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RENT.COM.AU LIMITED — AGM Information 2007
Mar 26, 2007
65722_rns_2007-03-26_028ac58e-9db0-43ca-be98-f3f0c84917a7.pdf
AGM Information
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Company Presentation
27 March 2007 - AGM

Developing products that target infectious diseases of global importance

Company Overview.
- Founded in 2003 (listed on ASX July 2003) $\bullet$ .
- Based in Melbourne, Australia $\bullet$ .
- · ASX Code: SLT
- Technology from the Burnet Institute $\bullet$
- $\cdot$ Board of 5
- Shares on issue: 225 million
- Number of shareholders: 1,650 approx. $\bullet$ .
- 12 staff (employees and under contract) substantial $\bullet$ research contract with the Burnet Institute

Current Position III
- $\sim$ \$7.4m market cap at a share price of 3.3c per share $\bullet$
- Twelve month share price high = 10c $\bullet$
- Twelve month share price low $=$ 2c $\bullet$
- Current cash = $$2.5m$ (31 Dec '06) $\bullet$
- Implied value of the company's technology $\sim$ \$5m $\bullet$
- Monthly cash burn currently = $$170k$ $\bullet$

ogress OvenPast 12 muis
- Virus-like particle (VLP) vaccines move further through $\bullet$ pre-clinical studies (2nd VLP patent application filed)
- Progressing with second generation HCV VLP vaccine
- Several possible manufacturers of our hepatitis C VLP $\bullet$ vaccine identified and pre-qualified
- Demonstrated that Malaria VLP vaccine produces a strong immune response in two animal species
- Completed development of two new rapid tests to proof- $\bullet$ of-concept stage (HIV and Syphilis)
- MoA and target identified in our anti-viral program (new $\bullet$ patent application filed)
- New licence signed with AVANT Immunotherapeutics, Inc. ۰ for the development of up to 3 vaccine products



- Based in Boston (MA) AVANT has extensive in-house $\bullet$ experience in vaccine development
- AVANT has a broad, well-staged pipeline, with six $\bullet$ products in clinical development
- Developed rotavirus vaccine and licensed it to GSK $\bullet$ (Rotarix®) - now earning royalties
- Has CholeraGarde® entering Phase III clinical trial and $\bullet$ Ty800 Typhoid Fever vaccine moving through Phase II trials
- Several other products under development
- Research facilities in Boston and in St Louis, MO $\bullet$
- Recently commissioned new GMP facility also in MA ۰
- They understand what it takes to develop a vaccine and they know the vaccine industry

Value Creation Opportunites
- Priority is vaccine development and exploitation of the $\bullet$ VLP platform
- Focus on collaboration and partnering to accelerate the $\bullet$ technology's development
- Third party licensees and development partners to be $\bullet$ targeted for various programs
- Specifically, vaccine companies for VLP program and drug developer for anti-viral program

Producin Developnen
- Hepatitis C vaccine E1E2-VLP vaccine $\bullet$
- Malaria vaccine MSP2 (and other vaccine candidates) $\bullet$ VLPs
- Influenza vaccine VLPs under development $\bullet$ (collaboration with AVANT Immunotherapeutics, Inc.)
- Anti-viral compounds Target ID, moving toward lead $\bullet$ selection phase
- RDTs to be placed into evaluation trials $\bullet$

WLP Vaccine Program
. . . . . . . . . . . . . . . . . . . .
| Stage of Development | Market/Revenue Potential | |||||
|---|---|---|---|---|---|---|
| Modest | Medium (\$500m+) |
High $(51b+)$ |
||||
| Marketed | ||||||
| Clinical Trials | ||||||
| Preclinical | Toxicity Test | |||||
| Process Devel. | ||||||
| In vivo (animals) | Malaria | HOV | ||||
| In vitro (cells) | HIV | HUT |
* - licensed product to AVANT Immunotherapeutics, Inc.

