SERA PROGNOSTICS, INC. — Director's Dealing 2025

Dec 3, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: SERA PROGNOSTICS, INC. (SERA)
CIK: 0001534969
Period of Report: 2025-12-02

Reporting Person: Kearney Paul (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-02	Class A Common Stock	M	32203	$1.62	Acquired	200799	Direct
2025-12-02	Class A Common Stock	S	32203	$2.94	Disposed	168596	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-12-02	Stock Option (right to buy)	$1.62	M	32203	Disposed	2025-12-11	Class A Common Stock (34189)	Direct

Footnotes

F1: This Form 4 reports the exercise of an employee stock option by the Reporting Persion that was granted approximately 10 years ago and that would otherwise expire on December 11, 2025 if not exercised during the issuer's open trading window for insiders.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.79 to $3.14, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price.

F3: The shares subject to this option are fully vested and exercisable.