Royalty Pharma plc — Director's Dealing 2025

May 20, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Royalty Pharma plc (RPRX)
CIK: 0001802768
Period of Report: 2025-05-16

Reporting Person: Legorreta Pablo G. (Director, CEO, Chairman of the Board)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-05-16	Class A Ordinary Shares	J	530348	—	Acquired	882495	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-05-16	Class E Ordinary Shares	$0	A	13356742	Acquired		Class A Ordinary Shares (13356742)	Indirect
2025-05-16	Option (Right to Buy)	$0	J	857138	Acquired		Class A Ordinary Shares (857138)	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Class A Ordinary Shares	460139	Indirect
Class A Ordinary Shares	123310	Indirect
Class A Ordinary Shares	118500	Indirect
Class A Ordinary Shares	1040410	Indirect
Class A Ordinary Shares	901590	Indirect
Class A Ordinary Shares	41306	Indirect
Class A Ordinary Shares	6930	Indirect
Class A Ordinary Shares	292190	Indirect
Class A Ordinary Shares	10000	Indirect
Class A Ordinary Shares	10000	Indirect
Class A Ordinary Shares	600000	Indirect

Footnotes

F1: Represents the transfer to the Reporting Person by the RP Management Equity Incentive Plan Trust of Class A Ordinary Shares for no consideration.

F2: Reflects the exempt acquisition by the Reporting Person pursuant to Rule 16b-3 of Class E ordinary shares ("Class E Shares") of Royalty Pharma Holdings Ltd ("RPH") in connection with the consummation of the transactions contemplated by the Membership Interests Purchase Agreement, dated as of January 10, 2025 (as may be amended from time to time, the "Purchase Agreement") between RPH, Royalty Pharma, LLC, RP Management, LLC, the Issuer and certain other parties thereto.

F3: Each Class E share will vest in installments over a 5-year period. Once vested, the Class E Shares may be converted at any time into an equivalent number of Class B ordinary shares of RPH ("Class B Shares") on a one-for-one basis, and there is no expiration date for such conversion. Each Class B Share may be converted at any time into an equivalent number of Class A ordinary shares of the Issuer on a one-for-one basis, and there is no expiration date for such conversion.

F4: Represents the Reporting Person's right to acquire certain Class E Shares held by other employees of the Issuer and its subsidiaries in the event such Class E Shares are forfeited by such employee.