FINANCIAL STATEMENTS RYVU THERAPEUTICS S.A.

prepared for the year from 1 January 2020 to 31 December 2020

for the period 01/01/2020 – 31/12/2020

in accordance with International Financial Reporting Standards as approved by the European Union together with the audit report of an independent statutory auditor

Financial statements of Ryvu Therapeutics S.A. It is the translation of Polish original document

Table of Contents	Page
Statement of comprehensive income	3
Statement of financial position	4
Statement of changes in equity	5
Statement of cash flows	6
Notes to the financial statements	7

Notes to the Interim Financial Statements

1 General information	7
2 International Financial Reporting Standards	9
3 Summary of significant accounting policies	11
4 Significant accounting judgements and estimates	23
5 Sales revenue	26
6 Operating segments	29
7 Finance income	32
8 Finance cost	32
9 Other operating income and expenses	33
10 Income taxes on continuing operations	34
11 Non-current assets held for sale	39
12 Earnings per share	39
13 Tangible fixed assets	40
14 Intangible fixed assets	44
15 Subsidiaries	45
16 Split of the Company	45
17 Valuation of shares in Nodthera	47
18 Financial assets	48
19 Other non-financial assets	49
20 Other financial assets	50
21 Inventories	50
22 Trade and other receivables	51
23 Leases	53
24 Share capital	55
25 First time adoption of IFRS	57
26 Credit facilities and loans and other sources of financing	64
27 Provisions	65
28 Trade and other liabilities	65
29 Liabilities due to retirement benefits	65
30 Financial instruments	66
31 Accrued expenses	73
32 Deferred income	73
33 Related party transactions	74
34 Business combinations	76
35 Cash and cash equivalents	76
36 Average headcount in the Company	76
37 Capital commitments	77
38 Contingent liabilities and assets	77
39 Significant events of the reporting period	77
40 Notes to the statement of cash flow	78
41 Remuneration of the statutory auditor or audit company	79
42 Agreements entered into by the Company and not presented on the balance sheet	79
43 Revenues and costs of R&D own services	79
44 Major events pertaining to prior years and presented in the financial statements for the current year	79
45 Major events after the end of the reporting period which have not been presented in the financial statements	79
46 Subsequent events	79
47 Approval of the financial statements	80

STATEMENT OF COMPREHENSIVE INCOME FOR THE PERIOD FROM 1 JANUARY 2020 TO 31 DECEMBER 2020

	Note	Year ended 31/12/2020	Year ended 31/12/2019
		PLN	PLN
Continuing operations
Sales revenue	5.1	15,650,524	3,798,331
Grant income	5.2	21,300,159	29,921,936
Total operating revenue		36,950,683	33,720,267
Amortization and depreciation	5.5	(12,357,123)	(7,988,635)
Consumption of materials and supplies		(8,764,610)	(12,803,746)
External services	5.5	(24,167,511)	(27,097,536)
Employee benefit expense	5.5	(26,011,968)	(28,400,070)
Employee Capital Plans Other expenses		(327,697) (794,792)	(67,818) (2,776,062)
Taxes and charges		(527,102)	(307,973)
Loss from impairment of trade receivables	22	(26,747)	-
Total operating expenses		(72,977,550)	(79,441,840)
Other operating revenue	9	376,883	418,466
Other operating expenses	9	(47,041)	(82,140)
Operating (loss)		(35,697,025)	(45,385,247)
	7
Financial revenue Financial expenses	8	218,850 (501,357)	906,591 (559,118)
(Loss) on business activities		(35,979,532)	(45,037,774)
Valuation of shares in Nodthera	17	5,363,973	928,380
(Loss) before income tax		(30,615,559)	(44,109,394)
Income tax expense	10	(1,072,029)	(160,890)
Net (loss) on continuing operations		(31,687,588)	(44,270,284)

Discontinued operations		-	329,910,294
(Loss) / net profit on discontinued operations	16	-	611,914
Dividend on discontinued operations	16	-	8,320,928
Profit on spin-off	16	-	320,977,452
NET PROFIT / (LOSS)		(31,687,588)	285,640,010
TOTAL INCOME FOR THE PERIOD		(31,687,588)	285,640,010

Earnings per share
(expressed in PLN cents per share)	12
From continued and discontinued operations:
Basic		(189.0)	1,788.5
Diluted		(189.0)	1,788.5
From continued operations:
Basic		(189.0)	(277.2)
Diluted		(189.0)	(277.2)

STATEMENT OF FINANCIAL POSITION PREPARED AS AT 31 DECEMBER 2020

31/12/2020 31/12/2019 01/01/2019 PLN PLN PLN ASSETS Non-current assets Tangible fixed assets 13 86,672,136 60,279,653 37,278,169 Lease assets 23,13 4,490,175 5,909,828 Intangible fixed assets 14 2,318,534 2,923,654 2,383,664 Deferred tax asset 10 593,525 700,790 - Investment in subsidiaries 15 - - 6,599,616 Financial assets-Shares in Nodthera 17 29,118,228 23,754,255 22,825,875 Other financial assets 20 85,194 85,193 113,579 Total non-current assets 123,277,792 93,653,373 91,028,142 Current assets Inventory 21 1,675,712 1,586,162 1,602,008 Short-term receivables 22 7,948,038 14,680,783 34,449,145 Contract assets 5.3 - 360,205 596,421 Other financial assets 20 24,969,465 - 15,052,998 Other non-financial assets 19 1,551,023 1,242,353 2,162,270 Cash and other monetary assets 35 136,218,238 72,106,927 94,858,075 Total current assets 172,362,476 89,976,430 148,720,917 Total assets 295,640,268 183,629,803 239,749,059 EQUITY AND LIABILITIES Equity Share capital 24 7,342,190 6,388,492 6,388,492 Share premium 24 279,063,058 145,188,585 168,244,820 Capital resulting from the split 16 (14,418,357) (14,418,357) - Capital resulting from the spin-off 16 (320,977,452) (320,977,452) - Other reserve capitals 24 11,172,000 11,172,000 11,172,000 Retained earnings / Accumulated losses 293,226,908 7,586,898 (15,469,337) (Loss) / net result for the period (31,687,588) 285,640,010 - Total equity 223,720,759 120,580,176 170,335,975 Long-term liabilities Bank loans and credits 26 1,552,237 2,362,058 3,171,878 Lease liabilities 23 2,774,589 3,555,985 16,473,609 Retirement provision 29 234,966 188,159 118,023 Deferred tax liability 10 6,042,042 5,143,717 4,430,225 Deferred income 32 27,502,625 21,183,710 10,362,746 Total long-term liabilities 38,106,459 32,433,629 34,556,481 Short-term liabilities Trade and other liabilities 28 11,528,432 22,636,132 20,317,336 Contract liabilities 5.3 - - 759,510 Bank loans and credits 26 814,465 823,750 881,257 Lease liabilities 23 2,267,960 2,474,968 5,597,169 Accrued expenses 31 4,643,230 2,382,595 2,978,966 Deferred income 32 14,558,963 2,298,553 4,322,365 Total short-term liabilities 33,813,050 30,615,998 34,856,603 Total liabilities 71,919,509 63,049,627 69,413,084 Total equity and liabilities 295,640,268 183,629,803 239,749,059	Note	Balance as at	Balance as at	Balance as at





				21,827,239 *

* data as at January 1 and December 31, 2019 have been restated (see Note 13.2)

STATEMENT OF CHANGES IN EQUITY FOR THE REPORTING PERIOD ENDED 31 DECEMBER 2020

	Note	Share capital	Share premium	Capital resulting from the split	Capital resulting from the spin-off	Other reserve capitals	Retained earnings / Accumulated losses	(Loss) / net result for the period	Total
		PLN	PLN	PLN	PLN	PLN	PLN	PLN	PLN
Balance as at 1 January 2019		6,388,492	168,244,820	-	-	11,172,000	(15,469,337)	-	170,335,975
Net profit for the period		-	-	-	-	-	-	285,640,010	285,640,010
Other comprehensive income		-	-	-	-	-	-	-	-
Allocation of the result from		-	(23,056,235)	-	-	-	23,056,235	-	-
previous year
Separation of assets and transfer to	16	-	-	(14,418,357)	(320,977,452)	-	-	-	(335,395,809)
Selvita S.A.
Balance as at 31 December 2019		6,388,492	145,188,585	(14,418,357)	(320,977,452)	11,172,000	7,586,898	285,640,010	120,580,176
Net profit for the period		-	-	-	-	-	-	(31,687,588)	(31,687,588)
Allocation of the result from		-	-	-	-	-	285,640,010	(285,640,010)	-
previous year
Issue of shares		953,698	133,874,473	-	-	-	-		134,828,171
Balance as at 31 December 2020		7,342,190	279,063,058	(14,418,357)	(320,977,452)	11,172,000	293,226,908	(31,687,588)	223,720,759

STATEMENT OF CASH FLOWS

FOR THE PERIOD FROM 1 JANUARY 2020 TO 31 DECEMBER 2020

	Note	Period ended 31/12/2020	Year ended 31/12/2019
		PLN	PLN
Cash flows from operating activities
(Loss) / profit for the period		(31,687,588)	285,640,010
Adjustments:
Valuation of shares in Nodthera		(5,363,973)	(928,380)
Amortization and depreciation and impairment losses on fixed assets		12,357,123	7,988,635
Interest and profit-sharing (dividends), net		(432,089)	(9,145,892)
Profit on the spin-off		-	(320,977,452)
Change in receivables	40	3,743,995	11,672,675
Change in inventories	40	(89,550)	(682,736)
Change in short-term liabilities and provision excluding credits and loans	40	(11,060,893)	(1,088,984)
Change in deferred income	40	20,839,960	14,660,445
Change in deferred tax	40	898,325	(160,890)
Change in other assets	40	158,799	(4,378,395)
Net cash flows from operating activities		(10,635,891)	(17,400,964)
- from continued operations - from discontinued operations		(10,635,891) -	(19,421,795) 2,020,831

Cash flows from investing activities
Disposal of tangible and intangible fixed assets		-	80,000
Purchase of tangible and intangible fixed assets	13	(34,179,581)	(23,994,850)
Purchase / (disposal) of other financial assets	20	(24,969,465)	14,928,600
Acquisition of shares in connection with the spin-off of OPE		2,988,750	(2,988,750)
Dividends received		-	8,320,928
Interest received		218,850	1,042,764
Repayment of loans		-	1,709
Loans granted		-	5,271
Net cash flows from investing activities		(55,941,446)	(2,604,328)
- from continued operations		(55,941,446)	(7,031,859)
- from discontinued operations		-	4,427,531
Cash flows from financing activities
Proceeds from shares issue	24.1	143,054,700	-
Issue costs		(8,226,529)	-
Repayment of finance lease liabilities	23.1	(3,131,314)	(1,704,306)
Proceeds from credits and loans		24,135	57,508
Repayment of credits and loans	40	(819,106)	(881,258)
Dividends paid		-	-
Interest paid
		(213,239)	(217,800)
Net cash flows from financing activities		130,688,647	(2,745,856)
- from continued operations - from discontinued operations		130,688,647 -	(1,629,672) (1,116,184)
Net increase / (decrease) in cash and cash equivalents		64,111,310	(22,751,148)
Cash and cash equivalents at the beginning of the period		72,106,927	94,858,075

Cash and cash equivalents at the end of the period	35	136,218,237	72,106,927

NOTES TO THE FINANCIAL STATEMENTS PREPARED AS AT 31 DECEMBER 2020

1. General information

1.1. The company

Ryvu Therapeutics S.A. was established as a result of the transformation of Selvita Spółka z o.o. in a joint-stock company based on the Notarial Deed of August 20, 2010 prepared at the notary's office A. Deflorian, D. Jastrzębska-Kwiecień Spółka Cywilna (Rep. No. 3222/2010). The registered office of the company is in Poland, Cracow, Bobrzyńskiego Street 4. Currently, the Company is registered in the Register of Entrepreneurs of the National Court Register at the District Court for the city of Kraków - Śródmieście - XI Economic Department under the KRS number 0000367359.

Composition of the management and supervisory bodies as at the date of these financial statements:

Management Board:
Paweł Tadeusz Przewięźlikowski	-	President of the Management Board
Krzysztof Daniel Brzózka	-	Vice-President of the Management Board
Setareh Gharayagh Shamsili	-	Vice-President of the Management Board
Kamil Sebastian Sitarz -		Member of the Management Board
Supervisory Board:
Piotr Romanowski	-	Chairman
Tadeusz Wesołowski	-	Vice- Chairman
Rafał Piotr Chwast	-	Member
Axel Glasmacher	-	Member
Colin Goddard	-	Member
Jarl Jungnelius	-	Member
Thomas Turalski	-	Member

As at December 31, 2020 the shareholder structure of the company is as follows:

	Registered office	Number of shares	Percentage interest in capital	Percentage share in voting rights
Paweł Tadeusz Przewięźlikowski	Poland	4,990,880	27.19%	37.90%
Bogusław Stanisław Sieczkowski	Poland	924,384	5.04%	6.58%
Nationale -Nederlanden Open-End Pension
Fund and Nationale - Nederlanden Voluntary	Poland	1,594,749	8.68%	7.11%
Pension Fund *
Other shareholders		10,845,461	59.09%	48.41%
Razem		18,355,474	100.00%	100.00%

* the state resulting from the subscription to the Ordinary General Meeting of the Issuer, which took place on August 31, 2020.

As of December 31, 2019, the shareholding structure of the Company was as follows:

	Registered office	Number of shares	Percentage interest in capital	Percentage share in voting rights
Paweł Tadeusz Przewięźlikowski	Poland	4,990,880	31.25%	42.41%
Bogusław Stanisław Sieczkowski Augebit Fundusz investment closed (directly	Poland	924,384	5.79%	7.36%
and indirectly through Privatech Holdings	Poland	1,039,738	6.51%	5.19%
Limited) * Nationale-Nederlanden Otwarty Fundusz
Emerytalny Other shareholders (less than 5% of votes at	Poland	1,594,749	9.99% 46.46%	7.97%
the GM)		7,421,478		37.07%
Razem		15,971,229	100.00%	100.00%

* the beneficiary of Augebit FIZ is Tadeusz Wesołowski - Vice-Chairman of the Supervisory Board

The duration of the Company is not fixed.

The calendar year is the financial year of the Company.

The core business of the Capital Company comprises research and development in biotechnology.

1.2. Going concern assumption

The Company's financial statements have been prepared on the assumption that the Company will continue as a going concern for at least 12 months after the balance sheet date, i.e. after December 31, 2020.

Covid-19 pandemic began in the first quarter of 2020 and continued (and still continues) during the whole reported period. Because of that the Issuer implemented the recommendations given by the Chief Sanitary Inspectorate and other government institutions in connection with the epidemiological threat, including the implementation of remote work and ensuring safe working conditions for stationary employees. Moreover, business trips to the countries which the Chief Sanitary Inspectorate defined as high-risk countries, were suspended. The Issuer used remote communication in its business contacts. Furthermore, the Issuer appointed a working team consisting of the representatives of various organizational units, whose task is to respond to the situation on an ongoing basis and mitigate any adverse effects of the spread of the epidemic on the Issuer. The Company also developed its internal policy for preventing the spread of the coronavirus and taking actions aimed at ensuring appropriate health and safety conditions at work. These documents are constantly updated and adapted to the latest guidelines and changing conditions.

Because of the pandemic situation in the US. Ryvu management has decided to start the European arm of the study earlier than originally expected and include additional sites in Poland and other European countries. The first in Europe Clinical Trial Application (CTA) was submitted on August 11, 2020. At the beginning of January 2021 Ryvu Polish Office for Registration of Medicinal Products, Medical Devices and Biocidal Products, and the respective Central Ethics Committee approved Ryvus CTA to commence SEL120 clinical trial in clinical centres in Poland. More information on the research and development activities conducted by the Issuer and their current status is disclosed in point 2.1 of the Management Report on the activities of Ryvu Therapeutics S.A. for the financial year 2020.

In addition, on August 18, 2020, the District Court for Kraków-Śródmieście in Kraków, XI Commercial Division of the National Court Register, registered an increase in the Company's share capital from PLN 6,388,491.60 to PLN 7,342,189.60 through an issue series I ordinary bearer shares of the Company with a nominal value of PLN 0.40 each. The issue price of the Series I Shares was set at PLN 60 per share, therefore the total proceeds from the issue, understood as the product of the number of shares covered by the offering and the issue price, amounted to PLN 143,054,700, and the total costs of the offering were PLN 8,226,529. More information on the above subject is provided in Note 24.1 to the financial statements.

In addition, as described in note 46 of the financial statements, on January 18, 2021, the Company was recommended for funding by the National Center for Research and Development (NCBiR) for the Issuer's project on clinical testing of the SEL120 / RVU120 (RVU120) molecule in solid tumors.

Due to the negative impact of Covid-19 on global economies, Covid-19 is expected to be a threat to the entity, but due to the mitigating measures taken and the events listed above and the specific nature of the business (industry in which the Company operates), the Management Board of the Company believes that the pandemic had no significant impact on the achievement of revenues, including subsidies, or financial liquidity. The Management Board does not see any significant uncertainty related to the going concern status.

1.3. Functional and reporting currency

These financial statements have been prepared in the Polish zloty (PLN). The Polish zloty is the functional and reporting currency of the Company. Figures in the financial statements are expressed in full Polish zlotys unless it is otherwise stated.

2. International Financial Reporting Standards

2.1. Statement of compliance

These separate financial statements have been prepared in accordance with the International Financial Reporting Standards ("IFRS") approved by the European Union ("IFRS EU"). As at the date of approval of this report for publication, taking into account the ongoing process of introducing IFRS in the European Union, the IFRS applicable to this financial statement do not differ from EU IFRS.

IFRS EU include standards and interpretations approved by the International Accounting Standards Board ("IASB").

On June 4, 2020, in accordance with art. 45.1b of the Accounting Act, the Extraordinary General Meeting of Shareholders adopted a resolution to change the accounting principles applied by the Company and start preparing financial statements in accordance with the International Financial Reporting Standards (IFRS) and related interpretations published in the form of regulations of the European Commission, starting from the Company's financial statements prepared for the period of three months ended on March 31, 2020, due to the fact that the financial statements prepared in accordance with IFRS will be more readable and useful for investors, especially foreign investors. This will also ensure the comparability of the Company's financial data with entities operating in the biotechnology industry, which in the vast majority carry out financial reporting in accordance with IFRS.

These separate financial statements prepared for the period from 1 January 2020 to 31 December 2020 are the first yearly financial statements containing disclosures in accordance with the International Financial Reporting Standards approved by the EU (hereinafter referred to as "IFRS"), in particular with IFRS 1.

Reconciliation of the Company's capital as at January 1, 2019 and December 31, 2019, reconciliation of the Company's total income for the year ended December 31, 2019, and reconciliation of cash flows for the year ended December 31, 2019 were presented in note 25 'First-time adoption of IFRS'

The company applied IFRS according to the status as at December 31, 2020. The company applied identical accounting principles (policy) to the preparation of the opening balance sheet according to IFRS as at January 1, 2019 and throughout all the periods presented in this report. All changes in accounting policies were introduced retrospectively, with the exception of the following exemptions permitted by IFRS 1. listed in note 25. The last available, as at the date of approval of these financial statements, financial statements of the Company prepared in accordance with Polish accounting principles, as defined in the Accounting Act of 29 September 1994 (consolidated text Journal of Laws 2019.351, as amended), is the financial statement prepared for year ended December 31, 2019.

When preparing these financial statements, the opening report on the Company's financial standing was prepared and presented as at January 1, 2019, i.e. as at the date of the Company's transition to IFRS in accordance with the resolution of the Extraordinary General Meeting of Ryvu Therapeutics S.A. on the transition to IFRS of 4 June 2020.

2.1.1. Reporting period and scope

The Company's financial statements cover the financial period from 1 January 2020 to 31 December 2020 and contain comparative data that constitute data for the financial period from 1 January 2019 to 31 December 2019. The statement of financial position and explanatory notes to this report also contain comparative data as at January 1, 2019, constituting the date of the Company's transition to IFRS.

Status of IFRS endorsement by the EU

2.2. The following standards and interpretations have been published by the International Accounting Standards Board, but they do not apply to these financial statements (i.e. for 12-months financial statements ended December 31, 2020)

• IFRS 14 Regulatory Deferral Accounts (published on January 30, 2014) - in accordance with the decision of the European Commission, the approval process of the standard in its draft version will not be initiated before the publication of the final version - until the date of approval of these financial statements, not approved by the EU - applicable to annual periods beginning on or after January 1, 2016;

• Amendments to IFRS 10 and IAS 28: Transactions of sale or contribution of assets between the investor and its associate or joint venture (published on September 11, 2014) - the work leading to the approval of these amendments has been postponed indefinitely by the EU - the effective date has been postponed by the IASB for an indefinite period;

• IFRS 17 Insurance Contracts (published on May 18, 2017) - not approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on or after January 1, 2021;

• Amendments to IAS 1: Presentation of financial statements - Division of liabilities into short-term and long-term (published on January 23, 2020) - not

approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on January 1, 2022 or later;

• Amendments to IFRS 3 Amendments to references to the Conceptual Framework (published on May 14, 2020) - not approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on or after January 1, 2022;

• Amendments to IAS 16 Property, plant and equipment: revenues achieved before putting into use (published on May 14, 2020) - not approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on January 1, 2022 or later;

• Amendments to IAS 37 Onerous Contracts - Costs of Meeting Contractual Obligations (published on May 14, 2020) - not approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on or after January 1, 2022;

• Amendments resulting from the review of IFRS 2018-2020 (published on May 14, 2020) - not approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on or after January 1, 2022;

• Amendments to IFRS 4: Insurance contracts - deferral of IFRS 9 (published on June 25, 2020) - applicable to annual periods beginning on or after January 1, 2021;

• Amendments to IFRS 9, IAS 39, IFRS 7, IFRS 4 and IFRS 16: Reform of interest rate benchmarks - Phase 2 (published on August 27, 2020) - applicable to annual periods beginning on January 1, 2021 or later;

• Amendments to IAS 1 and Practice Statement 2: Disclosure of information regarding accounting principles (policy) (published on February 12, 2021) - not approved by the EU until the date of approval of these financial statements - applicable to annual periods beginning on January 1, 2023 or later;

• Amendments to IAS 8: Definition of Accounting Estimates (published on February 12, 2021) - until the date of approval of these financial statements, not approved by the EU - applicable to annual periods beginning on or after January 1, 2023.

