Schrodinger, Inc. — Director's Dealing 2026

Mar 3, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Schrodinger, Inc. (SDGR)
CIK: 0001490978
Period of Report: 2026-03-02

Reporting Person: Tran Yvonne (EVP, CLO & CPO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2026-03-02	Common Stock	A	17130	—	Acquired	39989	Direct
2026-03-02	Common Stock	A	13788	—	Acquired	53777	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-03-02	Stock Option (right to buy)	$12.15	A	34250	Acquired	2036-03-02	Common Stock (34250)	Direct

Footnotes

F1: Grant of restricted stock units ("RSUs") under the Issuer's 2022 Equity Incentive Plan, as amended. Each RSU represents a contingent right to receive one share of common stock of the Issuer. The RSUs were granted on March 2, 2026 and will vest in equal installments on each of March 9, 2027, 2028, 2029 and 2030, subject to the reporting person's continued service with the company.

F2: Represents portion of the performance-based restricted stock units ("PRSUs") previously granted to the reporting person on March 4, 2024, for which the compensation committee of the Issuer's board of directors certified on March 2, 2026 the level of achievement of the performance metrics for the PRSUs. The PRSUs will vest upon the filing of the Issuer's Annual Report on Form 10-K for the year ended December 31, 2026, subject to the reporting person's continued service with the company.

F3: Includes an aggregate of 45,316 unvested RSUs.

F4: The option was granted on March 2, 2026. The shares underlying the option are scheduled to vest with respect to 25% of the shares on March 2, 2027 and the remainder are scheduled to vest in equal monthly installments through March 2, 2030, subject to the reporting person's continued service with the company.