REPLIGEN CORP — Director's Dealing 2008

Feb 22, 2008

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: REPLIGEN CORP (RGEN)
CIK: 0000730272
Period of Report: 2008-02-20

Reporting Person: WITT DANIEL P (Vice President)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2008-02-20	Common Stock	J	44834	—	Disposed	44834	Indirect
2008-02-20	Common Stock	S	200	$5.81	Disposed	40300	Direct
2008-02-20	Common Stock	S	2000	$5.80	Disposed	38300	Direct

Footnotes

F1: Since the date of the reporting person's last ownership report, the reporting person transferred 44,834 shares of Repligen Corporation common stock to his wife pursuant to distribution of marital assets in divorce settlement.

F2: Sale pursuant to distribution of marital assets in divorce settlement.