The dates of entry into force are the dates resulting from the content of the standards announced by the International Financial Reporting Council. The dates of application of the standards in the European Union may differ from the dates of application arising from the content of the standards and are announced at the time of approval for use by the European Union.

Amendments to IFRS 16 Leasing (published on May 28, 2020) - until the date of approval of these financial statements, not approved by the EU - applicable to annual periods beginning on June 1, 2020 or later.

3. Summary of significant accounting policies

3.1. Going concern

The financial statements have been prepared on the assumption that the company will continue as a going concern in the 12 months following the end of the reported period, i.e. December 31, 2021. The issue of going concern was presented in Note 1.2.

3.2. Basis of preparation

The financial statements have been prepared in accordance with the historical cost concept, except for shares in Nodthera, which are measured at fair value.

The key accounting principles used by the Company have been presented below.

3.3. Investments in associates

Not applicable.

3.4. Interests in joint ventures

Not applicable.

3.5. Non-current assets held for sale

Not applicable.

3.6. Revenue recognition

3.6.1. Grants

Subsidies are recognized in accordance with IAS 20. Subsidies are not recognized until there is reasonable certainty that the Company will meet the necessary conditions and will receive such subsidies, government subsidies are recognized at their fair value as deferred income.

Government subsidies for a given cost item are recognized as revenue from subsidies systematically, for each period in which the Company recognizes expenses as costs, the compensation of which is to be a subsidy.

If the subsidy relates to an asset, then its fair value is recognized as deferred income, and then gradually, through equal annual write-offs, recognized in the income from the subsidy over the estimated useful life of the related asset.

Two types of subsidy are awarded: research subsidies and infrastructure subsidies.

In research grants, eligible costs may be the remuneration of employees related to co-financed projects, external services, depreciation of equipment, etc. Revenue from subsidies is calculated in proportion to the eligible costs incurred, the co-financing ratio in accordance with the signed grant agreement.If, under the subsidy, the Company is entitled to a bonus, e.g. due to publication of the results of work, the Management Board of the Company each time assesses whether there is reasonable certainty that the conditions for obtaining the bonus are met, and if there is such justified certainty, it recognizes the revenue from the subsidy, taking into account the Company's right.

The purchase of fixed assets is co-financed in infrastructural subsidies. Revenue from subsidies is calculated in proportion to the depreciation costs, co-financing rate in accordance with the signed subsidy agreement. Accrued income from subsidies is refereed to other receivables (receivables from subsidies). Cash that flows into the bank account is referred to deferred income.

3.6.2. Sales of goods and services

Revenues, except for subsidies, are recognized in accordance with IFRS 15, the Company recognizes revenue in a manner that presents the transaction of transferring to the customer promised goods or services, in the amount reflecting the value of remuneration that the Company expects in exchange for these goods or services. In view of the above, it is crucial to correctly determine the moment and amount of revenue recognized by the Company.

The standard introduced the following unified 5-stage revenue recognition model:

Stage 1: Identification of the contract with the client,
Stage 2: Identification of the performance obligations contained in the contract,
Stage 3: Determining the transaction price,
Stage 4: Allocation of the transaction price to the performance obligations contained in the contract,
Stage 5: Income recognition when the performance obligation is met (or being met).

Pursuant to IFRS 15, the Company recognizes revenue when the performance obligation is met (or being met), i.e. when the control over the goods or services that are the subject of the obligation is transferred to the customer. Revenues are recognized as amounts equal to the transaction price that has been assigned to the given performance obligation.

The Company transfers control over a good or service over time and thus meets the obligation to provide a service and recognizes revenue over time if one of the following conditions is met:

the customer simultaneously receives and receives benefits from the service as it is performed,
an asset is created or improved as a result of the performance of the service, and the control over that asset - as the customer creates or improves it, - as a result of the performance of the service, no alternative component is created for the Company, and the Company has an enforceable right to pay for the service performed so far.

To measure the degree of total fulfillment of the obligation to perform the performance met over time the Company uses a results-based method, i.e. it recognizes revenues on the basis of a direct measurement of the value for the client of goods and services that have so far been transferred to the client, in relation to the other goods or services promised in the contract, by assessing the results achieved and the stages.

When it is probable that total contract costs exceed total contract revenue, the expected loss is recognized immediately in costs and accounted for in accordance with IAS 37.

The amounts received before carrying out the works to which they relate are recognized in the statement of financial position in liabilities as liabilities under contracts. The amounts invoiced for completed works, but not yet paid by customers, are recognized in the statement of financial position in trade receivables and in net profit.

The Company receives part of the remuneration in advance when signing the contract due to the signed contracts for the sale of R&D projects, and is also authorized to receive further payments in the event of successful development and commercialization of a potential drug that will be created based on the results of cooperation. In addition, the Company is guaranteed royalties on the sale of products developed as a result of cooperation.

3.7. Interest and dividend income

Dividend income is recognized at the record date (provided that it is probable that the Company will derive economic benefits and the income may be measured reliably).

Interest income is prorated with respect to the outstanding principal using the effective interest method, which is the rate used for discounting future cash flows over the useful life of a financial asset to its carrying amount on initial recognition.

3.8. Leases Assets due to the right of use The Company as a lessee

The Company recognizes assets due to the right to use on the lease commencement date (ie the date when the underlying asset is available for use). Assets under the right to use are valued at cost, less total depreciation and impairment losses, adjusted for any revaluation of lease liabilities. The cost of assets due to the right to use includes the amount of lease liabilities recognized, initial direct costs incurred and any lease payments paid on or before the start date, less any leasing incentives received. Unless the Company has sufficient assurance that it will obtain ownership of the subject of the lease at the end of the lease period, the recognized rights under usufruct rights are amortized using the straight-line method over the shorter of the two periods: estimated useful life or lease period. Assets under the right to use are subject to impairment.

Lease liabilities

At the start of the lease, the Company measures the lease liabilities in the amount of the current value of the lease payments remaining on that date. Leasing fees include fixed fees (including essentially fixed leasing fees) less any leasing incentives due, variable fees that depend on the index or rate, and amounts expected to be paid under the guaranteed final value. Lease payments also include the price of the call option if it can be assumed with sufficient certainty that the Company will exercise it and payment of fines for termination of the lease, if the lease conditions provide for the possibility of the lease being terminated by the Company. Variable lease payments that do not depend on an index or rate are recognized as costs in the period in which the event or condition giving rise to the payment occurs.

When calculating the current value of lease payments, the Company uses the lessee's marginal interest rate on the day the lease starts, if the leasing interest rate cannot be easily determined. After the start date, the amount of the lease liability is increased to reflect interest and reduced by the lease payments made. In addition, the carrying amount of lease liabilities is re-measured if the lease period changes, the lease payments change substantially or the judgment regarding the purchase of underlying assets changes.

Short-term leasing and leasing of low-value assets

The Company applies the exemption from recognizing short-term leases to its short-term lease contracts (i.e. contracts whose lease period is 12 months or less from the commencement date and does not include a call option). The Company also applies an exemption regarding the recognition of leases of low-value assets in relation to low-value leases i.e. up to USD 5 thousand. Leasing fees for short-term leasing and leasing of low-value assets are recognized as costs using the straight-line method over the duration of the lease.

Significant judgments and estimates were described in the Note 4.1.

3.9. Foreign currencies

Transactions in currencies other than the functional currency (foreign currency transactions) are presented at the exchange rate ruling at the transaction date. As at the end of the reporting period, monetary assets and liabilities denominated in foreign currencies are translated at the exchange rate ruling as at that date. Non-monetary items measured at fair value and denominated in foreign currencies are measured at the exchange rate effective as at the date of fair value measurement. Non-monetary items are measured at historical cost.

Exchange differences on monetary items are recognized in profit or loss for the period when they occur, except exchange differences on assets under construction intended to be used for manufacturing purposes in the future, which increase the cost of such assets and are treated as adjustment to interest expense related to foreign currency loans.

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
EUR / PLN	4.6148	4.2585	4.3000
USD / PLN	3.7584	3.7977	3.7597
GBP / PLN	5.1327	4.9971	4.7895
CHF / PLN	4.2641	3.9213	3.8166
JPY / PLN	0.0365	0.0350	0.0341
SEK / PLN	0.4598	0.4073	0.4201

3.10. Borrowing costs

Borrowing costs directly related to the acquisition or production of assets that require a longer time to bring them to use are included in the costs of producing such assets until they are generally ready for their intended use or sale. In the reporting period, the issue did not occur.

Revenue from investments obtained as a result of short-term investment of acquired external funds allocated directly to finance the purchase or production of assets reduce the value of borrowing costs subject to capitalization. In the reporting period, the issue did not occur.

All other borrowing costs are charged directly to the result in the period in which they were incurred.

3.11. Costs of employee benefits and contract termination

Provisions for employee benefits, i.e. retirement benefits, are estimated at the end of each reporting period using simplified methods similar to actuarial ones.

3.12. Taxes

The entity's income taxes comprise current and deferred tax.

3.12.1. Current tax

The current tax liability is measured on the basis of the taxable profit or loss (tax base) for the reporting period. The taxable profit (loss) differs from the accounting profit (loss) due to elimination of revenue that is temporarily not taxable and temporarily non-deductible expenses as well as expenses and revenue which will never be subject to tax. The tax charge is determined using the tax rates effective in the financial year.

3.12.2. Deferred tax

Deferred tax is recognized with respect to temporary differences between the carrying amount of assets and liabilities in the financial statements and the corresponding tax base used for purposes of calculation of taxable profit, as well as unused tax losses and unused tax credits. As a rule, the deferred tax liability is recognized for all temporary taxable differences. A deferred tax asset is recognized with respect to all temporary deductible differences insofar as it is probable that the entity will generate taxable profit against which such differences may be offset. Such deferred tax asset and liability is not recognized if the temporary differences arise from goodwill or from initial recognition (except business combinations) of other assets and liabilities in a transaction which does not affect the tax or accounting profit.

The value of the deferred tax asset is reviewed at the end of each reporting period and if the expected future taxable profit is insufficient to realize the asset or its part, an impairment loss is recognized as appropriate.

Deferred tax is calculated using tax rates that will apply when the asset is realized or the liability becomes due. The valuation of deferred tax reserves and deferred tax assets reflects the tax consequences that will occur in line with the manner of implementation or settlement of balance sheet assets and liabilities as forecast by the Company. A significant part of the recognized deferred tax asset is expected to be realized over the next 12 months (as it relates to short-term provisions).

In the area of income tax, the Company is subject to general provisions in this area, these are basically the Polish provisions of the CIT Act and associated provisions. The company is not a tax capital Company. The tax and balance sheet years coincide with the calendar year.

The company recognizes a deferred tax asset that is used to carry over unused tax losses to the extent that it is probable that future taxable income will be available against which unused tax losses can be deducted. In assessing whether it is likely that the future taxable income available will be sufficient, the Company takes into account the nature, origin and timing of such income and ensures that convincing evidence is collected. The company assesses the realizability of the deferred tax asset as at each balance sheet date. This assessment requires the involvement of professional judgment and estimates, including regarding future tax results. An unrecognized deferred tax asset is subject to reassessment at each balance sheet date and is recognized up to the amount that reflects the probability of achieving taxable income in the future that will allow recovery of that asset.

Uncertainty associated with the recognition of income tax

Pursuant to IFRIC 23, if in the Company's opinion it is likely that the Company's approach to a tax issue or Company of tax issues will be accepted by the tax authority, the Company determines taxable income (tax loss), tax base, unused tax losses, unused tax credits and rates tax including the approach to taxation planned or used in your tax return. Assessing this probability, the Company assumes that the tax authorities authorized to inspect and challenge the tax treatment will carry out such an inspection and will have access to all information. If the Company determines that it is not probable that the tax authority will accept the Company's approach to a tax issue or Company of tax issues, then the Company reflects the effects of uncertainty in accounting terms of tax in the period in which it determined it. Therefore, the company recognizes an income tax liability using one of the following two methods, depending on which of them better reflects the way in which uncertainty can materialize:

The company determines the most likely scenario - this is a single amount among the possible outcomes or
The company recognizes the expected value - it is the sum of probability weighted amounts among the possible results.

3.12.3. Current and deferred tax for the period

The current and deferred tax is recognized in profit or loss, except for items recognized in other comprehensive income or directly in equity. In such a case, the current and deferred tax is also charged to other comprehensive income or equity, respectively. If the current or deferred tax results from initial recognition of a business combination, the tax effect is taken into consideration in the subsequent entries related to that business combination.

3.13. Property, plant and equipment

Fixed assets are measured at cost or revalued amounts less depreciation and impairment losses.

Costs incurred after a fixed asset has been commissioned, such as costs of repairs, inspections or maintenance fees, are recognized in profit or loss for the period during which they were incurred. However, where it may be proven that the said costs resulted in an increase of the expected future economic benefits related to holding the asset above those assumed initially, they increase the initial value of the fixed asset. Where the payment for fixed assets purchased by the Company is made in a foreign currency, the initial value is not increased by exchange differences.

Fixed assets under construction are measured at total cost related directly to their acquisition or manufacturing, including financial expenses, less impairment losses. Fixed assets under construction include payments of patent fees related to research.

Fixed assets, except land and the right of perpetual usufruct of land, are depreciated on a straight-line basis over the period of their estimated useful life or the shorter of the useful life or the period of the right to use the assets, which is as follows:

building, premises, civil and water engineering structures from 10 to 40 years;
technical equipment and machines 3-10 years;
vehicles 5 years;
other fixed assets 3-5 years.

Machines and equipment are recognized at cost less depreciation and accumulated impairment losses.

Depreciation is recognized so as to reduce the cost or the measurement of an asset (other than land and fixed assets under construction) to its residual value using the straight-line method. The estimated useful lives, residual values and depreciation methods are reviewed at the end of each reporting period (with prospective application of all changes in estimates).

An item of property, plant and equipment is derecognized from the balance sheet upon its disposal or when it is expected that no further economic benefits will flow to the entity in relation to its use. Any gains or losses resulting from disposal of an item of property, plant and equipment or its decommissioning are charged to profit or loss for the period when the item was derecognized (calculated as the difference between proceeds from sale and the carrying amount of the asset).

3.14. Intangible assets

3.14.1. Intangible assets

Intangible assets with fixed useful life, purchased by the Company, are recognized at cost less amortization and accumulated impairment losses. Amortization is recognized on a straight-line basis over the estimated useful life. The estimated useful life and amortization method are reviewed at the end of each reporting period and the effects of changes in the estimates are accounted for prospectively. Intangible assets with indefinite useful life, purchased by the Company, are recognized at cost less accumulated impairment losses.

3.14.2. Intangible assets developed internally – R&D cost

R&D cost is recognized in profit or loss when incurred.

Intangible assets developed as a result of R&D work are recognized in the statement of financial position only if the Company has:

the technical feasibility of completing the intangible asset so that it will be available for use or sale;
the intention to complete the intangible asset and use or sell it;
the ability to use or sell the intangible asset;
knowledge of how the intangible asset will generate future economic benefits;
access to adequate technical and financial resources to complete the development and to use or sell the intangible asset;
the ability to measure reliably the expenditure attributable to the intangible asset during its development.

The initial value of internally developed intangible assets is the total of expenses incurred from the date at which the asset satisfied the above recognition criteria for the first time. If internal R&D cost cannot be recognized on the balance sheet, it is charged to profit or loss for the period in which it was incurred.

After initial recognition, an intangible asset developed internally is carried at cost less accumulated amortization and accumulated impairment losses, in line with the principles applicable to intangible assets purchased by the entity.

3.14.3. Derecognition of intangible assets

An intangible asset is derecognized on disposal or when no future economic benefits are expected from its use or disposal. Any gains or losses arising from derecognition of an intangible asset from the balance sheet (determined as the difference between proceeds from sale and the carrying amount of the asset) are recognized in profit or loss for the period when the asset was derecognized.

3.15. Impairment of property, plant and equipment and intangible assets, except goodwill

At the end of each reporting period, the Company reviews the carrying amounts of its property, plant and equipment and intangible assets in order to determine whether there are any indications of impairment. If such indications are identified, the recoverable amount of the asset is estimated in order to determine the value of the potential impairment loss. Where the recoverable amount of an asset may not be estimated, an analysis of the recoverable amount is performed for the cash generating unit which the asset has been allocated to. Where a reliable and consistent basis for allocation can be identified, the Company's non-current assets are allocated to individual cash generating units or to the smallest Companys of cash generating units for which a reliable and consistent allocation basis can be identified.

Intangible assets with indefinite useful lives or those which have not been commissioned yet are tested for impairment annually and additionally whenever indications of their impairment are identified.

The recoverable amount is determined as the higher of the fair value less costs to sell or the value in use. The value in use is the present value of the projected future cash flows discounted using a pre-tax rate that reflects current market assessments of the time value of money and the risks specific to the asset.

If the recoverable amount of an asset (or cash generating unit) is lower than its carrying amount, the carrying amount of the asset (or cash generating unit) is reduced to its recoverable amount. An impairment loss is recognized immediately in profit or loss of the period in which impairment was identified.

Where an impairment loss is subsequently reversed, the net value of the asset (or a cash generating unit) is increased to the revised estimate of the recoverable amount, which, however, may not exceed the carrying amount of the asset which would have been determined had an impairment loss of the asset/cash generating unit not been recognized in previous years. Reversal of an impairment loss is recognized immediately in profit or loss.

3.16. Inventories

Inventories are measured at the lower of cost or realizable value. The cost of inventories is determined using the FIFO method. The realizable value is the estimated sale price of inventories less any estimated costs necessary to complete the manufacturing process/provide a service or to complete the sale transaction.

Purchased materials are recognized directly in operating expenses and measured at the end of the reporting period in line with the aforementioned principles based on a physical inventory.

The Company's inventories are reagents and laboratory materials used in research.

3.17. Provisions

Provisions are recognized when the Company has a present obligation (legal or constructive) as a result of a past event, it is probable that an outflow of resources embodying economic benefits will be required to settle the obligation and a reliable estimate can be made of the amount of the obligation.

The amount recognized as a provision is the best estimate of the amount required to fulfil the present obligation at the end of the reporting period, taking into account the risks and uncertainties related to the obligation. Where a provision is measured using the method of projected cash flows required to fulfil the present obligation, the carrying amount corresponds to the present value of such cash flows (if the effect of the time value of money is material).

When some or all of the economic benefits required to settle the provision are expected to be recovered from a third party, the amount due is recognized as an asset if it is almost certain that the amount will be recovered and it can be measured reliably.

3.17.1. Onerous contracts

Current liabilities under onerous contracts are recognized and measured as provisions. An onerous contract is a contract entered into by the Company, in which the unavoidable costs of meeting the obligations under the contract exceed the economic benefits expected to be received under it.

3.17.2. Restructuring

A restructuring reserve is recognized only where the Company has developed a detailed and formal restructuring plan and announced its intention to implement the plan or achieve its key objectives to all the parties concerned. The restructuring reserve comprises only direct restructuring costs, that is such amounts as may be necessary to carry out the restructuring project, which are not related to the day-to-day running of the business.

3.18. Cash and cash equivalents

Cash and short-term deposits shown in the balance sheet include cash at bank and in hand, cash at bank on split payment account and short-term deposits with the original maturity of up to three months.

The balance of cash and cash equivalents disclosed in the statement of cash flows consists of the above-mentioned cash and cash equivalents, less outstanding loans in current accounts.

3.19. Financial instruments

3.19.1. Classification and initial recognition of financial instruments

The Company assigns financial instruments in accordance with the IFRS 9 to one of three categories:

• measured on the basis of the amortized cost,

• measured at fair value through other total income,

• measured at fair value through profit or loss.

The classification depends on the business model used by an entity with respect to financial asset management and on whether cash flows arising from the contracts include solely the payments of principal and interest ('SPPI').

• If a financial instrument is maintained in order to generate cash flow, it is classified as measured based on the amortised cost, provided that it meets the SPPI requirement.

• Debt instruments meeting the SPPI requirement, maintained both in order to generate contractual cash flows arising from assets and to sell assets, are classified as measured at fair value through other total income.

• All other debt instruments are measured at fair value, where the results of measurement are recognised in the financial result.

Financial liabilities and financial assets, excluding trade receivables which do not contain a significant financing component, are measured at fair value during the initial recognition.

Trade receivables that do not contain a significant financing component are measured at the transaction value during the initial recognition.

Cessation of recognition

Financial assets are excluded from the books of accounts when:

• the rights to obtain cash flows from financial assets have expired, or

• the rights to obtain cash flows from financial assets have been transferred and the Company has transferred substantially all risks and rewards of ownership.

Valuation after initial recognition

For the purpose of valuation after initial recognition, financial assets are classified into one of four categories:

debt instruments measured at amortized cost,
debt instruments measured at fair value through other comprehensive income,
equity instruments measured at fair value through other comprehensive income,
financial assets at fair value through profit or loss.

Financial assets measured at amortized cost

A financial asset is measured at amortized cost if both of the following conditions are met:

(a) the financial asset is held in accordance with a business model whose purpose is to hold financial assets for obtaining contractual cash flows, and

(b) the terms of the contract relating to the financial asset give rise to cash flows on certain dates that are only repayment of principal and interest on the principal amount outstanding.

The Company classifies into the category of financial assets measured at amortized cost:

• trade receivables,

• loans granted that meet the SPPI classification test and which, according to the business model, are shown as held to obtain cash flows,

cash and cash equivalents,
bonds issued by renowned Polish financial entities.

