RYVU Therapeutics S.A. — Director's Dealing 2023

Jul 21, 2023

Notification from a person discharging managerial responsibilities inthe Company - Article 19 of MAR

The Management Board of Ryvu Therapeutics S.A. (_quot;Company_quot;) herebyinforms that the Company received a notification prepared on the basisof Article 19(1) of the Market Abuse Regulation from Mr Hendrik Nogai -Member of the Management Board of the Company as a person dischargingmanagerial responsibilities in the Company, drawn up in relation to thesale of the Company's shares.

The notification is enclosed to this report.Disclaimer: ThisEnglish language translation has been prepared solely for theconvenience of English speaking readers. Despite all the efforts devotedto this translation, certain discrepancies, omissions or approximationsmay exist. In case of any differences between the Polish and the Englishversions, the Polish version shall prevail. Ryvu Therapeutics S.A., itsrepresentatives and employees decline all responsibility in this regard.