RHYTHM PHARMACEUTICALS, INC. — Director's Dealing 2017

Oct 10, 2017

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: RHYTHM PHARMACEUTICALS, INC. (RYTM)
CIK: 0001649904
Period of Report: 2017-10-10

Reporting Person: Ipsen, S.A. (10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2017-10-10	Common Stock	C	45831	—	Acquired	645161	Indirect
2017-10-10	Common Stock	C	167938	—	Acquired	813099	Indirect
2017-10-10	Common Stock	P	20000	$17.00	Acquired	833099	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2017-10-10	Series A-1 Junior Preferred Stock	$	C	45831	Disposed		Common Stock (45831)	Indirect
2017-10-10	Series A Convertible Preferred Stock	$	C	167938	Disposed		Common Stock (167938)	Indirect

Footnotes

F1: In connection with the closing of the Issuer's initial public offering, each share of the Issuer's series A convertible preferred stock (the "Series A Preferred") and series A-1 junior preferred stock (the "Series A-1 Preferred") converted into the Issuer's common stock on a 9.17-for-one basis without payment or consideration. The Series A Preferred and the Series A-1 Preferred had no expiration date.

F2: Reflects the number of shares of Series A Preferred and Series A-1 Preferred, as applicable, held by the Reporting Person on an as-converted to common stock basis.