RYVU Therapeutics S.A. — Director's Dealing 2022

Dec 22, 2022

The Management Board of Ryvu Therapeutics S.A. with its registeredoffice in Krakow, Poland (_quot;Company_quot;, _quot;Issuer_quot;) hereby informs that theCompany received a notification prepared in accordance with Article 19.1of MAR from Augebit FIZ as from a person closely related to a persondischarging managerial responsibilities in the Company, due to theseries J shares allotment. The notification is attached to this report.