Trade and other receivables and other receivables

Receivables from sales of goods and services are recognized and disclosed according to the initially invoiced amounts, taking into account the writedown for expected credit losses in the entire lifetime.

If the effect of the time value of money is material, the value of receivables is determined by discounting the projected future cash flows to the present value using a discount rate that reflects current market assessments of the time value of money. If the discounting method was used, the increase in receivables due to the passage of time is recognized as financial income.

Other receivables include, in particular, advance payments for future purchases of property, plant and equipment, intangible assets and inventories. Advances are presented in accordance with the nature of the assets to which they relate - as fixed or current assets, respectively. Advances as nonmonetary assets are not discounted.

Budget receivables are presented as other non-financial assets, with the exception of corporate income tax receivables, which constitute a separate item on the balance sheet.

Financial assets at fair value through other comprehensive income

A financial asset is measured at fair value through other comprehensive income, if both of the following conditions are met:

(a) the financial asset is held in accordance with a business model whose purpose is both to receive contractual cash flows and to sell financial assets; and

(b) the terms of the contract relating to the financial asset give rise to cash flows on certain dates that are only repayment of principal and interest on the principal amount outstanding.

Interest income, exchange rate differences and impairment gains and losses are recognized in profit or loss and calculated in the same way as for financial assets measured at amortized cost. Other changes in fair value are recognized in other comprehensive income. When the financial asset is discontinued, the total profit or loss previously recognized in other comprehensive income is reclassified from equity to profit or loss.

Interest income is calculated using the effective interest method and is recognized in the statement of comprehensive income under 'Interest income'.

The Company classifies listed debt instruments to the category of debt instruments valued at fair value through other comprehensive income.

Financial assets at fair value through other comprehensive income

At the time of initial recognition, the Company may make an irrevocable choice regarding the recognition in subsequent comprehensive income of subsequent changes in the fair value of an investment in an equity instrument that is not held for trading or is not a conditional consideration recognized by the acquirer in a business combination to which IFRS 3 applies. Such selection is made separately for each equity instrument. Accumulated gains or losses previously recognized in other comprehensive income are not reclassified to profit or loss. Dividends are recognized in the statement of comprehensive income when the entity's entitlement to receive dividends arises, unless those dividends are obviously recovering part of the investment costs.

The Company classifies unlisted equity instruments as equity instruments measured at fair value through other comprehensive income.

Financial assets at fair value through profit or loss

Financial assets that are not measured at amortized cost or at fair value through other comprehensive income are measured at fair value through profit or loss.

The Company classifies listed equity instruments as financial assets at fair value through profit or loss.

Profit or loss on the measurement of these assets at fair value is recognized in profit or loss.

Dividends are recognized in the statement of comprehensive income when the entity's entitlement to receive dividends arises.

Trade and other liabilities

Short-term liabilities due to deliveries and services are shown in the amount requiring payment.

Financial liabilities at fair value through profit or loss include financial liabilities held for trading and financial liabilities initially classified as at fair value through profit or loss. Financial liabilities are classified as held for trading if they were acquired for the purpose of sale in the near future. Derivatives, including separated embedded derivatives, are also classified as held for trading unless they are recognized as effective hedging instruments.

As at December 31, 2020, no financial liabilities have been classified as measured at fair value through profit or loss.

Financial liabilities measured at fair value through profit or loss are measured at fair value, taking into account their market value as at the balance sheet date, excluding sales transaction costs. Changes in the fair value of these instruments are recognized in profit or loss as financial costs or revenues, except for changes due to own credit risk for financial liabilities initially classified as at fair value through profit or loss, which is recognized in other comprehensive income.

Other financial liabilities that are not financial instruments at fair value through profit or loss are measured at amortized cost using the effective interest method.

The company excludes from its balance sheet a financial liability when the liability has expired - that is, when the obligation specified in the contract has been fulfilled, canceled or has expired.

Other non-financial liabilities include, in particular, liabilities to the tax office due to value added tax and liabilities due to advance payments received, which will be settled by the delivery of goods, services or fixed assets. Other non-financial liabilities are recognized at the amount requiring payment.

Interest-bearing bank loans, loans and debt securities

At initial recognition, all bank loans, borrowings and debt securities are recognized at fair value, less costs associated with obtaining the loan.

After initial recognition, interest-bearing loans, borrowings and debt securities are measured at amortized cost using the effective interest method.

When determining the amortized cost, account is taken of the costs associated with obtaining the loan or borrowing as well as discounts or premiums obtained in connection with the liability.

Income and expenses are recognized in profit or loss when the liability is removed from the balance sheet, as well as as a result of settlement using the effective interest rate method.

3.19.2. Impairment of financial instruments

At the end of each fiscal year, the Company carries out the analysis of financial instruments in order to determine their impairment and prepare an impairment loss.

To this end, the Company applies the impairment model based on expected credit losses, as a result of which the impairment loss is recognised before the occurrence of credit loss. This model requires taking into account both the current conditions as well as reasonable and documented information concerning the future, available without excessive costs and efforts, in the process of calculating the expected credit loss.

Two approaches are used for the estimation of financial instrument impairment losses:

• General approach – applied to financial assets measured at fair value through other total income and to financial assets measured at the amortised cost, excluding trade receivables.

• Simplified approach – applied to trade receivables and contract assets that do not include a significant financing element. The Company calculates the expected credit loss in the entire life cycle for this category of assets with the use of a provision matrix. The calculation is based on the historic loss rate calculated on the basis of data on the payment of trade receivables in the period of 4 years corrected, in use, for future information. The rate calculated this way is referred to balances of unpaid trade receivables recognised as at the balance sheet date, within ranges defined in the ageing analysis.

3.19.3. Hedge accounting

The Company companies do not use hedge accounting.

4. Significant accounting judgements and estimates

When applying the accounting policies adopted by the Company, the Management Board is obliged to make estimates, judgments and assumptions regarding measurement of individual assets and liabilities. Estimates and the related assumptions are based on past experience and other factors which are considered to be material. The actual figures may be different from the adopted estimates.

The estimates and the underlying assumptions are subject to ongoing review. Changes in estimates are recognized in the period of review if they apply to that period only, or in the current and future periods if the changes apply equally to such periods.

4.1. Professional judgment in accounting

The key judgments other than those related to estimates (see Note 4.2) made by the Management Board in the process of application of the entity's accounting policies, having the most significant effect on the amounts recognized in the financial statements, are presented below.

Recognition of grants

In connection with the subsidies received, the Company is obliged to fulfill the conditions arising from the subsidy agreements signed (including result and product indicators). In the opinion of the Parent's Management Board, the potential risk of return is low.

In addition, if the Company fails to use the granted funds within the period specified in the contractual terms, they are refundable and remain for use in subsequent periods.

Recognition of patents

The Company capitalizes the costs of patents that serve to protect the rights used in the course of research (not generating revenues), as well as those that generate revenues from research and development cooperation agreements. During the periodic review of the project portfolio, the Management Board makes a significant judgment related to the possibility of generating economic benefits by certain patents in the future.

Leasing - the Company as a lessee

The Company applied the following judgments and estimates:

Lease period for contracts with extension options

The Company determines the lease term as an irrevocable lease period, including periods covered by the option to extend the lease, if it can be assumed with sufficient certainty that the option will be exercised, and periods covered by the option to terminate the lease, if it can be assumed with sufficient certainty that the option will not be exercised.

The Company has the option, under some lease contracts, to extend the duration of the asset lease. The Company applies a judgment when assessing whether there is sufficient certainty about using the extension option. This means that it takes into account all relevant facts and circumstances that constitute an economic incentive to extend it or an economic penalty for not extending it. After the commencement date, the Company reassess the lease period if there is a significant event or change in circumstances under its control and affects its ability to exercise (or not exercise) the extension option (e.g. change of business strategy).

The Company has included the extension period as part of the leasing period for the leasing of business premises and parking spaces due to the importance of these assets for operations.

Lease period for contracts of unlimited duration

The Company has lease contracts concluded for an indefinite period and contracts that have evolved into indefinite contracts in the situations provided for in the Civil Code, in which both parties have the option to terminate. When determining the leasing period, the Company determines the period of contract enforceability. Leasing ceases to be enforceable when both the lessee and the lessor have the right to terminate the contract without having to obtain permission from the other party without incurring more than insignificant penalties. The Company assesses the significance of broadly understood penalties, i.e. apart from strictly contractual or financial matters, it takes into account all other significant economic factors discouraging the termination of the contract (e.g. significant investments in leasing, availability of alternative solutions, relocation costs). If neither the Company as the lessee nor the lessor incurs a significant penalty for termination (broadly understood), leasing ceases to be enforceable and its period constitutes the notice period. However, in a situation where either party - in accordance with professional judgment - incurs a significant penalty for termination (broadly understood), the Company determines the leasing period as sufficiently reliable (i.e. the period for which it can be assumed with sufficient certainty that the contract will last).

Lessee's marginal interest rate

The Company is not able to easily determine the interest rate for leasing contracts, which is why it uses the lessee's marginal interest rate when measuring the leasing liability. This is the interest rate that the Company would have to pay to borrow for a similar period, in the same currency and with similar collateral, the funds necessary to purchase an asset with a similar value as the asset due to the right to use in a similar economic environment.

4.2. Uncertainty of estimates

Presented below are the main assumptions concerning the future and other uncertainties as at the end of the reporting period, which pose a considerable risk of material adjustments to the carrying amounts of assets and liabilities in the following financial year.

4.2.1. Provisions for bonuses

Provisions for bonuses are presented in Note 31. Provisions for bonuses are estimated in line with an algorithm based on a margin achieved and realized on individual projects or project Companys. The Management Board estimates the value of bonuses to be paid on the basis of the results of the aforesaid calculations. The Management Board considers numerous factors, such as the current and anticipated economic and financial position of the Company. Bonuses are discretionary.

4.2.2. Useful lives of property, plant and equipment

As described in Note 3.13 and in Note 3.14, the Company reviews the estimated useful lives of items of property, plant and equipment and intangible assets at the end of each annual reporting period. In the current financial year, the Management Board did not identify the necessity to reduce the value in use of any assets.

4.2.3. Accounting for long-term contracts using the estimated stage-of-completion method

As described in Note 3.6, the Company determines the stage of completion of contracts with clients by determining the proportion of the project costs incurred so far to the total estimated project costs. Due to the nature of the projects being carried out, as well as the possibility of the occurrence of previously unforeseen difficulties associated with the implementation of the project, it may turn out that the actual total costs of project implementation will differ from the estimates made. A change in the estimated total costs of project implementation may cause that the project progress level as at the balance sheet date, and thus the recognized revenue, should be set at a different value. Project costs are updated on an ongoing basis by the Project Manager, which reduces the risk of large deviations of actual costs from the forecast.

4.2.4. Deferred tax asset

The Company recognizes a deferred tax asset based on the assumption that a tax profit will be available in the future to allow its use. Deterioration of tax results in the future could cause that this assumption would become unjustified.

The Company carefully assesses the nature and extent of evidence justifying the conclusion that it is probable that future taxable income will be sufficient to deduct the unused tax losses, unused tax credits or other negative temporary differences.

When assessing whether it is probable that future taxable profit will be achieved (probability above 50%), the Company shall take into account all available evidence, both confirming the existence of probability and evidence of its absence.

Based on the forecasts for the following years, the Management Board of the Company makes a decision on calculating the deferred tax asset.

4.2.5. Tax settlements

Regulations regarding value added tax, corporate income tax and social security charges are subject to frequent changes. These frequent changes result in a lack of well-established benchmarks, inconsistent interpretations, and few precedents established that could apply. There are no explicit interventions clearly defining tax regulations and relations between both state authorities as well as state authorities and enterprises.

Tax settlements and other areas of activity may be subject to control by authorities that are entitled to impose penalties and fines, and any additional tax obligations resulting from the control must be paid together with interest. These conditions cause increased tax risk.

Consequently, the amounts presented and disclosed in the financial statements may change in the future as a result of the final decision of the tax inspection authority.

On July 15, 2016, the Tax Code was amended to take into account the provisions of the General Fraud Prevention Clause (GAAR). GAAR is to prevent the emergence and use of artificial legal structures created to avoid payment of tax in Poland. GAAR defines tax avoidance as an act performed primarily to achieve a tax benefit, which is in conflict with the subject and purpose of the provisions of the Tax Act. According to GAAR, this does not result in a tax benefit if the method of operation was artificial. Any occurrence of (i) unjustified division of operations, (ii) the involvement of intermediaries despite the lack of economic or economic justification, (iii) elements that mutually abolish or compensate each other, and (iv) other activities similar to those mentioned above, may be treated as a premise for existence artificial activities subject to GAAR. The new regulations will require much more judgment when assessing the tax consequences of individual transactions.

The GAAR clause should be applied to transactions made after its entry into force and to transactions that were carried out before the GAAR clause entered into force, but for which benefits were or are still being achieved after the date of entry into force of the clause. The implementation of the above provisions will enable Polish tax inspection authorities to question the legal arrangements and agreements implemented by taxpayers, such as the restructuring and reorganization of the Company.

The Company recognizes and measures current or deferred tax assets or liabilities using the requirements of IAS 12 Income tax based on profit (tax loss), tax base, unused tax losses, unused tax credits and tax rates, taking into account the uncertainty associated with settlements tax.

If, in the opinion of the Company, it is likely that the Company's approach to the tax issue or Company of tax issues will be accepted by the tax authority, the Company determines taxable income (tax loss), tax base, unused tax losses, unused tax credits and tax rates taking into account the approach to taxation planned or applied in your tax return. Assessing this probability, the Company assumes that the tax authorities authorized to audit and challenge the tax treatment will carry out such control and will have access to all information.

If the Company determines that it is not probable that the tax authority will accept the Company's approach to the tax issue or Company of tax issues, then the Company reflects the effects of uncertainty in accounting terms of tax during the period in which it determined it. The Company recognizes an income tax liability using one of the following two methods, depending on which of them better reflects the way in which uncertainty can materialize: · The Company determines the most likely scenario - this is a single amount among the possible outcomes or

· The Company recognizes the expected value - it is the sum of probability weighted amounts among the possible results.

4.2.6. Fair value of financial instruments

The fair value of financial instruments for which there is no active market is determined using appropriate valuation techniques. When selecting the appropriate methods and assumptions, the Company is guided by professional judgment. The method of determining the fair value of individual financial instruments is presented in Note 18.

4.2.7. Impairment of trade receivables and contract assets

The company uses reserve matrices to value the write-down for expected credit losses in relation to trade receivables and assets under the contract. In order to determine the expected loan losses, trade receivables and contract assets were Companyed based on the similarity of the credit risk characteristics. The company uses its historical data on credit losses, adjusted, where appropriate, by the impact of future information. An increase or decrease in the adjustment regarding the impact of future factors used to estimate the expected loan losses by 10% would result in an increase or decrease in write-offs for credit losses by PLN 2,720, respectively.

4.2.8. Revenue recognition

Judgments made by the Company that significantly affect the determination of the amount and timing of obtaining revenues from contracts with clients are presented in Note 3.6.

5. Sales revenue

5.1. Revenues

The sales revenues obtained by the Company can be divided into 3 types. The main type of contracts is the sale of R&D projects, while the "fixed price" and FTE contracts were implemented by a separate service segment and are being terminated.

1. Agreements based on the fixed price model.

In the "fixed price" model under the concluded contract, the Company provides specific services for a specific amount of remuneration. In such cases, invoicing usually takes place in the following pattern: a certain percentage of the advance (the so-called upfront payment) and the remainder at the time of the contract.

In accordance with the Company's policy, some of this type of contracts were measured in accordance with the cost-advanced method as long-term contracts. These types of contracts is considered individually in the context of the moment of fulfilling the obligation to perform the service and thus the impact on the moment of recognition of revenues.

2. Agreements based on the FTE (Full-Time Equivalent) model

Under the contract, the Company provides appropriately qualified employees. Revenue is defined as the working time of employees of the Company measured at the rate from the contract. Invoices in accordance with the contract are issued at the end of the set settlement period (usually monthly). The Company's obligation to perform the service is therefore met at the time the employees render the service.

3. Sale of R&D projects

The company concludes research and development cooperation agreements. The subject of cooperation is the discovery and development of innovative small molecule compounds with potential therapeutic use in inflammatory diseases. The cooperation agreement specifies the division and scope of responsibility between the Company and the partner. At the time of signing the contract, the Company receives payment in advance, which is a remuneration for access to the existing test results. Other revenues depend on the achievement of specific scientific and clinical research progress, the success of the registration process, the so-called 'milestones', and the level of revenue from the sale of a potential drug achieved by the partner. The Company receives contractual remuneration for the defined 'milestone' achieved. In addition, the Company is guaranteed royalties on the sale of products developed as a result of cooperation.

The Company does not have sufficient information and has no influence on the pace of work performed by the project partner to be able to precisely determine when the conditions resulting in payments to the Company within the agreed, defined 'milestones' will be fulfilled, therefore the recognized revenue relates only to these revenues for which the milestone has been reached. Then the recognized revenue corresponds to the remuneration for the achieved milestone.

The breakdown of the Company's sales revenues for continuing operations is as follows:

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Contract research - fixed priced agreements	25,998	360,205
Lease of employees - FTE agreements	1,072,960	3,438,126
Sale of R&D projects	14,315,350	-
Rent revenue	236,216	-
Operating income	15,650,524	3,798,331

The above analysis does not reflect the Company's operating segments, which are described in note 6.

5.2. Revenues from subsidies

	Year ended 31/12/2020	Year ended 31/12/2019
Infrastructure subsidies	2,717,375	2,125,927
Grants for research	18,582,784	27,796,009
	21,300,159	29,921,936

5.3. Contract assets and liabilities

The scope of changes of contract assets	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN
Contracts at the beginning of the reporting period	360,205	596,421	235,994
Revenue accrued in proportion to the costs incurred	-	607,966	1,965,074
Invoiced revenues	(360,205)	(844,182)	(1,604,647)
Contracts assets at the end of the reporting period	-	360,205	596,421

The scope of changes of contract liabilities

Revenue accrued in proportion to the costs incurred Invoiced revenues Contracts at the beginning of the reporting period

Contracts liabilities at the end of the reporting period

Balance as at 01/01/2019	Balance as at 31/12/2019	Balance as at 31/12/2020
PLN	PLN	PLN

206,180	759,510	-
(770,874)	(759,510)	-
1,324,204	-	-
759,510	-	-

5.4. Geographical information

The Company operates in two major geographical regions – in Poland, where its registered office is located, and in Europe.

Company's revenue from external customers by geographical area:

	Revenue from external customers
Year ended 31/12/2020	Year ended 31/12/2019
PLN	PLN
272,486	1,300
15,378,038	3,780,252
-	16,779
15,650,524	3,798,331

5.5. Operating expenses

	Year ended 31/12/2020	Year ended 31/12/2019
5.5.1. Amortization and impairment	PLN	PLN
Depreciation of tangible asstes	7,543,637	4,273,702
Depreciation of the rights to use machines and equipment	1,517,054	1,718,169
Depreciation of rights to use of buildings	1,208,399	1,679,868
Depreciation of rights to use of cars	99,199	99,199
Amortization of intangible assets and liquidation of patents	1,988,834	217,697
Total amortization expense	12,357,123	7,988,635

5.5.2. Employee benefit expense	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Salaries and wages	21,930,468	24,508,790
Social security charges	2,986,333	3,371,672
Medical and other benefits	710,929	329,461
Trainings	221,889	160,980
Workwear	162,349	29,167
Employee benefit expense	26,011,968	28,400,070

5.5.3. External services	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
B2C Services*	4,007,685	10,805,972
Administrative services	5,468,745	1,410,000
IT services, databases	1,343,502	1,039,019
Research Services	13,015,633	13,330,496
Transportation services	331,946	512,049
Total external services	24,167,511	27,097,536

* B2C costs include costs of outsourcing human resources and costs of subcontractors used in research projects in the amount of PLN 562.9 thousand in the period ended December 31, 2020 and PLN 85 thousand in the whole year 2019.

6. Operating segments

Currently, we deal with one operating and reporting segment and the Management Board monitors both the operating results and financing of the Company and income tax at the level of the entire Company in order to make decisions regarding the allocation of resources, assess the effects of this allocation and the results of operations.

6.1. Products and services representing a source of revenue of the reporting segments

Currently, the only operating segment is Innovation (continuing operations). The company conducts research and development works in which it focuses on developing innovative, small-molecule pharmacological compounds that are intended for commercialization at a later stage of the development of new drugs.

Before the split, the Company also had a Services segment in which it provided services through two main departments: Contract Chemistry Department and Contract Biology Department. Upon the completion of the division process, the Company ceased operations in this segment.

6.2. Segment revenue and profit or loss

Analysis of the Company's reporting segment revenue and profit or loss:

a) Continued operations

	Revenue		Operating profit
	Year ended	Year ended	Year ended	Year ended
	31/12/2020	31/12/2019	31/12/2020	31/12/2019
	PLN	PLN	PLN	PLN
Segment 1 - Innovations, including	37,327,566	34,138,733	(35,697,025)	(45,385,247)
revenue from external customers	15,650,524	3,798,331
grant income	21,300,159	29,921,936
other operating income	376,883	418,466
Total from continued operations	37,327,566	34,138,733	(35,697,025)	(45,385,247)

	Expenses
	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Segment 1 - Innovations, including	73,024,591	79,523,980
amortization and depreciation	12,357,123	7,988,635

6.3. Segment assets and liabilities

a) Continued operations

	Balance as at	Balance as at
	31/12/2020	31/12/2019
	PLN	PLN
Segments assets
Segment I
Innovations	295,640,268	183,629,803
Total segment assets	295,640,268	183,629,803
Segment liabilities
Segment I
Innovations	71,919,509	63,049,627
Total segment liabilities	71,919,509	63,049,627
b) Discontinued operations
	Balance as at	Balance as at
	31/12/2020	31/12/2019
	PLN	PLN
Segments assets
Segment II
Services	-	-
Total segment assets	-	-
Segment liabilities
Segment II
Services	-	-
Total segment liabilities	-	-

For purposes of monitoring segment performance and allocating resources:

● reporting segments include: goodwill, unfinished development, shares in associates, long-term receivables, cash and cash equivalents, property, plant and equipment, inventories, trade receivables, subsidies, assets under long-term contracts, deferred tax asset,

● unallocated assets include: unallocated tangible assets, other intangible assets, public-law and employee receivables, other assets.

