, 2020

National Storage Mechanism | Additional information

RNS Number : 4344H

Silence Therapeutics PLC

03 December 2020

Director Dealing

3rd December 2020

LONDON, Silence Therapeutics plc, AIM:SLN and Nasdaq: SLN ("Silence" or "the Company"), a leader in the discovery, development and delivery of novel short interfering ribonucleic acid (siRNA) therapeutics for the treatment of diseases with significant unmet medical need, today announces that, on the 30th November 2020 and 1st December 2020, 4,700 and 1,000 American Depositary Shares ("ADSs") respectively were purchased by Mark Rothera, Chief Executive Officer of the Company, at $18.20 per ADS. Each ADS is a tradeable security representing 3 of the Company's Ordinary Shares 

Following this purchase, Mark Rothera is interested in 5,700 ADSs representing 17,100 ordinary shares (0.02%) of the issued share capital of the Company.

Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them

1.

Details of the person discharging managerial responsibilities (PDMR) / person closely associated

a)

Name

Mark Rothera

2.

Reason for the notification

a)

Position / status

Chief Executive Officer

b)

Initial notification / Amendment

Initial notification

3.

Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor

a)

Name

Silence Therapeutics plc

b)

LEI

213800SSURRJBX85SQ91

4

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted

a)

Description of the financial instrument, type of instrument

Identification code

American Depositary Shares (ADS), each of which represents three (3) Ordinary Shares of 5 pence each in the capital of Silence Therapeutics plc

ISIN US82686Q1013

b)

Nature of the transaction

Purchase of Silence Therapeutics plc ADS

c)

Prices(a) and volume(s)

Price(s)	Volume(s)
$17.98	1200 ADSs
$17.99	500 ADSs
$18.99	800 ADSs
$18.35	200 ADSs
$18.00	2000 ADSs
$18.30	1000 ADSs

d)

Aggregated information

- Aggregated volume

- Price

Aggregate Volume: 5,700 ADSs

Metric for Quantity: ADSs

Aggregated Volume Price per ADS: $18.20

e)

Date of the transaction

30 November 2020 (Time zone: Eastern Standard Time)

1 December 2020 (Time zone: Eastern Standard Time)

f)

Place of the transaction

Nasdaq Capital Market

Enquiries:

Silence Therapeutics plc  Gem Hopkins, Head of IR & Corporate Communications	Tel:  +1 (646) 637-3208
Investec Bank plc (Nominated Adviser and Broker) Daniel Adams/Gary Clarence	Tel:  +44 (0) 20 7597 5970
European IR Consilium Strategic Communications Mary-Jane Elliott/Chris Welsh/Angela Gray [email protected]	Tel: +44 (0) 20 3709 5700
US IR Westwicke Partners Peter Vozzo [email protected]	Tel: +1 (443) 213-0505

About Silence Therapeutics plc

Silence Therapeutics is developing a new generation of medicines by harnessing the body's natural mechanism of RNA interference, or RNAi, to inhibit the expression of specific target genes thought to play a role in the pathology of diseases with significant unmet medical need. Silence's proprietary technology can be used to engineer short interfering ribonucleic acids (siRNAs) that bind specifically to and silence, through the RNAi pathway, almost any gene in the human genome to which siRNA can be delivered. Silence's wholly owned product candidates include SLN360 designed to address the high and prevalent unmet medical need in reducing cardiovascular risk in people born with high levels of Lipoprotein(a) and SLN124 to address beta-thalassemia and myelodysplastic syndrome. Silence is also developing a C3 targeting programme, SLN500, in partnership with Mallinckrodt Pharmaceuticals to reduce the expression of the C3 protein for the treatment of complement pathway-mediated diseases.  Silence maintains ongoing research and collaborations with AstraZeneca, Mallinckrodt Pharmaceuticals and Takeda. For more information, please visit: https://www.silence-therapeutics.com/

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