REPLIGEN CORP — Director's Dealing 2025

Nov 14, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: REPLIGEN CORP (RGEN)
CIK: 0000730272
Period of Report: 2025-11-13

Reporting Person: Hunt Anthony (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-11-13	Common Stock	S	1784	$151.01	Disposed	98959	Direct
2025-11-13	Common Stock	S	2100	$152.17	Disposed	96859	Direct
2025-11-13	Common Stock	S	2923	$153.14	Disposed	93936	Direct
2025-11-13	Common Stock	S	2500	$154.32	Disposed	91436	Direct
2025-11-13	Common Stock	S	3000	$155.45	Disposed	88436	Direct
2025-11-13	Common Stock	S	5737	$156.22	Disposed	82699	Direct
2025-11-13	Common Stock	S	1956	$157.11	Disposed	80743	Direct
2025-11-13	Common Stock	M	2952	$33.87	Acquired	83695	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-11-13	Stock Option (Right to Buy)	$33.87	M	2952	Acquired	2028-02-29	Common Stock (2952)	Direct

Footnotes

F1: $151.01 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $150.53 to $151.23, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F2: $152.17 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $151.57 to $152.45, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3: $153.14 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $152.64 to $153.62, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F4: $154.32 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $153.66 to $154.60, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F5: $155.45 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $154.78 to $155.78, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F6: $156.22 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $155.79 to $156.76, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F7: $157.11 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $156.90 to $157.55, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F8: 14,760 of the shares underlying this option have vested. The remaining shares vest as follows: 2,952 shares on March 1, 2026, and 2,952 shares on March 1, 2027.