● reporting segments include trade payables, trade payables, provisions for liabilities, deferred income, financial liabilities

6.4. Other segment information

			Year ended
31/12/2020	31/12/2019	31/12/2020	31/12/2019
PLN	PLN	PLN	PLN

12,357,123	7,988,635	36,976,111	37,612,646
12,357,123			37,612,646
	Year ended	Depreciation and amortization Year ended	Fixed assets additions Year ended 7,988,635 36,976,111

6.5. Major customers

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Segment 1 - Innovations
Customer A	8,603,086	1,295,150
Customer B	6,791,400	-
Customer C	-	1,998,849

Customers A,B, C are customers for which the sales revenue exceeds 10% of segment sales revenue.

7. Finance income

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Financial revenue due to financial instruments	218,850	906,591
Interest received	218,850	906,591
Total finance income	218,850	906,591

8. Finance cost

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Finance cost due to financial instruments	246,088	513,286
Interest	132,163	352,483
Gains / losses on fx differences	113,925	160,803
Other finance cost	255,269	45,832
Interest on leases	255,269	45,832
Total finance cost	501,357	559,118

9. Other operating income and expenses

9.1. Other operating income

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Gain on disposal of property, plant and equipment	-	-
Other operating income:	376,883	418,466
Written off liabilities	7,855	101,164
Other - sales of services to employees (benefits)	313,412	317,094
Other - cancellation of leasing contracts	55,616	208
Total other operating income	376,883	418,466

9.2. Other operating expenses

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Loss on disposal of property, plant and equipment	-	-
Revaluation of non-financial assets	-	-
Other operating expenses:	47,041	82,140
Cost refund to employees – prescription glasses	1,200	3,200
Donations	20,000	74,034
Other	25,841	4,906
Total other operating expenses	47,041	82,140

10. Income taxes on continuing operations

10.1. Income taxes presented in the statement of comprehensive income

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Current income tax:	-	-
Current income tax expense	-	-
Corrections relating to previous years	-	-
Deferred income tax	(1,072,029)	(160,890)
Tax charge presented in the statement of comprehensive income	(1,072,029)	(160,890)

10.2. Reconciliation of the tax profit to the accounting profit

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Recorded revenue and profit	42,910,390	35,973,704
Revenue and profits of spin-off operations	-	50,612,894
Non-taxable and tax-exempt income, including:	27,856,217	34,354,326
Fx differences	1,522,035	1,330,524
Long-term contracts	(356,620)	1,774,401
Grant income	21,326,829	31,187,013
Other - valuation of shares in Nodthera	5,363,973	928,380
SEZ revenue	-	(865,992)
Tax revenues, other than accounting revenues:	-	-
Long-term contracts	-	-
Total taxable income (1-2+3)	15,054,172	52,232,272
Recorded expenses and losses	73,525,948	80,083,098
Expenses and losses of spin-off operations	-	41,680,052
Expenses and losses classified permanently as non-deductible:	21,588,222	30,228,032
PFRON	181,271	285,642
Business entertainment costs	28,036	278,299
Subsidized costs	21,326,829	31,187,013
Other non-deductible expenses	52,086	93,215
SEZ costs	-	(1,616,137)
Expenses and losses classified temporarily as non-deductible:	7,266,939	4,882,702
Recognized accruals for bonus and unused holiday	2,260,635	894,812
Recognized other accruals	3,218,067	2,733,501
Exchange differences	1,777,115	1,252,017
Outstanding salaries, wages and social security	2,177	-
Other non-deductible expenses	8,945	2,372
Tax costs, other than accounting costs:	-	-
Total deductible expenses	44,670,787	86,652,416
Taxable Income / (Loss)	(29,616,615)	(34,420,144)
Tax-exempt income ("+")	-	-
Deductions from income ("+")	-	-
Podstawa opodatkowania Income tax at the applicable rate	(29,616,615) -	(34,420,144) -
Deductions from income tax
Income tax due	-	-

The tax charge is determined using the tax rates effective in the financial year. Since 2004, under the amended legislation, the CIT rate has been 19%.

10.3. The effective tax rate reconciliation is as follows:

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Gross (Loss) before tax from continued operations Gross (Loss) before tax from discontinued operations	(30,615,558) -	(44,109,394) 611,914
Gross (Loss) before tax	(30,615,558)	(43,497,480)

Tax at the statutory tax rate applicable in Poland, 19% Permanent non-taxable costs	(5,816,956) 4,101,762	(8,264,521) 5,743,326
Permanent non-taxable income	(4,052,098)	(5,925,532)
Others (e.g.: unrecognized deferred tax asset)	4,695,262	8,285,837
Tax at the effective tax rate	(1,072,029)	(160,890)
10.4. Current tax asset and liabilities
	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Current tax asset
Tax refund due	-	-
	-	-
Current tax liabilities

- -

Income taxes due - -

10.5. Deferred income tax

Analysis of the deferred tax asset / (liability) in the statement of financial position:

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Deferred tax asset	593,525	700,790	-
Deferred tax liability	6,042,042	5,143,717	4,430,225
	(5,448,517)	(4,442,927)	(4,430,225)

Basis for temporary differences – difference between the tax value and carrying amount of:		DTA as at		Change in DTA recognized in profit and loss account for the period		Change in DTA recognized in equity
	Balance as at	Balance as at	Balance as at	From 01/01 to	From 01/01 to	From 01/01 to	From 01/01 to
	31/12/2020	31/12/2019	01/01/2019	31/12/2020	31/12/2019	31/12/2020	31/12/2019
- fixed assets and intangible assets (excluding leases)	-	7,828	-	(7,828)	7,828	-	-
- fixed assets and intangible assets - leases	269,426	342,535	-	(73,109)	342,535	-	-
- contract with clients	-	-	-	-	-	-	-
- personnel related accruals	-	112,545	-	(112,545)	112,545	-	-
- other provisions	-	-	-	-	-	-	-
- trade and other receivables and payables (negative foreign exchange)	324,099	237,882	-	86,217	237,882	-	-
Total	593,525	700,790	-	(107,265)	700,790	-	-

10.6. Unrecognized deferred tax asset and unused tax credits

	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
Recognized tax assets	593,525	700,790	-
As at the end of the reporting period, the following items of the deferred tax asset
remained unrecognized: Tax losses	9,497,137	3,869,980	405,495
Other accruals	332,027	530,409	-
Accruals for bonuses and unused holidays	882,214	452,693	115,370
FX differences	13,553	-	-
Total unrecognized deferred tax asset	10,724,931	4,853,082	520,865
Total (recognized and unrecognized) deferred tax asset	11,318,455	5,553,872	520,865

DTA computation method has been described in note 4.2.4.

Unrecognized assets due to unused tax losses concern the years 2016, 2019 and 2020 and may be settled by 2025.

10.7. Deferred tax liability

Basis for temporary differences – difference between the tax value and carrying amount of:		DTL		Change in DTL recognized in profit and loss account for the period	Change in DTL recognized in equity
	Balance as at	Balance as at	Balance as at	From 01/01 to	From 01/01 to	From 01/01 to	From 01/01 to
	31/12/2020	31/12/2019	01/01/2019	31/12/2020	31/12/2019	31/12/2020	31/12/2019
- fixed assets and intangible assets (excluding leases)	-	195,098	51,211	-	143,887	-	-
- fixed assets and intangible assets - leases	322,301	216,663	83,251	105,638	133,412	-	-
- trade and other receivables (exchange differences) - receivables (revenues accrued statistically) interest on	289,187	252,799	10,897	36,388	241,902	-	-
deposits	-	-	29,989	-	(29,989)	-	-
- contracts with clients - trade receivables and liabilities and others (positive exchange	27,084	94,842	46,954	(67,758)	47,888	-	-
differences)	-	-	-	-	-	-	-
- revaluation of shares in Nodthera	5,403,470	4,384,315	4,207,923	1,019,155	176,392	-	-
Total	6,042,042	5,143,717	4,430,225	1,093,423	713,492	-	-

11. Non-current assets held for sale

None.

12. Earnings per share

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN/100 per share	PLN/100 per share
Basic earnings per share:	(189.0)	1,788.5
From continuing operations	(189.0)	(277.2)
From spin-off operations	n.a.	2,065.7
Total basic earnings per share	(189.0)	1,788.5
Diluted earnings per share:	(189.0)	1,788.5
From continuing operations	(189.0)	(277.2)
From spin-off operations	n.a.	2,065.7
Total diluted earnings per share	(189.0)	1,788.5

12.1. Basic earnings per share

Earnings and weighted average number of ordinary shares used for calculation of basic earnings per share:

	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Profit used to calculate the total basic earnings per share	(31,687,588)	285,640,010
Profit used to calculate basic earnings per share from spin-off operations	-	329,910,294
Profit used to calculate basic earnings per share from continuing operations	(31,687,588)	(44,270,284)

	Year ended 31/12/2020	Year ended 31/12/2019
	quantity	quantity
Weighted average number of ordinary shares used to calculate diluted earnings per share	16,765,977	15,971,229

13. Tangible fixed assets

	Balance as at	Balance as at	Balance as at
Net carrying amount:	31/12/2020	31/12/2019*	01/01/2019*
	PLN	PLN	PLN

Land	7,468,450	7,468,450	7,468,450
Buildings	46,198,885	708,033	1,866,213
Machinery and equipment	10,982,466	226,911	476,420
Vehicles	-	-	-
Other tangible assets (including lab equipment)	17,443,008	14,938,919	20,594,751
Rights to use other fixed assets (including laboratory equipment)	2,924,748	4,203,527	4,227,616
Rights to use the premises	1,377,601	1,424,512	16,955,936
Rights to use cars	182,593	281,789	643,687
Assets under construction	4,584,560	36,937,340	6,872,335
Advances for assets under construction	-	-	-
	91,162,311	66,189,481	59,105,408

* data as at January 1 and December 31, 2019 have been restated (see Note 13.2)

In the periods covered by the financial statements, the Company did not make revaluation write-offs for fixed assets.

The company reviewed the premises for impairment of property, plant and equipment. Given that the most important items are new or almost new assets or relate to fixed assets under construction (newly built Innovative Medicines Research and Development Center), the Company's Management Board decided that the fair value of these assets less selling costs is equal to or greater than the book value of the assets. Moreover, the Management Board took into account the level of the company's capitalization as at 31/12/2020 and as at the date of approval of these financial statements and due to the surplus of capitalization over the company's net assets at the level of approximately PLN 677m, the Management Board concluded that there are no indications of impairment. and therefore the Management Board does not see the need to recognize an impairment loss as at 31/12/2020.

In 2021, the Company plans expenditures on non-financial fixed assets in the amount of PLN 19,300 thousand which are related to the completion of equipping the newly built Research and Development Center of Innovative

Liabilities secured on the entity's assets

	As at 31/12/2020		As at 31/12/2019		As at 01/01/2019
Type of security	Value of liability	Value of security	Value of liability	Value of security	Value of liability	Value of security	Nature and form of security
Mortgage	2,362,057.00	8,403,000.00	3,171,878.00	8,403,000.00	3,981,698.00	8,403,000.00	The property located in Krakow at ul. Sternbach, consisting of registration plots located within 38 with numbers: 81/21, 81/26, 195/11, 195/16, 210/24, 210/9, 210/8, 210/19, 210/3, 210/2
Pledges, incl.:	3,330,094.00	3,330,094.00	4,626,818.00	4,626,818.00	4,079,134.00	4,079,134.00
machinery - leasing	3,330,094.00	3,330,094.00	4,626,818.00	4,626,818.00	4,079,134.00	4,079,134.00	laboratory equipment
Promissory note, incl.:	2,362,057.00	2,362,057.00	3,171,878.00	3,370,552.00	3,981,698.00	4,294,322.00
Promissory note	2,362,057.00	2,362,057.00	3,171,878.00	3,370,552.00	3,981,698.00	4,294,322.00	cash on bank accounts
Contractual right to set off the claim against the account holder's
claim	2,362,057.00	2,362,057.00	3,171,878.00	3,370,552.00	3,981,698.00	4,294,322.00	cash on bank accounts
TOTAL	10,416,265.00	16,457,208.00	14,142,452.00	19,770,922.00	16,024,228.00	21,070,778.00

13.1. Changes in the value of fixed assets by type

Item	Land	Buildings	Machinery and equipment	Vehicles	Other tangible assets (including lab equipment)	Assets under construction	Rights to use other fixed assets (including laboratory equipment)	Rights to use the premises	Rights to use cars	Total
Gross value as at 01.01.2020 after adjustment	7,468,450	1,889,677	1,939,317	-	29,490,785	36,937,340	8,791,485	3,104,380	380,988	90,002,422
Increases in gross value:	-	46,438,722	11,169,776	-	8,680,403	34,179,581	243,461	1,161,538	-	101,873,481
- Purchases	-	-	-	-		34,179,581	-	-	-	34,179,581
- Transfer from assets under construction	-	46,438,722	11,169,776	-	8,680,403	-	243,461	-	-	66,532,362
- Other	-	-	-	-	-	-	-	1,161,538	-	1,161,538
Decreases in gross value:	-	-	-	-	-	66,532,362	-	-	-	66,532,362
- Other, transfer from assets under construction	-	-	-	-	-	66,532,362	-	-	-	66,532,362
Gross value as at 31.12.2020	7,468,450	48,328,399	13,109,093	-	38,171,188	4,584,559	9,034,946	4,265,918		380,988 125,343,541
Accumulated depreciation as at 01.01.2020 after adjustment	-	1,181,644	1,712,406	-	14,551,866	-	4,587,958	1,679,868	99,199	23,812,941
Inceases in accumulated depreciation:	-	947,870	414,221	-	6,181,546	-	1,517,054	1,208,399	99,199	10,368,289
- Depreciation charge for the period	-	947,870	414,221	-	6,181,546	-	1,517,054	1,208,399	99,199	10,368,289
Decreases in accumulated depreciation:	-	-	-	-	-	-	-	-	-	-
- Liquidation	-	-	-	-	-	-	-	-	-	-
Accumulated depreciation as at 31.12.2020	-	2,129,514	2,126,627	-	20,733,412	-	6,105,012	2,888,267	198,398	34,181,230
Net carrying amount as at 01.01.2020 after adjustment	7,468,450	708,033	226,911	-	14,938,919	36,937,340	4,203,527	1,424,512	281,789	66,189,481
Net carrying amount as at 31.12.2020	7,468,450	46,198,885	10,982,466	-	17,437,776	4,584,559	2,929,934	1,377,651	182,590	91,162,311

In 2020, the Company completed the construction of the Research and Development Center for Innovative Medicines. The heart of the new facility of the Company is a complex of laboratories in the field of, among others, medical chemistry, biochemistry, molecular and cell biology and analytics, reflecting the course of the research on innovative drugs. increase the scale of projects implemented by the Company The building consists of 6 floors with a total area of approximately 10,000 square meters, including over 8,000 square meters of usable space for both laboratories and offices:

laboratory area: approx. 3 thousand square meters,
office space: approx. 1 thousand square meters (including offices and conference rooms),
technical and social rooms: approx. 1.3 thousand square meters,
others: parking, communication: approx. 2,900 square meters.

The facility was put into operation in June 2020 and consists of the following components:

Nazwa	Value
The building at ul. Strenbacha 2 in Krakow	42,776,357
Installation of ventilation and air conditioning	10,362,927
Sprinkler installations	1,283,453
Installation of technical gases	1,243,000
Access roads and greenery	1,135,911
Total	56,801,648

For each of the separated components, the economic useful life was individually estimated.

13.2. Changes in the value of fixed assets by type from 01.01.2019 to 31.12.2019

Item	Land	Buildings	Machinery and equipment	Vehicles	Other tangible assets (including lab equipment)	Assets under construction	Rights to use other fixed assets (including laboratory equipment)	Rights to use the premises	Rights to use cars	Total
Gross value as at 01.01.2019	7,468,450	3,044,915	2,865,612	102,050	37,144,997	6,872,375	8,567,352	13,357,622	262,699	79,686,072
Adjustment	-	-	-	-	3,771,860	-	-	3,598,314	380,988	7,751,162
Gross value as at 01.01.2019 after adjustment	7,468,450	3,044,915	2,865,612	102,050	40,916,857	6,872,375	8,567,352	16,955,936	643,687	87,437,234
Increases in gross value after adjustment:	-	41,690	424,371	-	814,269	39,146,304	3,247,738	-	-	43,674,372
- Purchases after adjustment	-	41,690	424,371	-	814,269	39,146,304	3,247,738	-	-	43,674,372
Decreases in gross value after adjustment:	-	1,196,928	1,350,666	102,050	12,240,341	9,081,339	3,023,605	13,851,556	262,699	41,109,184
- Disposal	-	-	-	-	406,410	48,714	-	-	-	455,124
- Liquidation - change of leasing agreements, adjustment	-	-	-	-	-	-	368,794	13,851,556	262,699	14,483,049
- Other, transfer from assets under construction	-	-	-	-	-	8,585,068	-	-	-	8,585,068
- Spin-off of OPE	-	1,196,928	1,350,666	102,050	11,833,931	447,557	2,654,811	-	-	17,585,943
Gross value as at 31.12.2019 after adjustment	7,468,450	1,889,677	1,939,317	-	29,490,785	36,937,340	8,791,485	3,104,380	380,988	90,002,422
Accumulated depreciation 01.01.2019	-	1,178,702	2,389,192	102,050	16,550,246	-	4,339,736	-	-	24,559,926
Adjustment	-	-	-	-	3,771,860	-	-	-	-	3,771,860
Accumulated depreciation 01.01.2019 after adjustment	-	1,178,702	2,389,192	102,050	20,322,106	-	4,339,736	-	-	28,331,786
Inceases in accumulated depreciation:	-	277,237	580,900	-	3,415,565	-	1,718,169	1,679,868	99,199	7,770,938
- Depreciation charge for the period	-	277,237	580,900	-	3,415,565	-	1,718,169	1,679,868	99,199	7,770,938
Decreases in accumulated depreciation:	-	274,295	1,257,686	102,050	9,185,805	-	1,469,947	-	-	12,289,783
- Disposal	-	-	-	-	406,410	-	-	-	-	406,410
- Liquidation	-	-	-	-	27,842	-	-	-	-	27,842
- Spin-off of OPE	-	274,295	1,257,686	102,050	8,751,553	-	1,469,947	-	-	11,855,531
Accumulated depreciation as at 31.12.2019 after adjustment	-	1,181,644	1,712,406	-	14,551,866	-	4,587,958	1,679,868	99,199	23,812,941
Net carrying amount as at 01.01.2019 after adjustment	7,468,450	1,866,213	476,420	-	20,594,751	6,872,375	4,227,616	16,955,936	643,687	59,105,448
Net carrying amount as at 31.12.2019 after adjustment	7,468,450	708,033	226,911	-	14,938,919	36,937,340	4,203,527	1,424,512	281,789	66,189,481

The Company made a presentation adjustment as at January 1, 2019 due to a PLN 4 million reduction in assets and liabilities related to the right to use of premises related to the Selvita S.A. Group before the separation of OPE and reorganization.

The Company made a presentation adjustment as at December 31, 2019 due to the overvaluation of assets due to the right to use of other fixed assets by PLN 4.3 million, which amount was partially incorrectly presented as own other fixed assets. At the same time, the liabilities due to the right of use presented as at December 31, 2019 were overstated by PLN 4.3 million. The presentation correction affects Note 13.2, Note 13 and Note 23.

14. Intangible assets

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
Carrying amount	PLN	PLN	PLN
Patents*	2,217,715	2,848,680	2,232,980
Software	-	-	-
Other intangible assets	100,819	74,974	150,684
	2,318,534	2,923,654	2,383,664

* Patents protect rights that are currently at the research level and do not generate revenue, but also those that generate revenue from partnering agreements.

The Company does not use any intangible assets under lease agreements.

14.1. Changes in the value of intangible assets by type in the current reporting period

Item	Other intangible assets	Total
Gross value as at 01.01.2020 after adjustment	4,038,550	4,038,550
Increases in gross value:	1,391,531	1,391,531
- Purchases	1,391,531	1,391,531
Decreases in gross value:	1,859,632	1,859,632
- other	7,817	7,817
- liquidation	1,851,815	1,851,815
Gross value as at 31.12.2020	3,570,449	3,570,449
Accumulated depreciation as at 01.01.2020 after adjustment	1,114,896	1,114,896
Inceases in accumulated depreciation:	277,956	277,956
- Depreciation charge for the period	277,956	277,956
Decreases in accumulated depreciation:	140,937	140,937
- liquidation	140,937	140,937
Accumulated depreciation as at 31.12.2020	1,251,915	1,251,915
Net carrying amount as at 01.01.2020 after adjustment	2,923,654	2,923,654
Net carrying amount as at 31.12.2020	2,318,534	2,318,534

The Company decided to liquidate the patents in connection with abandonment of work on related projects.

14.2 Changes in the value of intangible assets by type in period from 01.01.2019 to 31.12.2019

Item	Other intangible assets	Total
Gross value as at 01.01.2019	3,426,203	3,426,203
Increases in gross value after adjustment:	858,112	858,112
- Purchases	858,112	858,112
Decreases in gross value after adjustment:	245,765	245,765
- Spin-off of OPE	245,765	245,765
Gross value as at 31.12.2019 after adjustment	4,038,550	4,038,550
Accumulated depreciation 01.01.2019	1,042,539	1,042,539
Inceases in accumulated depreciation:	264,405	264,405
- Depreciation charge for the period	264,405	264,405
Decreases in accumulated depreciation:	192,048	192,048
- Spin-off of OPE	192,048	192,048
Accumulated depreciation as at 31.12.2019 after adjustment	1,114,896	1,114,896
Net carrying amount as at 01.01.2019 after adjustment	2,383,664	2,383,664
Net carrying amount as at 31.12.2019 after adjustment	2,923,654	2,923,654

15. Subsidiaries

The company has no subsidiaries as at December 31, 2020, as well as December 31, 2019. As at January 1, 2019, the Company held shares in BioCentrum sp. z o.o., Selvita Services sp. z o.o., Ardigen SA, Selvita Ltd, Selvita Inc. On October 1, 2019, the shares in these subsidiaries were, as a result of the split, transferred to Selvita S.A.

