Sequana Medical N.V.

Major Shareholding Notification • Nov 24, 2025

Transparency notification Form TR-1 BE PART I

1) Status of the notification

Final

2) Issuer

Name
SEQUANA MEDICAL

Identification number
0707-821-866

3) Reason for the notification

Acquisition or disposal of voting securities or voting rights

Downward crossing of the lowest threshold

-+

4) Notification by

A parent undertaking or a controlling person

5) Persons subject to the notification requirement

Name	Address (for legal entities)
BlackRock, Inc.	50 Hudson Yards, New York, NY, 10001, U.S.A.
BlackRock Saturn Subco, LLC	Corporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, U.S.A.
BlackRock Finance, Inc.	Corporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, U.S.A.
BlackRock Holdco 2, Inc.	Corporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, U.S.A.
BlackRock Financial Management, Inc.	50 Hudson Yards, New York, NY, 10001, U.S.A.
BlackRock International Holdings, Inc.	Corporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, U.S.A.
BR Jersey International Holdings L.P.	Thomas Edge House, Tunnell Street, St Helier, Jersey JE2 4LU
BlackRock Holdco 3, LLC	Corporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, U.S.A.
BlackRock Cayman 1 LP	Walkers Corporate Limited, 190 Elgin Avenue, George Town, Grand Cayman KY1-9008
BlackRock Cayman West Bay Finco Limited	Walkers Corporate Limited, 190 Elgin Avenue, George Town, Grand Cayman KY1- 9008
BlackRock Cayman West Bay IV Limited	Walkers Corporate Limited, 190 Elgin Avenue, George Town, Grand Cayman KY1-9008
BlackRock Group Limited	12 Throgmorton Avenue, London, EC2N 2DL, U.K.
BlackRock Crane Limited	12 Throgmorton Avenue, London, EC2N 2DL, U.K.
Kreos Capital Management Limited	47 Esplanade, St Helier, Jersey JE1 0BD
Kreos Capital Group VII Limited	47 Esplanade, St Helier, Jersey JE1 0BD
Kreos Capital Group VII LP	47 Esplanade, St Helier, Jersey JE1 0BD
Kreos Capital VII Aggregator ScSp	33, Avenue JF Kennedy, L-1855 Luxembourg

6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)

Name	Address (for legal entities)

Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6

Part II

7) Date on which the threshold is crossed

13/11/2025 (DD/MM/YYYY)

8) Threshold that is crossed (in %)

9) Denominator

65,759,928

Please enter the denominator before filling in the data

10) Notified details

A) Voting rights	After the transaction Previous notification
	# of voting rights	# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
BlackRock Inc	0	0		0.00%
Kreos Capital VII Aggregator ScSp	2,379,849	1,950,507		2.97%
Subtotal	2,379,849	1,950,507		2.97%
	TOTAL	1,950,507		2.97%

Start with "groups" of holders. Add subtotals with Σ, and then finish with the persons who are "alone".

For groups, start with the ultimate controlling natural person or legal entity. The totals, subtotals and % will be updated once you have clicked on .

B) Equivalent financial instruments	Affect the transporting
b) Equivalent infancial instruments	After the transaction						-
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
	TOTAL
The totals will be updated once you have clicked on
	TOTAL (A & B)			# of voting rights	% of voting rights
			CALCULATE	1,950,507	2.97%
11) Full chain of controlled undertakings through which the holding is effectively held, if applicable
	Please see the full chain of control in "Chain of Contro	" tab.
12) In case of proxy voting for	or only one GM
Holder		will cease to hold / will hold again	0		voting rights as of	(DD/MM/YYYY)
13) Additional information
The disclosure obligation arose due to to	otal holdings in voting rights for BlackRock, Inc. going b	elow 3%. Additionally	, voting rights attached	d to shares for Black	Rock, Inc. went below	3%.
Done at	12 Throgmorton Avenue, London EC2N 2DL, U.K.
On	14/11/2025	(DD/MM/YYYY)
Name & capacity	Jana Blumenstein, Director		Signature	J. Bleece	eeeste.

For security reasons, the unsigned form in xlsx format should be transmitted to trp.fin@fsma.be. You can do this manually OR if you have MS Outlook at your disposal via the "Save & Send" button.

In addition, a signed copy in $\underline{\mathsf{PDF}}$ format should also be transmitted.

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

Name

BlackRock, Inc.

BlackRock Saturn Subco, LLC

BlackRock Finance, Inc.

BlackRock Holdco 2, Inc.

BlackRock Financial Management, Inc.

BlackRock International Holdings, Inc.

BR Jersey International Holdings L.P.

BlackRock Holdco 3, LLC

BlackRock Cayman 1 LP

BlackRock Cayman West Bay Finco Limited

BlackRock Cayman West Bay IV Limited

BlackRock Group Limited

BlackRock Crane Limited

Kreos Capital Management Limited

Kreos Capital Group VII Limited

Kreos Capital Group VII LP

Kreos Capital VII Aggregator ScSp