RHYTHM BIOSCIENCES LIMITED — Share Issue/Capital Change 2021

Sep 8, 2021

Announcement Summary

Entity name

RHYTHM BIOSCIENCES LIMITED

Announcement Type

New announcement

Date of this announcement

Thursday September 09, 2021

The +securities to be quoted are:

+Securities issued as part of a transaction or transactions previously announced to the market in an Appendix 3B

Total number of +securities to be quoted

ASX +securitycode	Security description	Number of +securities tobe quoted	Issue date
RHY	ORDINARY FULLY PAID	5,054,270	09/09/2021

Refer to next page for full details of the announcement

Part 1 - Entity and announcement details

1.1 Name of entity

RHYTHM BIOSCIENCES LIMITED

We (the entity named above) apply for +quotation of the following +securities and agree to the matters set out in Appendix 2A of the ASX Listing Rules.

1.2 Registered number type ACN

Registration number 619459335

1.3 ASX issuer code RHY

1.4 The announcement is

New announcement

1.5 Date of this announcement

9/9/2021

Part 2 - Type of Issue

2.1 The +securities to be quoted are:

+Securities issued as part of a transaction or transactions previously announced to the market in an Appendix 3B

Previous Appendix 3B details:

Announcement Date andTime	Announcement Title	Selected Appendix 3B to submit quotationrequest
30-Jul-2021 11:18	Update - Update - Proposed issue ofsecurities - RHY	A standard +pro rata issue (non-renounceable)

2.3a.2 Are there any further issues of +securities yet to take place to complete the transaction(s) referred to in the Appendix 3B?

Yes

2.3a.3 Please provide details of the further issues of +securities yet to take place to complete the transaction(s) referred to in the Appendix 3B

Free attaching options under the rights issue offer, as set out in the prospectus dated 30 July 2021, will be issued under a Appendix 3G to be lodged contemporaneously with the issue of the shares under this Appendix 2A.

Part 3A - number and type of +securities to be quoted where issue has previously been notified to ASX in an Appendix 3B

Corporate Action Component Detail

ASX +security code and description

RHY : ORDINARY FULLY PAID

Issue date

9/9/2021

Distribution Schedule

Provide a distribution schedule for the new +securities according to the categories set out in the left hand column including the number of recipients and the total percentage of the new +securities held by the recipients in each category.

Number of +securities held	Number of holders	Total percentage of +securities heldFor example, to enter a value of 50%please input as 50.00
1 - 1,000		%
1,001 - 5,000		%
5,001 - 10,000		%
10,001 - 100,000		%
100,001 and over		%

Issue details

Number of +securities to be quoted

5,054,270

Issue currency

Issue price or consideration per +security

AUD - Australian Dollar

AUD 0.85000000

Any other information the entity wishes to provide about the +securities to be quoted

Part 4 - Issued capital following quotation

Following the quotation of the +securities the subject of this application, the issued capital of the entity will

comprise:

(A discrepancy in these figures compared to your own may be due to a matter of timing if there is more than one application for quotation/issuance currently with ASX for processing.)

4.1 Quoted +securities (total number of each +class of +securities quoted on ASX following the +quotation of the +securities subject of this application)

ASX +security code and description	Total number of+securities on issue
RHY : ORDINARY FULLY PAID	207,300,081

4.2 Unquoted +securities (total number of each +class of +securities issued but not quoted on ASX)

ASX +security code and description	Total number of+securities on issue
RHYAK : OPTION EXPIRING 31-AUG-2022 DEFERRED	2,527,135
RHYAL : OPTION EXPIRING 31-JUL-2024 DEFERRED	2,527,135
RHYAH : OPTION EXPIRING 14-SEP-2023 EX 20C	7,400,000
RHYAI : OPTION EXPIRING 31-JUL-2024 EX $1.80	2,895,000