16. Split of the Company

On 19.09.2019, the Extraordinary General Meeting of Ryvu Therapeutics S.A. with its registered office in Kraków ("Divided Company"), acting pursuant to Article 541 § 1 - § 7 CCC in connection with Article 528 § 1 CCC, 529 § 1 item 4) of the CCC in connection with Article 530 § 2 CCC, Article 393 point 3) of the CCC and § 19 section 1 point o) of its Status decided to split the Divided Company and transfer to Selvita SA (formerly operating under the name Selvita CRO SA) part of the property of Ryvu Therapeutics SA, as part of which carried out service activities in the field of biotechnology consisting in the provision of laboratory research and development services ranging from computer and chemical design of molecules, through their chemical synthesis, ending with analytical work and preclinical studies commissioned by, inter alia, pharmaceutical, biotechnological and chemical companies, creating organizationally and financially separate Company of tangible and intangible assets, intended for conducting business activity, constituting an organized part of the enterprise of the Splited Company ("OPE"), in financial reports presented as Service and Bioinformatics Segment.

The split of the Company, in the light of IFRIC 17, was a transfer of non-cash assets to the Company's shareholders, i.e. a non-monetary dividend payment to shareholders included in correspondence with equity in the same amount. The application of this standard resulted in recognition in a separate item in the profit and loss account of "Gain on spin-off" in the amount of PLN 321 million in 2019, which is the difference between the fair value of all shares of Selvita CRO S.A. (currently Selvita S.A.), calculated as the product of the number of shares and the closing price from the first day of listing on the WSE, i.e. October 16, 2019, and the net asset value transferred in the form of OPE. It was a non-cash item and resulted directly from the division and receipt of 1: 1 ratio of shares in Selvita CRO S.A. (currently Selvita S.A.) by the shareholders of Ryvu Therapeutics S.A.

	Computation	Value in PLN
Fair value	21 * 15.971.229 shares=	335,395,809
Net assets of OPE		14,418,357
Gain on spin-off		320,977,452

The spin-off net assets are presented in the table below:

Non-current assets
Tangible fixed assets	4,545,548.00
Lease assets	1,184,864.00
Other Intangible assets	53,718.00
Investments in associates	6,599,616.25
Other financial assets	225,193.00
Total non-current assets	12,608,939.25
Current assets
Inventory	698,582.00
Trade and other receivables	10,513,724.56
Contract assets	1,852,003.00
Other financial assets	65,628.00
Other non-financial assets	812,695.92
Total current assets	13,942,633.48
Total assets	26,551,572.73
Long-term liabilities
Lease liabilities	750,200.72
Retirement provision	64,376.15
Total long-term liabilities	814,576.87
Short-term liabilities
Trade and other liabilities	7,845,096.62
Contract liabilities	718,309.00
Lease liabilities	375,100.00
Accrued expenses	2,380,132.91
Total short-term liabilities	11,318,638.53
Total liabilities	12,133,215.40
Net assets	14,418,357.33

The statement of comprehensive income for the period from January 1, 2019 until the separation of OPE, i.e. September 30, 2019.

	01/01/2019 - 30/09/2019
	IFRS
Spin-off operations
Sales revenue	38,768,832
Grant income	1,212,902
Other operating income	372,226
Total operating revenue	40,353,960
Amortization and depreciation	(2,885,462)
Consumption of materials and supplies	(7,811,655)
External services	(15,371,174)
Employee benefit expense	(12,707,007)
Taxes and charges	(347,999)
Other expenses	(872,676)
Other operating expenses	(53,409)
Total operating expenses	(40,049,382)
Operating profit	304,578
Financial revenue	307,336
Financial expenses	-
Profit before income tax	611,914
Income tax expense	-
Net profit on spin-off operations	611,914
Dividend on discontinued operations	8,320,928
Total income from spin-off operations	8,932,842

17. Valuation of shares in Nodthera

As at December 31, 2020, the Company held shares in NodThera Ltd.

Reconciliation of the financial data to the carrying amount of shares in NodThera Ltd. recognized in the Company's financial statements as at December 31, 2019 (after another increase in the share capital at an issue price identical to the earlier increase in capital in March 2018):

In October 2019, another increase in the share capital of Nodthera took place confirming the above valuation at fair value. As a result of this event, the Company's share in the share capital is 8.6%.

value of shares in the balance sheet as at December 31, 2019	23,754,255
change in valuation - impact on the result	928,380
due to revaluation	-
due to changes in the PLN / GBP exchange rate	928,380

On June 3, 2020, the Company's Management Board received information about the acquisition by NodThera Ltd. of financing in connection with the issue of new series B shares with a total value of GBP 44.5 million, which will be taken up by prestigious global biotechnology funds, the so-called blue chips investors, including new investors: Novo Holdings A/S (the investment arm of the pharmaceutical concern Novo Nordisk), Cowen Healthcare Investments and Sanofi Ventures (fund of the pharmaceutical concern Sanofi), as well as its current shareholders 5AM Ventures, F-Prime Capital Partners, Sofinnova Partners and Epidarex Capital. One of the shareholders in Epidarex Capital is Eli Lilly, a global pharmaceutical company that is also a direct shareholder in NodThera.

Financing will be granted in two tranches. Funds in the amount of GBP 20,249,965.22, in connection with the acquisition of 6,817,711 new preferred series B shares, as part of the first financing tranche, were contributed to the company, in accordance with the increase of NodThera's share capital registered on June 2, 2020. Series B shares were taken up at the issue price of GBP 2.9702 per share. The investment agreement signed by NodThera, shareholders and external investors stipulates that after reaching certain milestones in the development of the company's research projects, the share capital of NodTera will be additionally increased by GBP 24,299,835 through the issue of the second tranche of Series B shares in the number of 7,790,656, after an issue price of GBP 3,1191 per share. Pursuant to the investment agreement, the share capital increase referred to above will take place up to June 30, 2021. After the share capital increase under both tranches, the Issuer's share in the share capital of NodThera will be 4.8%.

Reconciliation of the financial data to the carrying amount of shares in NodThera Ltd. included in the Company's financial statements as at December 31, 2020 (after another share capital increase registered on June 2, 2020, described above):

new share issue price (in GBP)	2.9702
average NBP exchange rate of December 31, 2020	5.1327
new share issue price (in PLN)	15.25
number of Company's shares in Nodthera Ltd.	1,910,000

value of shares in the balance sheet as at December 31, 2020	29,118,228
change in valuation - impact on the result	5,363,973
due to revaluation	4,594,704
due to changes in the PLN / GBP exchange rate	769,269

As at December 31, 2020, the Company's share in Nodthera's share capital is 6.07%.

Carrying amount of the Company's shares in Nodthera Ltd.

Balance as at	Balance as at	Balance as at
31/12/2020	31/12/2019	01/01/2019
29,118,228	23,754,255	22,825,875

Fair value of shares in Ryvu Therapeutics S.A. in NodThera Ltd. was determined on the basis of other data that can be observed directly or indirectly (socalled Tier 2).

The Management Board analyzes the factors that may affect the fair value valuation of shares in NodThera on an ongoing basis by analyzing the progress of research work, assessing the Company's competitive environment, as well as the financial and liquidity situation. On this basis, the Management Board of the Company believes that the valuation of the shares held by the Company in NodThera should remain unchanged at the level of the last closed round of financing.

18. Financial assets

The table below presents the individual classes of financial assets and liabilities broken down into levels of the fair value hierarchy as at December 31, 2020. Due to the nature of these items, fair value does not differ significantly from the carrying amount.

P1 Quotes from active markets
P2 Significant Observable Data
P3 Relevant data unobservable

	31/12/2020
	carrying amount	fair value	hierarchy level
Financial assets measured at fair value:
Financial Assets-Nodthera Shares	29,118,228	29,118,228	P2
Financial assets for which fair value is disclosed:
Trade and other receivables	2,369,939	n.a.	n.a.
Other short-term financial assets	24,969,465	n.a.	n.a.
Contract assets	-	n.a.	n.a.
Receivables from share buyback	-	n.a.	n.a.
Financial liabilities at fair value:
n.a.
Financial liabilities for which fair value is disclosed:
Liabilities from deliveries and services	6,277,329	n.a.	n.a.
Investment liabilities	4,584,560	n.a.	n.a.
Interest-bearing loans and credits, including:	2,366,702	n.a.	n.a.
global credit card limit	400,000	n.a.	n.a.
Current portion of interest-bearing loans and borrowings, including:	4,645	n.a.	n.a.
credit card debt	4,645	n.a.	n.a.
Leasing liabilities	5,042,549	n.a.	n.a.

	31/12/2019
	carrying amount	fair value	hierarchy level
Financial assets measured at fair value:
Financial Assets-Nodthera Shares	23,754,255	23,754,255	P2
Financial assets for which fair value is disclosed:
Trade and other receivables	1,475,647	n.a.	n.a.
Other short-term financial assets	-	n.a.	n.a.
Contract assets	360,205	n.a.	n.a.
Receivables from share buyback	2,988,750	n.a.	n.a.
Financial liabilities at fair value:
n.a.
Financial liabilities for which fair value is disclosed:
Liabilities from deliveries and services	16,557,907	n.a.	n.a.
Investment liabilities	5,062,962	n.a.	n.a.
Interest-bearing loans and credits, including:	3,185,808	n.a.	n.a.
global credit card limit	400,000	n.a.	n.a.
Current portion of interest-bearing loans and borrowings, including:	13,930	n.a.	n.a.
credit card debt	13,930	n.a.	n.a.
Leasing liabilities	6,030,953	n.a.	n.a.

	01/01/2019
	carrying amount	fair value	hierarchy level
Financial assets measured at fair value:
Financial Assets-Nodthera Shares	22,825,875	22,825,875	P2
Financial assets for which fair value is disclosed:
Trade and other receivables	11,977,438	n.a.	n.a.
Other short-term financial assets	14,985,926	n.a.	n.a.
Loans granted	67,072	n.a.	n.a.
Financial liabilities at fair value:
n.a.
Financial liabilities for which fair value is disclosed:
Liabilities from deliveries and services	18,706,361	n.a.	n.a.
Investment liabilities	217,559	n.a.	n.a.
Contract liabilities	4,053,135	n.a.	n.a.
global credit card limit	400,000	n.a.	n.a.
Current portion of interest-bearing loans and borrowings, including:	71,437	n.a.	n.a.
credit card debt	71,437	n.a.	n.a.
Leasing liabilities	22,070,778
Contract liabilities	759,510	n.a.	n.a.

19. Other non-financial assets

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
Carrying amount:	PLN	PLN	PLN
Licenses	687,915	768,728	527,500
Insurance	92,012	136,693	140,899
Costs related to subsequent year	446,714	137,182	635,514
Devices qualification	57,421	87,993	338,652
Magazines	597	3,529	-
Stock exchange fee	5,833	-	-
Property tax	2,150	-	-
Market research costs	28,738	21,439	-
Other	229,643	86,789	519,705
	1,551,023	1,242,353	2,162,270

20. Other financial assets

Long term financial assets	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN
Security deposits	85,194	85,193	113,579
	85,194	85,193	113,579

Short term financial assets	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Bonds	24,969,465	-	14,985,926
	24,969,465	-	14,985,926
Bonds issued by Pekao Faktoring Sp. z o.o. guaranteed by Bank
PeKaO S.A. with the maturity date on February 1, 2021.	4,999,145
Bonds issued by Pekao Leasing S.A. guaranteed by Bank PeKaO
S.A. with the maturity date on September 15, 2021. Bonds issued by Pekao Leasing Sp. z o.o. guaranteed by Bank	9,981,490
PeKaO S.A. with the maturity date on June 1, 2021.	9,988,830
	24,969,465

21. Inventories

Balance as at	Balance as at	Balance as at
31/12/2020	31/12/2019	01/01/2019
PLN	PLN	PLN

		1,602,008
1,675,712	1,586,162	1,602,008
	1,675,712	1,586,162

The Company did not recognize any impairment losses on inventories in the period presented in the financial statements. The Company purchases only such goods and materials as may be directly needed for a specific project. Materials are consumed on an ongoing basis.

22. Trade and other receivables

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Trade receivables	2,226,901	1,288,456	11,264,056
The allowance for expected credit losses	(27,321)	(574)	(50,000)
	2,199,580	1,287,882	11,214,056
Tax (VAT) receivables	4,363,033	5,010,965	6,600,000
Other – receivables from employees, security deposits	170,359	187,765	763,382
Receivables from share buyback *	-	2,988,750	-
Grants due	1,215,066	5,205,421	15,871,707
	7,948,038	14,680,783	34,449,145

* Receivables from the repurchase of series "0" shares of Selvita S.A., arising in connection with the division of the Company carried out in October 2019.

22.1. The allowance for expected credit losses on trade receivables and contract assets

In regards to trade receivables and contract assets, the Company estimated the expected credit loss as at 31 December 2020 on the basis of a provision matrix defined based on historical data concerning credit losses. It was recognised that receivables and contract assets of particular customers are characterised by a similar level of risk, they were not divided into groups.

The table below presents the calculation of expected credit losses with respect to trade receivables and contrat assets:

	Period ended 31/12/2020
	Balance of unpaid receivables as at the balance sheet date	The rate of expected credit losses (adjusted)	The amount of the allowance for expected credit losses
Overdue	1,190,967	0.04%	508
1-90 days after the deadline	601,794	0.64%	3,868
91-180 days after the deadline	452,574	2.72%	12,322
181-365 days after the deadline	123,994	8.47%	10,502
More than 365 days after the deadline	121	100.00%	121
Total	2,369,450		27,321

The average payment date of overdue trade receivables is 16 days for the period from 01/01/2020 till 31/12/2020. A new customer's creditworthiness is analysed prior to the entry into a relevant contract. Due to its business profile, the Company cooperates with entities that are known in the industry, which also affects their creditworthiness. The payment terms are set in the offers made to contracting parties.

		Period ended 31/12/2019
	Balance of unpaid receivables as at the balance sheet date	The rate of expected credit losses (adjusted)	The amount of the allowance for expected credit losses
Overdue	1,114,022	0.02%	233
1-90 days after the deadline	513,138	0.02%	103
91-180 days after the deadline	16,278	1.46%	238
181-365 days after the deadline	151	0.00%	0
More than 365 days after the deadline	5,071	0.00%	0
Total	1,648,660		574

The average payment date of overdue trade receivables in the period from 01/01/2019 till 31/12/2019 was 32 days. A new customer's creditworthiness is analysed prior to the entry into a relevant contract. Due to its business profile, the Company cooperates with entities that are known in the industry, which also affects their creditworthiness. The payment terms are set in the offers made to contracting parties.

	Period ended 01/01/2019
	Balance of unpaid receivables as at the balance sheet date	The rate of expected credit losses (adjusted)	The amount of the allowance for expected credit losses
Overdue	6,377,861	0.02%	1,336
1-90 days after the deadline 91-180 days after the deadline 181-365 days after the deadline	3,991,140 778,115 23,322	0.02% 1.46% 0.00%	798 11,355 0
More than 365 days after the deadline	93,618	40.00%	37,447
Total	11,264,056		50,936

The average payment date of overdue trade receivables was 32 days. A new customer's creditworthiness is analysed prior to the entry into a relevant contract. Due to its business profile, the Company cooperates with entities that are known in the industry, which also affects their creditworthiness. The payment terms are set in the offers made to contracting parties.

The allowance for expected credit losses

		Period ended 31/12/2020 Period ended 31/12/2019 Period ended 01/01/2019
	PLN	PLN	PLN
Balance at the beginning of the period	574	50,000	50,000
The allowance for expected credit losses	26,747	574	-
The allowance related to spin-off operations	-	(50,000)	-
Balance at the end of the period	27,321	574	50,000

23. Leases

23.1. The Company as a lessee

The Company has lease agreements for office premises and laboratories, machinery and equipment, office equipment and cars. The leasing period is on average 60 months, except for office equipment, which qualifies as short-term leasing or as low-value contracts.

Some leases include options to extend or terminate the lease. The Company also concludes contracts for an indefinite period. The management board makes a judgment to determine the period over which it can be assumed with reasonable certainty that such contracts will continue (see note 3.8).

The Company also has lease contracts for individual premises with a lease term of 12 months or less, and low value office equipment lease contracts. The Company uses the exemption for short-term leases and leases for which the underlying asset is of low value.

The Company's liabilities under the lease contracts are secured by the lessor's ownership of the subject of the lease. In general, the Company is not entitled to transfer leased assets in subleasing or to assign rights it is entitled to under lease contracts. Some contracts contain requirements for the levels of certain financial indicators.

The following are carrying amounts of the assets due to the right of use (lease agreement) and their changes in the reporting period:

Period ended 31 December 2020	Buildings and premises	Equipment	Vehicles	Total
As at 1 January 2020 after adjustment*	1,424,512	4,203,527	281,789	5,909,828
Purchases (new lease agreements)	-	243,461	-	243,461
Changes in lease agreements	1,161,538	-	-	1,161,538
Depreciation	(1,208,399)	(1,517,054)	(99,199)	(2,824,652)
As at 31 December 2020	1,377,651	2,929,934	182,590	4,490,175

Year ended 31 December 2019	Buildings and premises	Equipment	Vehicles	Total
As at 1 January 2019 after adjustment*	16,955,936	8,567,352	643,687	26,166,975
Purchases (new lease agreements)	-	3,247,738	-	3,247,738
Changes in lease agreements	(13,851,556)	(3,238,583)	(262,699)	(17,352,838)
Splin off OPE	-	(2,654,811)	-	(2,654,811)
Depreciation	(1,679,868)	(1,718,169)	(99,199)	(3,497,236)
As at 31 December 2019 after adjustment*	1,424,512	4,203,527	281,789	5,909,828

The carrying amounts of leasing liabilities and their changes during the reporting period.

	2020
As at 1 January 2020 after adjustment*	6,030,953
Purchases (new lease agreements)	243,461
Changes in lease agreements	1,161,538
Revaluation	579,352
Interest	158,559
Payments	(3,131,314)
As at 31 December 2020	5,042,549
Short-term	2,267,960
Long-term	2,774,589

	2019
As at 1 January 2019 after adjustment*	22,070,778
Purchases (new lease agreements)	3,247,738
Changes in lease agreements	(17,352,838)
Splin off OPE	(2,654,811)
Revaluation	4,098,151
Interest	216,569
Payments	(3,594,634)
As at 31 December 2019 after adjustment*	6,030,953
Short-term	2,474,968
Long-term	3,555,985

* The Company made a presentation adjustment as at January 1, 2019 due to a PLN 4 million reduction in assets and liabilities related to the right to use of premises related to the Selvita S.A. Group before the separation of OPE and reorganization.

The maturity analysis of leasing liabilities is presented in Note 30.8 Liquidity risk.

Amounts of revenues, costs, profits and losses resulting from leasing (regarding buildings and premises and cars) included in the profit and loss account / statement of comprehensive income are presented below:

	01.01.2020-
	31.12.2020
Depreciation of leased assets	(1,307,598)
Interest costs on lease liabilities	(39,333)
Other operating income due to changes in leasing agreements	53,692
Total amount recognized in the income statement / statement of comprehensive income	(1,293,239)

	01.01.2019-
	31.12.2019
Depreciation of leased assets	(1,779,067)
Interest costs on lease liabilities	(140,864)
Other operating income due to changes in leasing agreements	208
Total amount recognized in the income statement / statement of
comprehensive income	(1,919,723)

The total cash outflow from leasing (regarding buildings and premises and cars) was PLN 1,844,183 in the entire year 2019 and PLN 1,428,050 in the entire year 2020.

Amounts of revenues, costs, profits and losses resulting from leasing (regarding equipment) included in the profit and loss account / statement of comprehensive income are presented below:

	01.01.2020-
	31.12.2020
Depreciation of leased assets	(1,517,054)
Interest costs on lease liabilities	(119,226)
Other operating income from changes to lease agreements	1,924
Total amount recognized in the income statement / statement of comprehensive income	(1,634,356)


	01.01.2019-
	31.12.2019
Depreciation of leased assets Interest costs on lease liabilities	(1,718,169) (140,864)

The total cash outflow from leases (regarding machines and equipment) amounted to PLN 1,750,451 in the entire year 2019 and PLN 1,774,495 in the entire year 2020.