Kamana masa ma
Aniiviral Projectu
Our antiviral program focuses on development of drugs against picornavirus infections (estimated market >US\$400m encephalitis, meningitis, myocarditis and rhinovirus infections: $\sim$ 50% of common colds).
Anti-picornavirus Project

Diagnostics Program
| Project | R&D in Select Vaccines | Commercialisation by third party |
||||
|---|---|---|---|---|---|---|
| Proof of concept |
Performance | Technology transfer |
manufacture | Trials & regulatory approval |
Product rekaase |
|
| HEV IgM rapid test |
||||||
| HEV IgM ELISA |
||||||
| HAV IgM rapid test |
||||||
| Syphilis IgM rapid test |
||||||
| HIV rapid test | ||||||
| Avian flu rapid test |
||||||
| _# _____ |

Kabupatèn Bandaran Ing
Patent Status Marine
| Patent utile | Country | Status as at 24 March 2007 |
|---|---|---|
| Viral vector | International (PCT) | International Phase completed |
| Australia, Europe, P.R.China, United States |
$Live - pending$ Entered National Phase |
|
| Viral vector II | Australia | Filed 31 Aug 2006 Due for completion by 30 Aug 2007 |
| Binding Assay Components |
International (PCT) | Clear Written Opinion issued 25 Oct 2005 Proceed with National/Regional Phase |
| Australia, Brazil, Europe, Japan, P.R.China, United States - |
$Live - pending$ | |
| Method of diagnosis and kit therefor |
United States | $Live - pending$ |
| Peptides and Methods of Using Same |
International (PCT) | Clear Written Opinion issued 7 March 2006- Due to enter National/Regional Phase by 23 May 2007 |
| Anti-viral Compounds | International (PCT) | International phase compete |
| Australia, Canada, Europe, New Zealand, P.R.China, United States |
$Live - pending$ | |
| A method of drug design | Australia | Filed 13 Dec 2006 Due for completion by 13 Dec 2007 |

ZZZAMOWANIE W POLITYKU PRZEZ
The AVANTIDeal
- License is for 3 products the first is 'flu with total $\bullet$ milestone payments ~A\$44m (over time). Second and third products have same payment schedule
- Royalties due on sales of product(s)
- Select retains the rights to 3 VLP vaccines hepatitis C, malaria and HIV
- R&D performed in parallel by Select and AVANT with upside coming from knowledge garnered from parallel programs
- ~A\$940k invested to become 11.5% (cornerstone) shareholder (at 3.2 cents per share)
- Substantial R&D funding over 2 years (A\$650k committed by AVANT for first year)
- Funding helps strengthen the R&D program


Keykcompany Activities
In addition to our work with AVANT we are aiming to:
- Develop a stable system of expression of our VLPs (a key step in moving towards a "commercially-viable" product)
- Secure additional funding for the VLP program
- Move the anti-viral compounds to lead selection stage $\bullet$
- Complete production of sample diagnostic tests for $\bullet$ evaluation by potential third party licensees
- Put a 2nd cornerstone investor onto the register $\bullet$ .
- Launch a share purchase plan (SPP) $\bullet$
- Following the SPP, provide those shareholders still $\bullet$ holding a "small parcel" of shares with a viable opportunity to sell their shares

Future Directions
Vaccine Development
- Hepatitis C, malaria, influenza
- Vaccine development to be undertaken with partners aim is to get the vaccines into clinical trials
- If possible, "free" funding to support the vaccine program
- Development and license partners to be sought
Anti-viral Drug Development
Lead selection phase to be completed in 2007. Seeking a drug development partner for this program
Diagnostics Development
Development partners for new tests (following successful pilot study evaluation) – partner to have manufacturing and distribution capabilities

The Value Proposition
- Market valuation of the company's pipeline is currently $\bullet$ quite low
- Near term milestones will build considerable extra value $\bullet$ in the technologies under development
- Multiple product opportunities $\bullet$
- Highly respected research partners and licensees $\bullet$
- Vaccine co's and pharmaco's have these products in $\bullet$ their sights
- The company is focused on building value (not just $\bullet$ technology development)



a a sa sa sa mga mga mga mga mga mga mga mga mga mg
Enclosed (Stephender
Company Presentation
Position AfterAGM
- $\cdot$ ~255m shares on issue
- AVANT Immunotherapeutics owns $~11.5\%$ $\bullet$
- Additional \$940k cash through AVANT's equity purchase $\bullet$
