Rua Bioscience Limited — Capital/Financing Update 2025

Nov 20, 2025

==> picture [101 x 28] intentionally omitted <==

UPDATED QUOTATION NOTICE: NZX MAIN BOARD RUA BIOSCIENCE LIMITED (“RUARB”) RIGHTS

Issuer: Rua Bioscience Limited (“RUA”) Ticker Code: RUARB ISIN: NZRUAE0006S6 Details of Issue: A pro-rata renounceable rights issue of 1 new share for every 3 existing shares held on the Record Date. Ratio (New: Existing): 1 : 3 Exercise Price: NZ$0.025 per new share Reference Price: Calculated as head share price prior to quotation minus the Exercise Price Issue Price Payable: In full on application Registrar: Computershare Investor Services Limited (“RMLT”) Settlement Status: NZCDC Settlement System Key Dates Ex Rights Date: Friday, 7 November 2025 Rights Commence Trading: Friday, 7 November 2025 Record Date: 5pm, Monday, 10 November 2025 Letters of Entitlement sent to Tuesday, 11 November 2025 Shareholders: Offer Opens: Tuesday, 11 November 2025 Rights Quotation Ceases: Monday, 8 December 2025 Offer Closes: Friday, 12 December 2025 Allotment and commencement of Thursday, 18 December 2025 trading of New Shares (retail offer):

==> picture [137 x 65] intentionally omitted <==

Mark Peterson Chief Executive Officer NZX Limited

20 November 2025