24. Share capital

	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN
Registered share capital	7,342,190	6,388,492	6,388,492
	7,342,190	6,388,492	6,388,492

24.1. Share capital as at the end of the reporting period

	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN
Number of shares	18,355,474	15,971,229	15,971,229
Par value per share	0.40	0.40	0.40
Share capital	7,342,190	6,388,492	6,388,492

Share capital structure as at 31 December 2020

Series / issue			Par value of series /
Type of shares (ordinary / registered)	Type of preference	Number of shares	issue
Registered "A" shares	2 votes / 1 share	4,050,000	1,620,000
Ordinary "B" shares	none	1,329,500	531,800
Ordinary "C" shares	none	1,833,000	733,200
Ordinary "D" shares	none	551,066	220,426
Ordinary "E" shares	none	2,700,000	1,080,000
Ordinary "F" shares	none	2,651,891	1,060,756
Ordinary "G1" shares	none	327,886	131,154
Ordinary "G2" shares	none	327,886	131,154
Ordinary "H" shares	none	2,200,000	880,000
Ordinary "I" shares		2,384,245	953,698
Total		18,355,474	7,342,190

Share capital structure as at 31 December 2019

Series / issue	Type of preference	Number of shares	Par value of series /
Type of shares (ordinary / registered)			issue
Registered "A" shares	2 votes / 1 share	4,050,000	1,620,000
Ordinary "B" shares	none	1,329,500	531,800
Ordinary "C" shares	none	1,833,000	733,200
Ordinary "D" shares	none	551,066	220,426
Ordinary "E" shares	none	2,700,000	1,080,000
Ordinary "F" shares	none	2,651,891	1,060,756
Ordinary "G1" shares	none	327,886	131,154
Ordinary "G2" shares	none	327,886	131,154
Ordinary "H" shares	none	2,200,000	880,000
Total		15,971,229	6,388,492

Share capital structure as at 1 January 2019

Series / issue			Par value of series /
Type of shares (ordinary / registered)	Type of preference	Number of shares	issue
Registered "A" shares	2 votes / 1 share	4,050,000	1,620,000
Ordinary "B" shares	none	1,329,500	531,800
Ordinary "C" shares	none	1,833,000	733,200
Ordinary "D" shares	none	551,066	220,426
Ordinary "E" shares	none	2,700,000	1,080,000
Ordinary "F" shares	none	2,651,891	1,060,756
Ordinary "G1" shares	none	327,886	131,154
Ordinary "G2" shares	none	327,886	131,154
Ordinary "H" shares	none	2,200,000	880,000
Total		15,971,229	6,388,492

The company issued series I shares pursuant to Resolution No. 4 of the Extraordinary General Meeting of the Company of July 13, 2020 on increasing the share capital by issuing series I ordinary bearer shares with the exclusion of the subscription right of the existing shareholders in full, on the dematerialisation of the Company's shares series I and rights to those shares (PDA), applying for admission and introduction to trading on the regulated market of the Company's series I shares and rights to these shares (PDA), and on amendments to the Company's Articles of Association, on the basis of which the Company's share capital was increased from the amount PLN 6,388,491.60 (six million three hundred and eighty-eight thousand four hundred and ninetyone PLN 60/100) to the amount of PLN 7,342,189.60 (seven million three hundred and forty-two thousand one hundred eighty-nine PLN 60/100) through the issue of ordinary shares for series I bearer of the Company with a nominal value of PLN 0.40 each. On August 18, 2020, the increase of the Company's share capital was registered by the District Court for Kraków-Śródmieście in Kraków, 11th Commercial Division of the National Court Register.

Series I shares were offered by the Company by way of private subscription within the meaning of Art. 431 § 2 item 1) of the Commercial Companies Code, as part of a public offering as defined in Art. 2 lit. d) Regulation (EU) 2017/1129 of the European Parliament and of the Council of 14 June 2017 on the prospectus to be published in connection with a public offering of securities or their admission to trading on a regulated market and repealing Directive 2003/71/EC, exempt from the obligation to draw up and publish a prospectus or other information (offering) document.

The public offer was addressed to:

1) qualified investors within the meaning of Art. 2 lit. e) the Prospectus Regulation, and

2) investors who are not qualified investors who took up Series I Shares with a total value of at least the equivalent of EUR 100,000 (one hundred thousand euro) per investor for each separate offer,

and therefore the Public Offer did not require the preparation and publication of an issue prospectus, pursuant to Art. 1 clause 4 lit. a) and d) in connection with with art. 1 clause 6 of the Prospectus Regulation.

The issue price of the Series I Shares was set at PLN 60 per share, therefore the total proceeds from the issue, understood as the product of the number of shares covered by the offering and the issue price, amounted to PLN 143,054,700, and the total costs of the offering were PLN 8,226,529. Series I shares

Shareholder structure

Balance as at 31/12/2020

Shareholder	Number of shares	Percentage interest in share capital	Number of votes	Percentage share of voting rights
Paweł Tadeusz Przewięźlikowski	4,990,880	27.19%	8,490,880	37.90%
Bogusław Stanisław Sieczkowski	924,384	5.04%	1,474,384	6.58%
Nationale Nederlanden PTE S.A.	1,594,749	8.68%	1,594,749	7.11%
Other shareholders	10,845,461	59.09%	10,845,461	48.41%
Total	18,355,474	100.00%	22,405,474	100.00%

Balance as at 31/12/2019

Shareholder	Number of shares	Percentage interest in share capital	Number of votes	Percentage share of voting rights
Paweł Tadeusz Przewięźlikowski	4,990,880	31.25%	8,490,880	42.41%
Bogusław Stanisław Sieczkowski Augebit Fundusz Inwestycyjny Zamknięty (directly by	924,384	5.79%	1,474,384	7.36%
Privatech Holdings Limited)	1,039,738	6.51%	1,039,738	5.19%
Nationale Nederlanden PTE S.A.	1,594,749	9.99%	1,594,749	7.97%
Other shareholders	7,421,478	46.46%	7,421,478	37.07%
Total	15,971,229	100.00%	20,021,229	100.00%

Balance as at 01/01/2019

Shareholder	Number of shares	Percentage interest in share capital	Number of votes	Percentage share of voting rights
Paweł Tadeusz Przewięźlikowski	4,990,880	31.25%	8,490,880	42.41%
Bogusław Stanisław Sieczkowski Augebit Fundusz Inwestycyjny Zamknięty (directly and	924,384	5.79%	1,474,384	7.36%
indirectly by Privatech Holdings Limited)	1,039,738	7.55%	1,039,738	5.83%
Nationale Nederlanden PTE S.A.	1,316,969	8.25%	1,316,969	6.58%
Other shareholders	7,699,258	47.16%	7,699,258	37.82%
Total	15,971,229	100.00%	20,021,229	100.00%

24.2. Revaluation reserve

The Company did not create the revaluation reserve in the period presented in the financial statements.

24.3. Other reserve capitals	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Others - incentive program	11,172,000	11,172,000	11,172,000
Total	11,172,000	11,172,000	11,172,000

In 2017, the Company completed the implementation of the incentive program.

Detailed conditions of the incentive program were determined by the Supervisory Board by resolution of September 17, 2015. The company has issued registered bearer subscription warrants. Each subscription warrant was exchangeable for one ordinary share of the Company. The number of warrants in the incentive program was 627,814 shares. The receiving warrant did not pay or receive any monetary amounts. The rights to subscribe for shares arising from the warrants were exercised on two dates, i.e. until February 29, 2016 and February 28, 2017.

24.4. Share premium	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN
Share premium	159,680,803	159,680,803	159,680,803
including the surplus on the issue of shares above their nominal value, "H" series ordinary shares	134,200	134,200	-
including issue costs, "H" series ordinary shares	(4,295,093)	(4,295,093)	-
including surplus from issue of shares above their nominal value "I" series ordinary shares	142,101,002	-	-
including issue costs, "I" series ordinary shares	(8,226,529)	-	-
Transfer of result from previous years due to the split	(10,331,325)	(10,331,325)	8,564,017
Total Reserve Capital	279,063,058	145,188,585	168,244,820

25. First-time adoption of IFRS

The financial year ended December 31, 2020 was the first year for which the Company prepared its financial statements in accordance with IFRS and related interpretations adopted by the European Union. IFRS transition date for Ryvu Therapeutics S.A. is January 1, 2019 and the opening balance has been prepared for that day.

Entities that prepare financial statements according to IFRS for the first time apply the guidelines of International Financial Reporting Standard 1 ("IFRS 1") "Application of International Financial Reporting Standards for the first time". Pursuant to IFRS 1, these financial statements have been prepared as if the Company had always applied IFRS EU as at the reporting date, together with a statement of full compliance with all IFRS standards.

The company applied its obligatory and voluntary exemptions from the application of selected EU IFRSs specified in IFRS 1. They are described below.

The company applied the following mandatory exceptions:

Estimates

The estimates as at January 1, 2019 and December 31, 2019 are consistent with the estimates made for the same dates in accordance with PAS after adjustments reflecting any differences in accounting policies. The company has for the first time used estimates for the following transactions, for which execution was not required under PAS, but is required under IFRS:

Share-based payments,
Valuation of financial assets measured at fair value,
Assets and liabilities due to the right of use.

Classification and valuation of financial instruments

An entity applying IFRS for the first time is required to assess whether a financial asset meets the conditions on the basis of facts and circumstances that exist at the date of transition to IFRS. As at the date of transition to IFRS, if the assessment of the changed value of money over time is impracticable on the basis of facts and circumstances as at the date of transition to IFRS, the Company assesses the contractual cash flows specific to that financial asset based on facts and circumstances as at transition to IFRS without taking into account the requirements related to the change in the time value of money.

In addition, the Company applied the following voluntary exemptions:

Investments in subsidiaries, joint ventures and associates

If the entity applying IFRS for the first time measures an investment in a subsidiary, joint venture or associate at cost, as at the date of transition to IFRS, it can measure such investment at cost (determined in accordance with IAS 27 Consolidated and separate financial statements) or assumed cost (fair value or value previously disclosed according to UoR as at the date of transition to IFRS).

The company decided to use this exemption for the valuation of investments in related entities as at January 1, 2019, using the valuation established in accordance with the Act on the Act on the date of January.

Leases

When applying IFRS, the company assessed for the first time whether a given contract existing at the date of transition to IFRS includes leasing based on facts and circumstances as at that date.

When applying IFRS for the first time, the Company as a lessee recognized lease liabilities and asset components under the right of use, applying the following practical approaches to all its leases:

a) the lease liability was measured on the date of transition to IFRS. The company measured the lease liability at the present value of other lease payments, discounted using the lessee's marginal interest rate on the date of transition to IFRS;

b) the asset under the right of use was measured on the date of transition to IFRS in an amount equal to the liability under the lease, adjusted for the amount of all prepaid and accrued lease payments relating to that lease, recognized in the statement of financial position immediately before the date of transition to IFRS.

c) IAS 36 was applied to the assets due to the right of use on the date of transition to IFRS.

The Company also decided to take advantage of exemptions for leasing contracts whose lease period at the start date is 12 months or less and which do not include a purchase option ("short-term leasing") and leasing contracts for which the underlying asset is of low value (" low-value assets "), and also excluded initial direct costs from the valuation of the asset due to the right of use on the date of transition to IFRS. In addition, the Company used the knowledge after the fact, e.g. in the case of determining the lease period, if the contract provided for the possibility of extending the lease or terminating the lease. The company applied one discount rate for a portfolio of leases with similar characteristics. The discount rates adopted by the Company for the purpose of valuation in accordance with IFRS 16 were based on reference interest rates on loans on the interbank market, respectively for a given currency, corrected by the margin used by the Company to incur debt. Discount rates include the maturity and currency of the contracts and are not differentiated by type of assets. The weighted average discount rate adopted at the time of the first application of the standard was 1.9%, while the dominant currency of the contracts identified was the euro.

In addition, the Company did not decide to apply a voluntary exemption consisting in the valuation of non-financial fixed assets as at the date of transition to IFRS 1 at the assumed cost at the level of fair value, because as a result of the analysis it found that the value of non-financial fixed assets according to IFRS corresponds to their carrying amount determined as a cost initial reduced by depreciation charges and any impairment losses in accordance with the Accounting Act.

RECONCILIATION OF THE STATEMENT OF FINANCIAL POSITION BY POLISH ACCOUNTING STANDARDS AND IFRS PREPARED AS AT JANUARY 1, 2019

	Balance as at		Balance as at	Balance as at
	01/01/2019	adjustments*	01/01/2019**	01/01/2019**
	Polish Accounting		Effect of	IFRS
ASSETS	Standards		transition to IFRS
Non-current assets
Tangible fixed assets	39,713,134	2,3	19,392,274	59,105,408
Other Intangible assets	2,383,664		-	2,383,664
Financial assets-Shares in Nodthera	678,910	5	22,146,965	22,825,875
Deferred Tax Asset	6,599,616		-	6,599,616
Other financial assets	113,579		-	113,579
Total non-current assets	49,488,903		41,539,239	91,028,142
			-
Current assets
Inventory	1,602,008		-	1,602,008
Short-term receivables	18,577,438	1	15,871,707	34,449,145
Contract assets	-		596,421	596,421
Other financial assets	15,052,998		-	15,052,998
Other assets	18,033,977	1	(15,871,707)	2,162,270
Cash and other monetary assets	94,858,075		-	94,858,075
Total current assets	148,124,496		596,421	148,720,917
Total assets	197,613,399		42,135,660	239,749,059
EQUITY AND LIABILITIES
Equity
Share capital	6,388,492		-	6,388,492
Share premium	168,244,820		-	168,244,820
Capital resulting from the spin-off	-	6	11,172,000	11,172,000
Retained earnings / Accumulated losses	(23,056,237)		7,586,900	(15,469,337)
Net profit / (loss) for the period	-		-	-
Total equity	151,577,075		18,758,900	170,335,975
Long-term liabilities
Bank loans and credits	3,171,878		-	3,171,878
Lease liabilities	2,723,811	2	13,749,798	16,473,609
Retirement provision	118,023		-	118,023
Deferred tax liability	29,989	4,5	4,400,236	4,430,225
Deferred income	10,362,746		-	10,362,746
Total long-term liabilities	16,406,447		18,150,034	34,556,481
Short-term liabilities
Trade and other liabilities	20,317,336		-	20,317,336

Contract liabilities	-		759,510	759,510
Bank loans and credits	881,257		-	881,257
Lease liabilities	1,355,323	2	4,241,846	5,597,169
Deferred income and accrued expenses	2,978,966		-	2,978,966
Deferred income	4,096,995	1	225,370	4,322,365
Total short-term liabilities	29,629,877		5,226,726	34,856,603
Total liabilities	46,036,324		23,376,760	69,413,084
Total equity and liabilities	197,613,399		42,135,660	239,749,059

** data as at January 1 and December 31, 2019 have been restated (see Note 13.2)

* Adjustments:

1. Reclassification of receivables from subsidies

- Change in the presentation of amounts due from subsidies calculated in proportion to the eligible costs incurred in the amount of PLN 15,871,707.

2. Application of IFRS 16

- Valuation of tangible assets used based on lease contracts in the amount of PLN 17,991,664 and adjustment of long-term leasing liabilities in the amount of PLN 13,749,798 and short-term leasing liabilities in the amount of PLN 4,241,846.

3. Adjustment of depreciation of low-value fixed assets

- Adjustment of the depreciation calculation of low-value fixed assets from a one-off method to a straight-line method in the amount of PLN 1,400.630.

4. Adjustment for deferred tax

- Adjustment of the deferred tax provision related to the valuation of shares in Nodthera in the amount of PLN 4,207,923 and resulting from the change in the method of depreciation of low value fixed assets in the amount of PLN 192,312.

5. Valuation of shares in Nodthera (Note 17)

6. Adjustment in connection with the transformation to IFRS as a result of settlement of the option program

- Adjustment of remuneration costs in connection with the incentive program carried out in 2015-2016 in the amount of PLN 11,172,000.

RECONCILIATION OF THE STATEMENT OF FINANCIAL POSITION BY POLISH ACCOUNTING STANDARDS AND IFRS PREPARED AS AT DECEMBER 31, 2019

	Balance as at 31/12/2019		Balance as at 31/12/2019**	Balance as at 31/12/2019**
	Polish Accounting	adjustments*	Effect of
	Standards		transition to IFRS	IFRS
ASSETS
Non-current assets
Tangible fixed assets	63,556,984	2,3	2,632,497	66,189,481
Other Intangible assets Financial assets-Shares in Nodthera	2,923,654 678,910	5	- 23,075,345	2,923,654 23,754,255
Deferred Tax Asset	350,427	4	350,363	700,790
Other financial assets	85,194		-	85,194
Total non-current assets	67,595,169		26,058,205	93,653,374
Current assets
Inventory	1,586,162		-	1,586,162
Trade and other receivables	9,475,361	1	5,205,421	14,680,782
Contract assets	-	8	360,205	360,205
Other financial assets	6,860,154	1.8	(5,617,801)	1,242,353
Cash and other monetary assets	72,106,928		-	72,106,928
Total current assets	90,028,605		(52,175)	89,976,430
Total assets	157,623,774		26,006,030	183,629,804
EQUITY AND LIABILITIES
Equity
Share capital	6,388,492		-	6,388,492
Kapitał zapasowy	145,188,585		-	145,188,585
Capital resulting from the split	(14,418,357)		-	(14,418,357)
Capital resulting from the spin-off	-	6	(320,977,452)	(320,977,452)
Other reserve capitals	-	7	11,172,000	11,172,000
Retained earnings / Accumulated losses	-		7,586,901	7,586,901
Net profit / (loss) for the period	(35,998,690)	6	321,638,700	285,640,010
Total equity	101,160,030		19,420,149	120,580,179
Long-term liabilities
Bank loans and credits	2,362,058		-	2,362,058
Lease liabilities	2,927,882	2	628,103	3,555,985
Retirement provision	188,159		-	188,159
Deferred tax liability	350,427	4,5	4,793,286	5,143,713
Deferred income	21,183,710		-	21,183,710
Total long-term liabilities	27,012,236		5,421,389	32,433,625
Short-term liabilities
Trade and other liabilities	22,636,132		-	22,636,132
Bank loans and credits	823,750		-	823,750
Lease liabilities	1,698,936	2	776,032	2,474,968
Deferred income and accrued expenses	4,292,690	1	388,459	4,681,149
Total short-term liabilities	29,451,508		1,164,491	30,615,999
Total liabilities	56,463,744		6,585,880	63,049,624
Total equity and liabilities	157,623,774		26,006,030	183,629,804

** data as at January 1 and December 31, 2019 have been restated (see Note 13.2)

* Adjustments:

1. Reclassification of receivables from subsidies

- Change in the presentation of amounts due from subsidies calculated in proportion to the eligible costs incurred in the amount of PLN 5,205,421.

2. Application of IFRS 16

- Valuation of tangible assets used based on lease contracts in the amount of PLN 2,539,129 and adjustment of long-term leasing liabilities in thamount of PLN 628,103 and short-term leasing liabilities in the amount of PLN 776,032.

3. Adjustment of depreciation of low-value fixed assets

- Adjustment of the depreciation calculation of low-value fixed assets from a one-off method to a straight-line method in the amount of PLN 93,377.

4. Adjustment for deferred tax

- Adjustment of deferred tax assets from the change in depreciation of low-value assets and subsidy revenues from depreciation of low-value assets in the amount of PLN 7,828 and adjustment of deferred tax assets resulting from the application of IFRS 16 in the amount of PLN 342,535.

- Adjustment of the provision for deferred tax charged in connection with the application of IFRS 16 in the amount of PLN 364,851.

5. Valuation of shares in Nodthera (Note 17)

6. Effect of separating OPE (Note 16)

7. Adjustment in connection with the transformation to IFRS as a result of settlement of the option program

- Adjustment of remuneration costs in connection with the incentive program carried out in 2015-2016 in the amount of PLN 11,172,000.

8. Presentation of contract asset

- Change in the presentation of contractual receivables in the amount of PLN 360,205.

RECONCILIATION OF THE PROFITS AND LOSS ACCOUNT ACCORDING TO POLISH ACCOUNTING STANDARDS AND IFRS FOR THE PERIOD FROM 1 JANUARY 2019 TO 31 DECEMBER 2019

	Balance as at 31/12/2019		Balance as at 31/12/2019		Balance as at 31/12/2019
	Polish Accounting Standards	adjustments*	Effect of transition to IFRS	Presentation of spin off activities [adjustment 6]	IFRS
Continuing operations
Sales revenue	42,567,163	6	-	(38,768,832)	3,798,331
Grant income	31,187,013	1,6	(52,175)	(1,212,902)	29,921,936
Other operating revenue	790,484	2,6	208	(372,226)	418,466
Total operating revenue	74,544,660		(51,967)	(40,353,960)	34,138,733
Amortization and depreciation	(9,109,107)	2,3,6	(1,733,785)	2,854,257	(7,988,635)
Consumption of materials and materials	(20,615,401)	6	-	7,811,655	(12,803,746)
External services	(44,344,098)	1,2,6	1,844,183	15,402,379	(27,097,536)
Salaries	(41,174,895)	6	-	12,707,007	(28,467,888)
Taxes and charges	(655,972)	6	-	347,999	(307,973)
Other expenses	(3,648,738)	6	-	872,676	(2,776,062)
Other operating expenses	(135,549)	6	-	53,409	(82,140)
Total operating expenses	(119,683,760)		110,398	40,049,382	(79,523,980)
(Operating) loss	(45,139,100)		58,431	(304,578)	(45,385,247)
Financial revenue	9,534,855	6,8	(8,320,928)	(307,336)	906,591
Financial expenses	(424,435)	2	(134,682)	-	(559,117)
(Loss) on business activities	(36,028,680)		(8,397,179)	(611,914)	(45,037,773)
Valuation of Nothera shares	-	5	928,380	-	928,380
(Loss) before income tax	(36,028,680)		(7,468,800)	(611,914)	(44,109,394)
Income tax expense	29,990	4	(190,880)	-	(160,890)
Net (loss) on continuing operations	(35,998,690)		(7,659,680)	(611,914)	(44,270,284)
Discontinued operations
Net profit on discontinued operations Dividend on discontinued operations	- -	6 8	- 8,320,928	611,914 -	611,914 8,320,928
Profit on the spin-off	-	7	320,977,452	-	320,977,452
NET (LOSS) / PROFIT	(35,998,690)		321,638,700	-	285,640,010

TOTAL INCOME FOR THE PERIOD	(35,998,690)		321,638,700	-	285,640,010

* Adjustments:

Reclassification of subsidy income
Change in the presentation of revenues from subsidies accrued from the depreciation of low-value fixed assets in the amount of PLN 52.175.

2. Adoption of IFRS 16

- Adjustment of depreciation of usage rights in the amount of PLN 1,827,162 and the costs of external services in the amount of PLN 1,844,183.

- Adjustment of other operating income in the amount of PLN 208.

- Adjustment of financial costs in the amount of PLN 134,682.

3. Adjustment of depreciation of low-cost fixed assets

- Correction of the depreciation calculation of low-value fixed assets from a one-off method to a straight-line method in the amount of PLN 93,377.

