Sarepta Therapeutics, Inc. — Director's Dealing 2010

Feb 11, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: AVI BIOPHARMA INC (AVII)
CIK: 0000873303
Period of Report: 2010-02-09

Reporting Person: kole Ryszard (SVP/Discovery Research)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2010-02-09	Incentive Stock Option (right to buy)	$1.45	A	47184	Acquired	2020-02-09	Common Stock (47184)	Direct
2010-02-09	Non-Qualified Stock Option (right to buy)	$1.45	A	72816	Acquired	2020-02-09	Common Stock (72816)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	1862926	Direct

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Incentive Stock Option (right to buy)	$0.92	2019-02-10	Common Stock (100000)	100000	Direct
Incentive Stock Option (right to buy)	$1.71	2018-04-10	Common Stock (150000)	150000	Direct

Footnotes

F1: The Stock Option Grant vest as follows: 1/3 vest one year from date of grant and 1/3 each year thereafter until all shares vest three years from grant date.

F2: Price not required on initial report of stock option granted.

F3: Option Grant vests 25% per year on grant date with all shares vesting four years from date of grant.