RYVU Therapeutics S.A. — Director's Dealing 2024

May 22, 2024

Report Content Notification from person discharging managerial responsibilities in theCompany due to execution of the Stock Grant Program - Article 19 of MAR

The Management Board of Ryvu Therapeutics S.A. with its registeredoffice in Krakow, Poland (_quot;Company_quot;) hereby informs that the Companyreceived a notification prepared in accordance with Article 19.1 of MARfrom Mr. Paweł Przewięźlikowski - President of the Management Board asfrom the person discharging managerial responsibilities in the Companydue to the implementation of the Stock Grant Program about which theCompany informed in the current reports No. 10/2021 of April 20th, 2021and No. 14/2021 of May 17th, 2021. The notification is attached to thisreport.

Disclaimer: This English language translation has been prepared solelyfor the convenience of English-speaking readers. Despite all the effortsdevoted to this translation, certain discrepancies, omissions orapproximations may exist. In case of any differences between the Polishand the English versions, the Polish version shall prevail. RyvuTherapeutics S.A., its representatives and employees decline allresponsibility in this regard.