4. Income tax adjustment

- Correction of the calculation of deferred income tax calculated on the change in the depreciation of low-value funds and income from subsidies on the depreciation of low-value funds in the amount of PLN 7,828 and the calculation of deferred income tax in the depreciation and adjustment of services resulting from the application of IFRS 16 in the amount of PLN 22,316.

5. Valuation of shares in associates (Note 17)

- Valuation of shares in Nodthera according to the average exchange rate of the National Bank of Poland as at 31.12.2019.

6. Presentation of spin-off activities

- Change in the presentation of revenues related to spin-off operations in the amount of PLN 38,786,832.

Change in the presentation of revenues from subsidies related to spin-off operations in the amount of PLN 1,212,902.
Change in the presentation of other operating income related to spin-off operations in the amount of PLN 372,226.
Change in the presentation of depreciation relating to spin-off operations in the amount of PLN 2,854,257
Change in the presentation of the consumption of raw materials and materials related to the spin-off activity in the amount of PLN 7,811,655.
Change in the presentation of external services related to spin-off operations in the amount of PLN 15,402,379.
Change in the presentation of employee benefits related to spin-off activities in the amount of PLN 12,707,007.
Change in presentation of taxes and fees related to spin-off operations in the amount of PLN 347,999.
Change in the presentation of other costs related to spin-off operations in the amount of PLN 872.676.
Change in the presentation of other operating costs related to spin-off operations in the amount of PLN 53.409.
Change in the presentation of financial income related to spin-off operations in the amount of PLN 307.336.

7. Effect of separating of the OPE

The effect of the separation of OPE: The difference to the Accounting Act resulted from a different treatment of IFRS transactions, i.e. in accordance with IFRIC 17. The division of the Company, in the light of IFRIC 17, was a transfer of non-cash assets to the Company's shareholders (and thus a noncash dividend payment to shareholders in correspondence with equity) and the application of this standard resulted in recognition in a separate item in the profit and loss account of "Separation profit" in the amount of PLN 321 million in 2019, which is the difference between the fair value of all shares of Selvita CRO SA (currently Selvita S.A.), calculated as the product of the number of shares and the closing price from the first day of listing on the WSE: October 16, 2019, and the net asset value transferred in the form of an organized part of the enterprise.

	Computation	Value in PLN
Fair value	21*15.971.229 shares =	335,395,809
Net assets of OPE		14,418,357
Gain on spin-off		320,977,452

The impact on the Company's equity as a result of this recognition of the transaction was zero PLN. It was a non-cash item and was a direct result of the division and receipt of 1:1 ratio shares of Selvita CRO S.A. (currently Selvita S.A.) by the shareholders of Ryvu Therapeutics S.A.

8. Presentation of the dividend paid from Selvita Services Sp. z o.o. to the Company.

RECONCILIATION OF THE STATEMENT OF CASH FLOWS ACCORDING TO POLISH ACCOUNTING STANDARDS AND IFRS FOR THE PERIOD FROM 1 JANUARY 2019 TO 31 DECEMBER 2019

	Balance as at 31/12/2019 Polish Accounting	adjustment*	Balance as at 31/12/2019 Effect of transition	Balance as at 31/12/2019 IFRS
	Standards		to IFRS
Cash flows from operating activities Profit / (loss) for the period	(35,998,690)		321,638,700	285,640,010

Adjustments: Valuation of shares in Nodthera		5	(928,380)	(928,380)
Amortization and depreciation and impairment losses on fixed
assets	9,109,107	3	(1,120,472)	7,988,635
Interest and profit-sharing (dividends), net	(9,145,892)		-	(9,145,892)
Profit on the spin-off		6	(320,977,452)	(320,977,452)
Change in receivables	1,006,389	7,8	10,666,286	11,672,675
Change in inventory Change in short-term liabilities and provision excluding credits	(682,736)		-	(682,736)
and loans	(1,088,984)		-	(1,088,984)
Change in deferred income	18,944,892	1	(4,284,447)	14,660,445
Change in deferred tax	454,950	2,4	(615,840)	(160,890)
Change in other assets	-	2,4,7,8	(4,378,395)	(4,378,395)
Net cash flows from operating activities	(17,400,964)		-	(17,400,964)
- from continued operations	(24,253,257)		4,831,461	(19,421,795)
- from discontinued operations	6,852,293		(4,831,462)	2,020,831
Cash flows from investing activities
Disposal of tangible and intangible fixed assets	80,000		-	80,000
Purchase of tangible and intangible fixed assets	(23,994,850)		-	(23,994,850)
Purchase / (disposal) of other financial assets	14,928,600		-	14,928,600
Acquisition of shares in connection with the spin-off of OPE	- -	10 9	(2,988,750) 8,320,928	(2,988,750) 8,320,928
Dividends received Interest received	1,042,764		-	1,042,764
Repayment of loans	1,709		-	1709
Loans granted	5,271		-	5,271
Net cash flows from investing activities	(7,936,506)		5,332,178	(2,604,328)
- from continued operations	(4,043,109)		(2,988,750)	(7,031,859)
- from discontinued operations	(3,893,397)		8,320,928	4,427,531
Cash flows from financing activities
Repayment of finance lease liabilities	(1,704,306)		-	(1,704,306)
Proceeds from credits and loans	57,508		-	57,508
Repayment of credits and loans	(881,259)		1	(881,258)
Dividends received	8,320,928	9	(8,320,928)	-
Purchase of shares of related parties	(2,988,750)	10	2,988,750	-
Interest paid	(217,800)		-	(217,800)
Net cash flows from financing activities	2,586,321		(5,332,177)	(2,745,856)
- from continued operations	(1,629,672)		-	(1,629,672)
- from discontinued operations	4,215,993		(5,332,177)	(1,116,184)
Net increase / (decrease) in cash and cash equivalents	(22,751,148)		-	(22,751,148)
Cash and cash equivalents at the beginning of the period	94,858,075		-	94,858,075
Cash and cash equivalents at the end of the period	72,106,927		-	72,106,927

* Adjustments:

1. Reclassification of subsidy income

- Change in the presentation of revenues from subsidies accrued from the depreciation of low-value fixed assets in the amount of PLN 52,175.

2. Application of IFRS 16

- Valuation of tangible assets used based on lease contracts in the amount of PLN 5,561,904 and adjustment of long-term leasing liabilities in the amount of PLN 4,155,393 and short-term leasing liabilities in the amount of PLN 1,523,963.

3. Adjustment of depreciation of low-value fixed assets

- Adjustment of the depreciation calculation of low-value fixed assets from a one-off method to a straight-line method in the amount of PLN 93,377.

4. Adjustment for deferred tax

- Adjustment of deferred tax asset from changes in the value of amortization of low-value funds and revenues from subsidies accrued from amortization of low-value funds in the amount of PLN 7,828 and adjustment of the deferred tax asset resulting from the application of IFRS 16 in the amount of PLN 342,535.

5. Valuation of shares in associates (Note 17)

6. Effect of separating OPE (Note 16)

7. Reclassification of subsidies

- Change in the presentation of receivables from subsidies calculated in proportion to the eligible costs incurred in the amount of PLN 5,205,421.

8. Reclassification of receivables from settlement of long-term contracts

- Change in the presentation of contractual receivables in the amount of PLN 360,205.

9. Reclassification of dividends received in the amount of PLN 8,320,928

10. Reclassification of purchase of shares of related entities in the amount of PLN 2,988,750

26. Credit facilities and loans and other sources of financing

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Uncollateralized:
Overdraft facilities (i)	-	-	-
Used credit card limits (ii)	4,645	13,930	71,437
	4,645	13,930	71,437
Collateralized:
Bank loans (iii)	2,362,057	3,171,878	3,981,698
	2,362,057	3,171,878	3,981,698
Total:	2,366,702	3,185,808	4,053,135
Current liabilities	814,465	823,750	881,257
Non-current liabilities	1,552,237	2,362,058	3,171,878
	2,366,702	3,185,808	4,053,135

26.1. Loan agreements

(i) The Company does not have any open overdraft facilities.

(ii) The balance of debt as at 31/12/2020 results from the use of the limit on credit cards in the amount of PLN 4,645.

(iii) The company has a mortgage loan for the purchase of a construction plot in Bank PKO BP. The loan was concluded on December 13, 2016 for a period of 7 years.

The interest rate is variable and is formed as the sum of WIBOR1M + bank margin.

The loan is secured by a mortgage entry in the amount of PLN 8,403,000, a blank promissory note for PLN 2,362,057 and a contractual right of set-off to PLN 2,362,057.

26.2. Breaches of covenants

None.

27. Provisions

None.

28. Trade and other liabilities

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Trade liabilities Investment liabilities	6,260,821 4,584,560	13,350,186 5,062,962	16,690,287 217,559
Liabilities due to taxes, insurance (social security, personal income tax, PFRON) CIT liability	666,543 -	1,015,263 -	1,565,791 45,184
Liabilites due to salaries and wages and other liabilities to employees Other non-financial liabilities	54 16,454	11,911 3,195,810	523,685 1,274,830
	11,528,432	22,636,132	20,317,336

The average payment term for purchases of goods and materials is two months. Following its due date, interest usually are not accrued on outstanding liabilities.The Company has a financial risk management policy in place, ensuring that its liabilities are paid on time.

29. Liabilities due to retirement benefits

Balance as at 31/12/2020

Item	Provisions for retirement benefits	Total
Provisions at the beginning of the period	188,159	188,159
Increases:	46,807	46,807
- provisions recognized in profit and loss account in current period	46,807	46,807
Provisions at the end of the period, including:	234,966	234,966
- long-term	234,966	234,966
- short-term	-	-

Balance as at 31/12/2019

Item	Provisions for retirement benefits	Total
Provisions at the beginning of the period	118,023	118,023
Increases:
- provisions recognized in profit and loss account in current period	70,136	70,136
Provisions at the end of the period, including:	188,159	188,159
- long-term	188,159	188,159
- short-term	-	-

Balance as at 01/01/2019

Item	Provisions for retirement benefits	Total
Provisions at the beginning of the period	118,023	118,023
Provisions at the end of the period, including:	118,023	118,023
- long-term	118,023	118,023
- short-term	-	-

30. Financial instruments

30.1. Capital risk management

The Company manages its capital to ensure that it will be able to continue as a going concern while maximizing its profitability through optimization of the debt to equity ratio.

The capital structure as well as the level and maturity of liabilities are reviewed on a regular basis. The said reviews comprise analyses of the cost of capital and the risk associated with its individual categories.

The key items analysed by the Company are:

• cash and cash equivalents, as disclosed in Note 35,

• equity, including reserve capitals and retained earnings, as disclosed in Note 24.

The Company is not subject to any external capital requirements except for the one imposed by Article 396.1 of the Code of Commercial Companies, which the parent is obliged to comply with, whereby supplementary capital has to be created for purposes of offsetting losses. No less than 8% of the profit for the financial year has to be transferred to the supplementary capital until its value reaches at least one third of the share capital. That part of the supplementary capital (retained earnings) may not be distributed to the shareholders.

30.1.1. Net debt to equity ratio

The Company reviews its capital structure periodically. The said reviews comprise analyses of the cost of capital and the risks associated with each category of capital.

Balance as at	Balance as at	Balance as at
31/12/2020	31/12/2019	01/01/2019
PLN	PLN	PLN
(71,919,509)	(63,049,627)	(69,413,084)
136,218,238	72,106,927	94,858,075
64,298,729	9,057,300	25,444,991
223,720,759	120,580,176	170,335,975
0.29	0.08	0.15

(i) Debt comprises long- and short-term debt.

(ii) Equity comprises the equity presented in the statement of financial position.

The achieved debt ratio is within the limits expected and accepted by the Management Board.

Additionally, it should be remembered that the Company has short-term investments presented in the item Other financial assets (Note 20), which concern funds invested in liquid financial instruments issued by leading financial institutions from the Polish market.

30.2. Categories of financial instruments

The company is exposed to risks related to financial instruments. The risks to which it is exposed are:

market risk including currency risk and interest rate risk,
credit risk and
liquidity risk.

Individual types of risk are discussed in the following Notes.

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Financial assets
Financial instruments measured at amortized cost method:	164,687,543	81,674,173	137,110,415
Loans granted (Note 18)	-	-	67,072
Other short term financial assets (Note 20)	24,969,465	-	14,985,926
Other financial asets - deposits (Note 20)	85,194	85,193	113,579
Cash (Note 35)	136,218,238	72,106,927	94,858,075
Trade and other receivables (Note 22)	3,414,646	6,493,303	27,085,763
Receivables from share buyback (Note 22)	-	2,988,750	-
Financial assets at fair value through profit or loss	29,118,228	23,754,255	22,825,875
Other financial assets - Nodthera shares (Note 17)	29,118,228	23,754,255	22,825,875
Financial liabilities
Financial instruments measured at amortized cost method:	18,254,632	31,076,463	26,658,153
Interest bearing credit facilities and loans (Note 26)	2,366,702	3,185,808	4,053,135
Finance lease liabilities (Note 30.8)	5,042,549	6,030,953	22,070,778
Trade and other liabilities (Note 28)	10,845,381	18,413,148	16,907,846

30.3. Financial risk management objectives

Credit, liquidity and market risks (including mainly currency risk and interest rate risk) occur in the ordinary course of the Company's business. Financial risk management at the Company is primarily aimed to minimize the effect of market factors, such as foreign exchange and interest rates, on the key financial parameters approved in the Company's budget for the year (profit and cash flows) with the use of natural hedges.

30.4. Market risk

The Company's activities expose it to currency risk (see Note 30.5) and interest rate risk (see Note 30.6). The Company does not use any derivative instruments for purposes of currency or interest rate risk management as natural hedges are sufficient to minimize the risk it is exposed to. Exposure to all market risk categories is measured by means of a sensitivity analysis.

30.5. Foreign currency risk management

The Company enters into certain transactions denominated in foreign currencies. Hence, it is exposed to the risk of changes in foreign exchange rates. The said risk is managed by means of natural hedges.

The carrying amounts of the Company's foreign currency monetary assets and liabilities as at the end of the reporting period:

	Liabilities		Assets
Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
PLN	PLN	PLN	PLN	PLN	PLN
4,124,574	5,415,515	10,202,978	9,043,845	10,062,383	6,926,367
342,910	1,924,988	958,730	14,409,699	849,730	118,088
263,812	450,795	157,865	710,949	730,122	2,598

30.5.1. Sensitivity to currency risk

The Company is mainly exposed to risk related to EUR and USD.

The degree of sensitivity of the Company to a 15% increase and decrease of the PLN exchange rate for foreign currencies is presented in the table below. 15% is the sensitivity rate used in internal currency risk analyzes for top management and reflects management's assessment of possible changes in foreign exchange rates. The sensitivity analysis covers only unsettled monetary items denominated in foreign currencies and corrects the currency conversion at the end of the accounting period by a 15% change in exchange rates. A positive value in the table below indicates an increase in profit and an increase in equity accompanying the strengthening of the PLN exchange rate for foreign currencies by 15%. In the case of a 15% weakening of PLN against a given foreign currency, this value would be negative, and the impact on profit and equity would be the opposite.

			EUR Effect		USD Effect
		Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
		PLN	PLN	PLN	PLN	PLN	PLN
ASSETS
Exchange rate increase	15%	1,356,577	1,509,357	1,038,955	2,161,455	127,460	17,713
Exchange rate increase	10%	904,384	1,006,238	692,637	1,440,970	84,973	11,809
Exchange rate increase	5%	452,192	503,119	346,318	720,485	42,487	5,904
Exchange rate decrease	-5%	(452,192)	(503,119)	(346,318)	(720,485)	(42,487)	(5,904)
Exchange rate decrease	-10%	(904,384)	(1,006,238)	(692,637)	(1,440,970)	(84,973)	(11,809)
Exchange rate decrease	-15%	(1,356,577)	(1,509,357)	(1,038,955)	(2,161,455)	(127,460)	(17,713)
LIABILITIES
Exchange rate increase	15%	618,686	812,327	1,530,447	51,437	288,748	143,809
Exchange rate increase	10%	412,457	541,551	1,020,298	34,291	192,499	95,873
Exchange rate increase	5%	206,229	270,776	510,149	17,146	96,249	47,936
Exchange rate decrease	-5%	(206,229)	(270,776)	(510,149)	(17,146)	(96,249)	(47,936)
Exchange rate decrease	-10%	(412,457)	(541,551)	(1,020,298)	(34,291)	(192,499)	(95,873)
Exchange rate decrease	-15%	(618,686)	(812,327)	(1,530,447)	(51,437)	(288,748)	(143,809)
EFFECT ON PROFIT
Exchange rate increase	15%	737,891	697,030	(491,492)	2,110,018	(161,289)	(126,096)
Exchange rate increase	10%	491,927	464,687	(327,661)	1,406,679	(107,526)	(84,064)
Exchange rate increase	5%	245,964	232,343	(163,831)	703,339	(53,763)	(42,032)
Exchange rate decrease	-5%	(245,964)	(232,343)	163,831	(703,339)	53,763	42,032
Exchange rate decrease	-10%	(491,927)	(464,687)	327,661	(1,406,679)	107,526	84,064
Exchange rate decrease	-15%	(737,891)	(697,030)	491,492	(2,110,018)	161,289	126,096

The Company's exposure to currency risk changes throughout the year depending on the volume of foreign currency transactions. Nevertheless, the above sensitivity analysis may be regarded as representative for determination of the currency risk exposure.

30.6. Interest rate risk management

The Company is exposed to interest rate risk resulting from floating rate lease agreements. Hedging activities are subject to regular reviews so that they are brought into line with the current interest rate situation and predefined risk appetite, and to ensure that an optimum hedging strategy is in place.

30.6.1. Sensitivity to changes in interest rates

The sensitivity analyzes presented below are based on the degree of exposure to interest rate risk of financial instruments (liabilities arising from leasing and loan agreements) as at the balance sheet date. In the case of liabilities with a variable interest rate, it is assumed for the purposes of the analysis that the amount of unpaid liabilities at the balance sheet date was unpaid for the whole year. Internal analyzes of interest rate risk for key management members use up and down fluctuations of 50 basis points, which reflects management's assessment of the likely change in interest rates.

31 December 2020
	< 1 year	1–2 years	2-3 years	3-4 years	4-5 years	>5 years	Total
Lease liabilities	2,267,960	1,774,649	797,623	202,317	-	-	5,042,549
Bank loan for the amount of PLN 5,601 thousand	809,820	809,820	742,417	-			2,362,057
	< 1 year	1–2 years	2-3 years	3-4 years	4-5 years	>5 years	Total
Cash	136,218,238						136,218,238
31 December 2019
	< 1 year	1–2 years	2-3 years	3-4 years	4-5 years	>5 years	Total
Lease liabilities	2,474,968	2,128,558	1,116,127	236,506	74,794		6,030,953
Bank loan for the amount of PLN 5,601 thousand	809,820	800,196	800,196	761,666	-		3,171,878
	< 1 year	1–2 years	2-3 years	3-4 years	4-5 years	>5 years	Total
Cash	72,106,927						72,106,927
1 January 2019
	< 1 year	1–2 years	2-3 years	3-4 years	4-5 years	>5 years	Total
Lease liabilities	5,597,169	8,236,805	4,942,083	2,759,075	535,646		22,070,778
Bank loan for the amount of PLN 5,601 thousand	809,820	800,196	800,196	800,196	771,290		3,981,698
	< 1 year	1–2 years	2-3 years	3-4 years	4-5 years	>5 years	Total
Cash	109,911,073						109,911,073

The interest rate on financial instruments with a variable interest rate is updated in periods of less than one year. Interest on financial instruments with a fixed interest rate is constant throughout the period until the maturity / maturity of these instruments. Other financial instruments of the Company which are not included in the above tables are not interest bearing and are therefore not subject to interest rate risk.

Interest rate risk - sensitivity to changes

The table below presents the sensitivity of gross profit (loss) to reasonably possible changes in interest rates, assuming that other factors remain unchanged (in connection with liabilities with a variable interest rate). No impact on equity or total comprehensive income of the Company was presented.

	Increase /	Impact on
	decrease by percentage	gross profit
	points	or loss
As at 31 December 2020
PLN	+0,5%	(18,486)
EUR	+0,5%	(25,488)
USD	+0,5%	(695)
PLN	-0,5%	18,486
EUR	-0,5%	25,488
USD	-0,5%	695
As at 31 December 2019
PLN	+0,5%	(8,717)
EUR	+0,5%	(31,948)
USD	+0,5%	(266)
PLN	-0,5%	8,717
EUR	-0,5%	31,948
USD	-0,5%	266
As at 1 January 2019
PLN	+0,5%	(393)
EUR	+0,5%	(4,698)
USD	+0,5%	(187)
PLN	-0,5%	393
EUR	-0,5%	4,698
USD	-0,5%	187

30.7. Credit risk management

Credit risk is the risk that a contracting party will default on its contractual obligations, resulting in the Company's financial losses. The Company enters into transactions only with creditworthy contracting parties. If necessary, the risk of financial losses due to default is reduced by collateral. While assessing its major customers, the Company also uses other publicly available financial information and internal transaction data. The Company's exposure to counterparty credit risk is monitored on an ongoing basis and the aggregate value of concluded transactions is distributed over approved contracting parties.

Trade receivables comprise amounts due from large, reliable and key customers operating in different geographies. Regular credit analyses are also performed considering the status of receivables.

Excludnig the Company's major customers (information on revenue has been presented in Note 6.5), the Company is not exposed to considerable credit risk with respect to a single counterparty. Each of these customers is an international company with a stable financial position, which considerably reduces credit risk. The concentration of credit risk with respect to other customers does not exceed 10% of gross monetary assets during the year.

Credit risk related to liquid assets is limited as the Company's contracting parties are banks with a high credit rating assigned by international rating agencies. Data on receivables as at the balance sheet date can be found in Note 22 and data on the contracted asset are provided in Note 5.3.

The credit risk related to cash is limited as the Company's counterparties are banks with high credit ratings awarded by international rating agencies.

