RHYTHM BIOSCIENCES LIMITED — Capital/Financing Update 2021

Sep 12, 2021

Announcement Summary

Entity name

RHYTHM BIOSCIENCES LIMITED

Date of this announcement

Monday September 13, 2021

The +securities the subject of this notification are:

+Securities issued as part of a transaction or transactions previously announced to the market in an Appendix 3B that are not quoted, and are not intended to be quoted, on ASX

Total number of +securities to be issued/transferred

ASX +securitycode	Security description	Total number of+securities to beissued/transferred	Issue date
RHYAK	OPTION EXPIRING 31-AUG-2022 EX $1.20	750,000	13/09/2021
RHYAL	OPTION EXPIRING 31-JUL-2024 $1.80	750,000	13/09/2021

Refer to next page for full details of the announcement

Part 1 - Entity and announcement details

1.1 Name of entity

RHYTHM BIOSCIENCES LIMITED

We (the entity named above) give notice of the issue, conversion or payment up of the following unquoted +securities.

1.2 Registered number type ABN

Registration number

59619459335

1.3 ASX issuer code RHY

1.4 The announcement is New announcement

1.5 Date of this announcement

13/9/2021

Part 2 - Issue details

2.1 The +securities the subject of this notification are:

+Securities issued as part of a transaction or transactions previously announced to the market in an Appendix 3B that are not quoted, and are not intended to be quoted, on ASX

Previous Appendix 3B details:

Announcement Date andTime	Announcement Title	Selected Appendix 3B to submit quotationrequest
07-Sep-2021 13:13	New - Proposed issue of securities -RHY	A placement or other type of issue

2.3a.2 Are there any further issues of +securities yet to take place to complete the transaction(s) referred to in the Appendix 3B? No

Part 3A - number and type of +securities the subject of this notification (existing class or new class) where issue has previously been

notified to ASX in an Appendix 3B

Placement Details

ASX +security code and description RHYAK : OPTION EXPIRING 31-AUG-2022 EX $1.20

Date the +securities the subject of this notification were issued

13/9/2021

Any other information the entity wishes to provide about the +securities the subject of this notification

Issue details

Number of +securities 750,000

Were the +securities issued for a cash consideration? No

Please describe the consideration being provided for the +securities

Free attaching to the placement shares.

ASX +security code and description

RHYAL : OPTION EXPIRING 31-JUL-2024 $1.80

Date the +securities the subject of this notification were issued

13/9/2021

Equity Securities

Any other information the entity wishes to provide about the +securities the subject of this notification

Issue details

Number of +securities

750,000

Were the +securities issued for a cash consideration?

No

Please describe the consideration being provided for the +securities

Free attaching to the placement shares.

Part 4 - +Securities on issue

Following the issue, conversion or payment up of the +securities the subject of this application, the +securities of the entity will comprise: (A discrepancy in these figures compared to your own may be due to a matter of timing if there is more than one application for quotation/issuance currently with ASX for processing.) 4.1 Quoted +Securities (Total number of each +class of +securities quoted) ASX +security code and description Total number of +securities on issue RHY : ORDINARY FULLY PAID 207,300,081

4.2 Unquoted +Securities (Total number of each +class of +securities issued but not quoted on ASX)

ASX +security code and description	Total number of+securities on issue
RHYAK : OPTION EXPIRING 31-AUG-2022 EX $1.20	3,276,808
RHYAL : OPTION EXPIRING 31-JUL-2024 $1.80	3,276,808
RHYAH : OPTION EXPIRING 14-SEP-2023 EX 20C	7,400,000
RHYAI : OPTION EXPIRING 31-JUL-2024 EX $1.80	2,895,000