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REPLIGEN CORP Director's Dealing 2013

May 15, 2013

30826_dirs_2013-05-15_0f4e22f6-e955-4b2e-8102-118079dbf01e.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: REPLIGEN CORP (RGEN)
CIK: 0000730272
Period of Report: 2013-05-13

Reporting Person: RYAN THOMAS F JR (Director)

Non-Derivative Transactions

Date Security Code Shares Price A/D Holdings After Ownership
2013-05-13 Common Stock M 39000 $7.56 Acquired 100038 Direct
2013-05-13 Common Stock S 39000 $9.0419 Disposed 61038 Direct
2013-05-13 Common Stock M 15000 $1.91 Acquired 76038 Direct
2013-05-13 Common Stock S 15000 $9.0419 Disposed 61038 Direct
2013-05-14 Common Stock M 15000 $3.38 Acquired 76038 Direct
2013-05-14 Common Stock S 15000 $8.9311 Disposed 61038 Direct
2013-05-14 Common Stock M 116 $3.10 Acquired 61154 Direct
2013-05-14 Common Stock S 116 $8.95 Disposed 61038 Direct
2013-05-14 Common Stock S 428 $9.05 Disposed 60610 Direct
2013-05-14 Common Stock S 1611 $9.07 Disposed 58999 Direct
2013-05-15 Common Stock M 14884 $3.10 Acquired 73883 Direct
2013-05-15 Common Stock S 14884 $8.9642 Disposed 58999 Direct

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2013-05-13 Stock Option (Right to Buy) $7.56 M 39000 Disposed 2013-09-10 Common Stock (39000) Direct
2013-05-13 Stock Option (Right to Buy) $1.91 M 15000 Disposed 2014-09-21 Common Stock (15000) Direct
2013-05-14 Stock Option (Right to Buy) $3.38 M 15000 Disposed 2015-09-15 Common Stock (15000) Direct
2013-05-14 Stock Option (Right to Buy) $3.10 M 116 Disposed 2016-09-15 Common Stock (116) Direct
2013-05-15 Stock Option (Right to Buy) $3.10 M 14884 Disposed 2016-09-15 Common Stock (14884) Direct

Footnotes

F1: $9.0419 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $9.03 to $9.06, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F2: $8.9311 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.90 to $8.96, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F3: $8.9642 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.95 to $9.01, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.