30.8. Liquidity risk management

The ultimate responsibility for liquidity risk management rests with the Management Board, which has developed a suitable management system for short-, medium- and long-term funding and liquidity requirements. The Company's liquidity management consists in maintaining the reserve capital at an appropriate level, keeping stand-by lines of credit, ongoing monitoring of projected and actual cash flows and alignment of the maturity of financial assets with that of financial liabilities.

	As at 31/12/2020	As at 31/12/2019	As at 01/01/2019
Financial assets (+)	164,602,349	81,588,980	136,996,836
Receivables (including trade receivables of disposal groups)	3,414,646	6,493,303	27,085,763
Receivables from share buyback	-	2,988,750	-
Cash	136,218,238	72,106,927	94,858,075
Other financial assets	24,969,465	-	15,052,998
Financial liabilities (-)	(18,249,987)	(27,629,909)	(43,031,759)
Interest bearing credit facilities and loans	(2,362,057)	(3,185,808)	(4,053,135)
Finance lease liabilities	(5,042,549)	(6,030,953)	(22,070,778)
Trade liabilities	(6,260,821)	(13,350,186)	(16,690,287)
Investment liabilities	(4,584,560)	(5,062,962)	(217,559)
Exposure to liquidity risk	146,352,362	53,959,071	93,965,077

As at the balance sheet date, December 31, 2020, the company's financial liabilities were within the following maturity ranges:

	Current:				Non-current:
Type of liability	Not overdue as at 31/12/2020	within 3 months	3-12 months	Total current liabilities	1-5 years	over 5 years	Total non-current liabilities	Liabilities – carrying amount
Interest bearing credit facilities and loans	-	202,455	607,365	809,820	1,552,237	-	1,552,237	2,362,057
Finance lease liabilities	-	661,991	1,605,969	2,267,960	2,774,589	-	2,774,589	5,042,549
Trade liabilities	9,611,123	1,185,089	49,169	10,845,381	-	-	-	10,845,381
Total	9,611,123	2,049,535	2,262,503	13,923,161	4,326,826	-	4,326,826	18,249,987

As at the balance sheet date, December 31, 2019, the company's financial liabilities were within the following maturity ranges:

	Current:				Non-current:
Type of liability	Not overdue as at 31/12/2019	within 3 months	3-12 months	Total current liabilities	1-5 years	over 5 years	Total non-current liabilities	Liabilities – carrying amount
Interest bearing credit facilities and loans	-	216,385	607,365	823,750	2,362,058	-	2,362,058	3,185,808
Finance lease liabilities	-	631,694	1,843,274	2,474,968	3,555,985	-	3,555,985	6,030,953
Trade liabilities	14,170,996	2,319,828	1,922,324	18,413,148	-	-	-	18,413,148
Total	14,170,996	3,167,907	4,372,963	21,711,866	5,918,043	-	5,918,043	27,629,909

As at the balance sheet date, January 1, 2019, the company's financial liabilities were within the following maturity ranges:

	Current:				Non-current:
Type of liability	Not overdue as at 01/01/2019	within 3 months	3-12 months	Total current liabilities	1-5 years	over 5 years	Total non-current liabilities	Liabilities – carrying amount
Interest bearing credit facilities and loans	-	273,892	607,365	881,257	3,171,878	-	3,171,878	4,053,135
Finance lease liabilities	-	1,399,292	4,197,877	5,597,169	16,473,609	-	16,473,609	22,070,778
Trade liabilities	12,261,890	4,426,835	219,121	16,907,846	-	-	-	16,907,846
Total	12,261,890	6,100,019	5,024,363	23,386,272	19,645,487	-	19,645,487	43,031,759

30.8.1 Available external sources of funding

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Collateralized overdraft facilities:
Amount used	4,645	13,930	71,437
Amount available	395,355	386,070	328,563
	400,000	400,000	400,000

31. Accrued costs

Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
PLN	PLN	PLN
1,185,204	741,595	1,078,966
3,458,026	1,641,000	1,900,000
4,643,230	2,382,595	2,978,966
4,643,230	2,382,595	2,978,966
-	-	-
4,643,230	2,382,595	2,978,966

32. Deferred income

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Payments from Partners (i) revenues recognized in accordance with IFRS 15	-	-	1,169,725
Government subsidies (ii) revenues recognized in accordance with IAS 20	42,061,588	23,482,263	13,515,386
	42,061,588	23,482,263	14,685,111
Short-term	14,558,963	2,298,553	4,322,365
Long-term	27,502,625	21,183,710	10,362,746
	42,061,588	23,482,263	14,685,111
Government subsidies (ii) revenues recognized in accordance with IAS 20
Infrastructure subsidies, including:	27,791,084	20,846,481	11,048,154
- Short-term	2,968,894	1,428,184	1,428,184
Research subsidies, including:	14,270,504	2,635,782	2,467,232
- Short-term	11,590,069	870,369	1,724,456
	42,061,588	23,482,263	13,515,386

(i) Payments from partners include advance payments from contractors to cover part of the costs associated with the services performed.

(ii) Government subsidies include payments received resulting from subsidy contracts signed.

33. Related party transactions

33.1. Commercial transactions

In the financial year, the Company concluded the following commercial transactions with related parties (including in person):

	Sales of goods and services		Purchases of goods and services
Period ended 31/12/2020	Year ended 31/12/2019	Period ended 31/12/2020	Year ended 31/12/2019
PLN	PLN	PLN	PLN
1,498,501	535,346	3,503,923	1,182,205
444	4,217,393	1,948,846	10,079,900
-	220,575	-	9,658
917	2,542,703	-	-
334,207	3,153,045	-	-
-	-	20,841	9,415
1,834,069	10,669,062	5,473,610	11,281,178

Additionally, in September 2020, Selvita S.A. repaid to the Issuer the liability resulting from the redemption of '0' shares resulting from the spin-off of ZCP in the amount of PLN 2,988,750 (Note 22).

Balances at the end of the reporting period:

		Amounts due from related parties			Amounts due to related parties
	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN	PLN	PLN	PLN
Selvita S.A.	1,568,851	4,022,579	-	803,959	1,509,006	-
Selvita Services Sp. z o.o.	546	150	2,662,408	495,675	374,714	4,209,688
Ardigen S.A.	-	-	198,839	-	-	14,307
Selvita Inc.	-	372	208,870	-	-	1,099
Selvita Ltd.	350,794	-	345,515	-	-	-
	1,920,191	4,023,101	3,415,632	1,299,634	1,883,720	4,225,094

Transactions with related entities were made using market prices.

33.2. Loans to related parties

None.

33.3. Loans from related parties

None.

33.4. Executive compensation

Compensation of members of the Management Board and other executives in the financial year:

	Period ended	Period ended
	31/12/2020	31/12/2019
	PLN	PLN
Management Board	2,971,876	1,722,930
Paweł Tadeusz Przewięźlikowski	582,088	524,126
Krzysztof Daniel Brzózka	780,673	591,654
Setareh Gharayagh Shamsili	1,559,081	607,150
Kamil Sitarz	50,034	-
Supervisory Board	1,025,666	296,980
Piotr Romanowski	142,847	68,027
Tadeusz Wesołowski	140,745	64,718
Rafał Piotr Chwast	142,847	62,087
Axel Glasmacher	140,745	33,830
Colin Goddard	140,745	33,830
Jarl Jungnelius	141,403	34,488
Thomas Turalski	176,334	-
	3,997,542	2,019,910

33.5. Loans and similar benefits granted to members of management, supervisory and administration bodies of the Company

None.

34. Business combinations

None.

35. Cash and cash equivalents

For purposes of preparation of the statement of cash flows, cash and cash equivalents consist of cash in hand and cash at bank, including open overdraft facilities. Cash and cash equivalents at the end of the financial year, presented in the statement of cash flows, can be reconciled with the balance sheet items in the following manner:

At the balance sheet date, funds collected on bank accounts are not adjusted due to risk of impairment as these funds are accumulated in banks belonging to large capital groups with an established market position.

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN

Cash in hand and at bank	93,068,338	25,937,115	22,757,560
Overdraft facilities	-	-	-
	93,068,338	25,937,115	22,757,560

Cash and cash equivalents - bank deposits	43,149,900	46,169,812	72,100,515
	136,218,238	72,106,927	94,858,075

36. Average headcount in the Company

		Year ended 31/12/2020 Year ended 31/12/2019
White collar employees	162	299
Blue collar employees	-	-
Total headcount	162	299

37. Capital commitments

	Balance as at	Balance as at	Balance as at
	31/12/2020	31/12/2019	01/01/2019
	PLN	PLN	PLN
Commitments to purchase property, plant and equipment	7,241,227	4,893,907	8,468,496

Obligations to purchase property, plant and equipment result from subsidy agreements signed by the Company for the creation and increase of the potential of laboratories.

38. Contingent liabilities and assets

38.1. Contingent liabilities

In the periods covered by the financial statements, the Company incurred contingent liabilities necessary to receive a subsidy and a loan. Contingent liabilities include:

promissory note liabilities - covering the amount of co-financing granted with interest in the amount specified as for tax arrears calculated from the date of transferring funds for the account to the date of return. In the period covered by the report, PLN 45,784,270, was credited to the bank accounts for co-financing. As at the balance sheet date, 31/12/2020, the sum of cash received under the subsidy is PLN 165,690,744.

On August 7, 2017, the Management Board of Ryvu Therapeutics S.A. (formerly Selvity S.A.) has concluded an agreement with Leukemia & Lymphoma Society regarding cooperation in further research of the preclinical phase and the first clinical phase of the SEL120 molecule. Pursuant to the provisions of the Agreement, LLS undertook to provide the Company with financial support of up to USD 3.25 million. In exchange for the financial support provided, LLS will be entitled, after successful development of SEL120 and leading to the commencement of clinical phase III, to receive payments for obtaining milestones, and after commercialization of SEL120 or to the market by the Company also to royalties. The total value of payments for LLS will not exceed seven times the grant awarded. From the date of signing the agreement until 31/12/2020, the Company received in total USD 1.75 million. As at 31/12/2020, the Company does not recognize an obligation due to funds received from LLS due to the early stage of project implementation and the related low probability of repayment.

38.2. Contingent assets

There was no issue in the periods covered by the financial statements.

39. Significant events of the reporting period

Coronavirus (COVID-19)

In the reporting period, the Issuer noted the negative impact of the above-mentioned events on the progress of the CLI120-001 clinical trial conducted by it. This is related to the general global trend that Phase I "First in Human (FIH)" dose escalation clinical trials have been particularly hard hit during the pandemic period. It seems that these negative effects were more severe in research centers located in the United States. Due to the Covid-19 pandemic, all SEL120 / RVU120 / RVU120 clinical centers introduced additional safety measures and risk management processes that strongly influenced the participation of patients in clinical trials. This also applies to patients with relapsed or refractory AML, who are often immunocompromised. Also, many patients have independently chosen to limit their contact with various healthcare settings to minimize the possibility of exposure to Covid-19. As a result, registration in some centers was temporarily suspended and visibly slowed down in others. Currently, the delays in the planned recruitment of patients for the studies due to COVID-19 are about 6 months. As a consequence, the Company decided to postpone the planned schedule of the first results of the study from December 2020 to the second half of 2021. An additional new risk related to the pandemic of recruiting patients to oncological clinical trials is the launch of a worldwide vaccination campaign against COVID-19. Merely receiving vaccination or waiting for a patient to receive vaccination in the near future may have a negative impact on his or her eligibility for clinical trials.

During reported period, the pandemic affected the progress of the Issuer's clinical trials due to the fact that they are conducted in the centers located in the United States. Due to the onset of Covid19 pandemic all SEL120 clinical sites have introduced additional safety measures and risk management processes which have strongly impacted the possibilities for patients to participate in clinical studies. This applies particularly to AML patients who are frequently immunocompromised. Also many patients themselves decided to limit their contacts with various healthcare facilities to minimize the possibility of Covid-19 exposure. In effect enrollment at some sites has been temporarily suspended and in other sites visible slowed-down. The current delay in the planned study enrollment is approximately 6 months. As a consequence Ryvu has decided to move the anticipated timelines for the first results of the study from.

Due to the continuing pandemic, the Issuer is not able to predict any further delays in the ongoing clinical trials as at the date of publication of this report, but has taken steps to minimize the risk of their negative impact on the Company's operations. In the original plan of the study Ryvu intended to open the enrollment in the dose escalation part at three additional sites in the US (nine sites in total). Because of the pandemic situation in the US. Ryvu management has decided to start the European arm of the study earlier than originally expected and include additional sites in Poland and other European countries. The first in Europe Clinical Trial Application (CTA) was submitted on August 11, 2020. At the beginning of January 2021 Ryvu Polish Office for Registration of Medicinal Products, Medical Devices and Biocidal Products, and the respective Central Ethics Committee approved Ryvus CTA to commence SEL120 clinical trial in clinical centres in Poland.

As far as outsourced research and development services are concerned, in Q3 2020 there were temporary problems with outsourcing work to laboratories located mainly in Europe.

The Issuer's research and development laboratories worked during reporting period with decreased capacity. The decrease in their capacity was associated with employee absenteeism due to quarantine, the fact that some foreigners could not enter Poland and the fact that some employees had to stay home with their children, as well as due to the relocation of employees to the new R&D Center. A significant proportion of the Issuer's office staff worked remotely, which could also have had an adverse effect on the speed of carrying out the project. The research and development work was additionally slowed down by the procedures implemented to prevent infections, e.g. dividing teams into smaller ones, limiting personal contact, decontamination of laboratories, and shift work.

The Issuer also identifies foreign exchange risk. 90% of the Issuer's cash is kept in PLN. The grants obtained are also denominated in PLN, whereas the costs of clinical trials and external research and development services are mostly denominated in foreign currencies. This risk is partly mitigated by guaranteed and expected revenues from the commercialization of projects, which are denominated in foreign currencies. The Issuer also identified risks associated with delays in administrative processes relating to granting and settling grants or VAT reimbursement and regulatory processes concerning clinical trials.

The Management Board of the Company analyzes the situation related to the spread of the pandemic on an ongoing basis and implements new solutions to limit it on an ongoing basis, including, in particular, increased sanitary regime, disinfection of laboratories and the entire facility of the Research and Development Center, by using masks, temperature measurements and voluntary testing of the employees for Covid-19. Additionally, in connection with the launch of the national vaccination program against COVID-19, Ryvu is monitoring the possibility and possible planned term of covering Ryvu's employees with the above-mentioned program.

The Company's Management Board is analysing the Issuer's situation on an ongoing basis. New circumstances, if any, having a significant effect on the Issuer's financial results and business position, will be communicated promptly in the individual current reports.

40. Notes to the cash flow statement

Explanation of the reasons for significant differences between changes in certain items in the balance sheet and changes in the same items disclosed in the cash flow statement:

Item	Year ended 31/12/2020	Year ended 31/12/2019
	PLN	PLN
Change in trade and other receivables:	3,743,995	11,672,675
- change in trade and other receivables due to split	-	(8,095,687)
- change in receivables due to payment for shares	(2,988,750)	-
- change in trade and other receivables resulting from the balance sheet	6,732,745	19,768,362
Change in inventory:	(89,550)	(682,736)
- change in inventory due to split	-	(698,582)
- change in inventory resulting from the balance sheet	(89,550)	15,846
Change in liabilities, except for loans and borrowings:	(11,060,893)	(1,088,984)
- change in liabilities due to split	-	(13,200,999)
- change in liabilities resulting from the balance sheet	(11,060,893)	(2,318,796)
- change in liabilities related to purchase of fixed asssets	-	(11,971,187)
Change in deferred income:	20,839,960	14,660,445
- change in deferred income due to split	-	5,863,293
- change in deferred income resulting from the balance sheet	20,839,960	8,797,152
Change in provisions:	898,325	(160,890)
- change in provisions due to split	-	(391,916)
- change in provisions resulting from the balance sheet	898,325	231,026
Change in other assets:	158,799	(4,378,395)
- change in other assets due to split	-	(6,540,665)
- change in the balance of other assets resulting from the sale of financial assets	-	-
- change in other assets resulting from the balance sheet	158,799	2,162,270
Change in loans:	(819,106)	(881,258)
- change in long-term loans due to split	-	-
- change in short-term loans due to split	-	(13,931)
- change in long-term loans resulting from the balance sheet	(809,821)	(809,820)
- change in in short-term loans resulting from the balance sheet	(9,285)	(57,507)

41. Remuneration of the statutory auditor or audit company

Item	Balance as at 31/12/2020	Balance as at 31/12/2019	Balance as at 01/01/2019
	PLN	PLN	PLN
Obligatory audit of the annual financial statements	105,000	247,000	75,000
Other advisory services	90,000	-	40,000
Tax advisory services	-	-	-
Other	-	-	-
Total remuneration	195,000	247,000	115,000

42. Revenues and costs of R&D own services

Item	Balance as at 31/12/2020	Balance as at 31/12/2019	change year over year
	PLN	PLN	PLN
Net revenues from the sale of research and development services	15,414,308	11,331,475	4,319,049
Expenses for conducting research and development works [PLN]	72,977,550	67,625,431	6,551,058
Employment in positions related to research and development works	162	162	-

43. Major events pertaining to prior years and presented in the financial statements for the current year

None.

44. Major events pertaining to prior years and presented in the financial statements for the current year

None.

45. Major events after the end of the reporting period which have not been presented in the financial statements

None.

46. Subsequent events

Recommendation for co-financing by the National Center for Research and Development of the Issuer's project concerning a clinical trial of the SEL120 / RVU120 (RVU120) molecule in solid tumors

On January 18, 2021, the Issuer was informed about the placement of the Issuer's project entitled "Clinical development of an innovative drug candidate in solid cancer therapy" ("Project") on the list of projects selected for funding under the Smart Growth Operational Program 2014-2020, measure 1.1 / sub-measure 1.1.1 "Fast Track".

47. Approval of the financial statements

The financial statements were approved by the Company's management board on March 12, 2021.

Prepared by: Elżbieta Kokoć

Signatures of members of the Management Board:

Paweł Tadeusz Przewięźlikowski - President of the Board

Krzysztof Daniel Brzózka - V-ce President

Setareh Gharayagh Shamsili - V-ce President

Kamil Sebastian Sitarz - Member of the Board

Cracow, 12 March 2021 r.

CONTACT

RYVU THERAPEUTICS

Leona Henryka Sternbacha 2

30-394 Krakow, Poland

Tel: +48 12 314 02 00

GENERAL INQUIRIES

[email protected]

AI assistant

RYVU Therapeutics S.A. — Audit Report / Information 2020

5798_rns_2021-03-16_e3638408-2046-45fa-a9ea-eb84e168ad3c.pdf

FINANCIAL STATEMENTS RYVU THERAPEUTICS S.A.

Notes to the Interim Financial Statements

Page

STATEMENT OF COMPREHENSIVE INCOME FOR THE PERIOD FROM 1 JANUARY 2020 TO 31 DECEMBER 2020

STATEMENT OF FINANCIAL POSITION PREPARED AS AT 31 DECEMBER 2020

STATEMENT OF CHANGES IN EQUITY FOR THE REPORTING PERIOD ENDED 31 DECEMBER 2020

STATEMENT OF CASH FLOWS

FOR THE PERIOD FROM 1 JANUARY 2020 TO 31 DECEMBER 2020

NOTES TO THE FINANCIAL STATEMENTS PREPARED AS AT 31 DECEMBER 2020

1. General information

1.1. The company

1.2. Going concern assumption

1.3. Functional and reporting currency

2. International Financial Reporting Standards

2.1. Statement of compliance

2.1.1. Reporting period and scope

Status of IFRS endorsement by the EU

2.2. The following standards and interpretations have been published by the International Accounting Standards Board, but they do not apply to these financial statements (i.e. for 12-months financial statements ended December 31, 2020)

3. Summary of significant accounting policies

3.1. Going concern

3.2. Basis of preparation

3.3. Investments in associates

3.5. Non-current assets held for sale

3.6. Revenue recognition

3.6.1. Grants

3.6.2. Sales of goods and services

3.7. Interest and dividend income

3.8. Leases Assets due to the right of use The Company as a lessee

Lease liabilities

Short-term leasing and leasing of low-value assets

3.9. Foreign currencies

3.10. Borrowing costs

3.11. Costs of employee benefits and contract termination

3.12. Taxes

3.12.1. Current tax

3.12.2. Deferred tax

Uncertainty associated with the recognition of income tax

3.12.3. Current and deferred tax for the period

3.13. Property, plant and equipment

3.14. Intangible assets

3.14.1. Intangible assets

3.14.2. Intangible assets developed internally – R&D cost

3.14.3. Derecognition of intangible assets

3.15. Impairment of property, plant and equipment and intangible assets, except goodwill

3.16. Inventories

3.17. Provisions

3.17.1. Onerous contracts

3.17.2. Restructuring

3.18. Cash and cash equivalents

3.19. Financial instruments

3.19.1. Classification and initial recognition of financial instruments

Cessation of recognition

Financial assets measured at amortized cost

Financial assets at fair value through other comprehensive income

Financial assets at fair value through other comprehensive income

Financial assets at fair value through profit or loss

Trade and other liabilities

Interest-bearing bank loans, loans and debt securities

3.19.2. Impairment of financial instruments

3.19.3. Hedge accounting

4. Significant accounting judgements and estimates

4.1. Professional judgment in accounting

Recognition of grants

Recognition of patents

Leasing - the Company as a lessee

Lease period for contracts with extension options

Lease period for contracts of unlimited duration

Lessee's marginal interest rate

4.2. Uncertainty of estimates

4.2.1. Provisions for bonuses

4.2.2. Useful lives of property, plant and equipment

4.2.3. Accounting for long-term contracts using the estimated stage-of-completion method

4.2.4. Deferred tax asset

4.2.5. Tax settlements

4.2.6. Fair value of financial instruments

4.2.7. Impairment of trade receivables and contract assets

4.2.8. Revenue recognition

RYVU Therapeutics S.A. Audit Report / Information 2020