Rua Bioscience Limited — Share Issue/Capital Change 2021

Oct 12, 2021

MARKET ANNOUNCEMENT

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12[th] October 2021

Notice of issue of ordinary shares under Rua Bioscience Limited’s share option plan

This notice is given under NZX Listing Rules 3.13.1 and 3.15.2 and relates to the issue of fully paid ordinary shares in Rua Bioscience Limited (the Company ) upon exercise of vested options issued and granted under the share option plan of the Company (the Share Option Plan ).

Under the Share Option Plan, one vested option will convert into 5.882 ordinary shares upon exercise.

This notice provides details of the issue of 1,417,856 ordinary shares in the Company upon exercise of options granted to selected eligible employees of the Company pursuant to the rules of the Share Option Plan.

Section 1: Issuer information

Section 1: Issuer information	Section 1: Issuer information
Name of issuer	Rua Bioscience Limited
NZX ticker code	RUA
Class of Security	Ordinary Shares
ISIN	NZRUAE0004S1
Section 2: Capital change details
Number issued	1,417,856
Issue price per Security	No cash consideration is payablefor the issue of the OrdinaryShares
Nature of the payment (for example, cash or other consideration)	Not applicable
Amount paid up	Fully paid
Percentage of total class of Securities issued	1.01% (of the total number ofOrdinary Shares in Rua on issueimmediately prior to completionof the issue)
Reason for issue	Issue of ordinary shares uponexercise of options pursuant tothe Share Option Plan.
Total number of securities of the Class in existence after the issue	141,739,267 Ordinary Sharesfollowing the issue
Specific authority for the issue	Resolution of Directors’ upongranting of options andsubsequentlyto account for a

	“share split”. The Shares wereissued in accordance with ListingRule 4.6.
Terms of the issue	Terms of the Share Option Plan.The issued shares will rankequally in all respects with theother fully paid ordinary shareson issue.
Date of issue	12thOctober 2021
Details of interest of dividend conditions attaching to securitiesconverted and allotted on conversion	Nil
Number of securities of the same class still to be converted	Nil
Section 3: Authority for this announcement and contact person
Name of person authorised to make this announcement	Hamish White, Chief FinancialOfficer of Rua Bioscience Limited
Contact person for this announcement	Kerry Donovan
Contact phone number	+64 21 128 7689
Contact email address	Kerry.donovan@ruabio.com
Date of release through MAP	12thOctober 2021