Investor Presentation • Apr 29, 2025
Investor Presentation
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April 29, 2025


Rob Koremans Chief Executive Officer
1
2
• Specialty & Primary Care
Alberto Martinez Executive VP Specialty & Primary Care
• Rare Diseases
Scott Pescatore Executive VP Rare Diseases
Luigi La Corte Chief Financial Officer
3
Rob Koremans Chief Executive Officer


3
million Euro
| REVENUE | EBITDA(1) | ADJ. NET INCOME(2) |
|---|---|---|
| 2,341.6 | 865.8 | 568.9 |
| +9.2%* vs PY | +37.0% margin | +24.3% margin |

*Pro-forma growth calculated excluding revenue of Avodart® and Combodart®/ Duodart® for both 2024 and 2023
1) Net income before income taxes, financial income and expenses, depreciation, amortization and write-downs of property, plant and equipment, intangible assets and goodwill, non-recurring items and non-cash charges arising from the allocation of the purchase price of acquisitions as foreseen by IFRS 3 to the gross margin of acquired inventory according to IFRS 3.
2) Net income excluding amortization and write-downs of intangible assets (except software) and goodwill, non-recurring items, non-cash charges arising from the allocation of the purchase price of acquisitions as foreseen by IFRS 3 to the gross margin of acquired inventory pursuant to IFRS 3, monetary net gains/losses from hyperinflation (IAS 29), net of tax effects.
Specialty & Primary Care
64% of Revenue
EBITDA margin 34.8% (in FY 2024)
Rare Diseases
36% of Revenue EBITDA margin 40.9% (in FY 2024)


Established franchises with no material loss of exclusivity and R&D investments focused on lifecycle management and geographic expansion in Rare Diseases



Strong track record in stabilizing revenue post first generic entry, with no meaningful residual LOE exposure in current SPC portfolio
Rare Diseases portfolio benefitting from long exclusivity and intrinsic protection beyond patent (formulation complexity, biologics), and lower historic generic penetration

FDA grants Isturisa®(Osilodrostat) expanded indication for the treatment of endogenous hypercortisolemia in patients with Cushing's syndrome
Signifor® LAR approved in China (following prior approvals in China for Isturisa® and Carbaglu®)
Pasireotide (Signifor®) Post-bariatric hypoglycemia (PBH)
Isturisa®/ Enjaymo® geographic expansion
Further data on mild Cushing's syndrome (already on label)
Immune thrombocytopenic purpura (ITP)

Long track record of successful execution with fast and effective integration


Group Revenue 2014-2024 & 2025 Target range

*Return on avg. invested capital 2014-2024, source Factset estimates
1) Including Chemical Division
2) 2020 figures impacted by LOE on silodosin and on pitavastatin (and COVID-19 pandemic)
3) Midpoint of targets announced at FY 2023 results in February 2024

Management team comprises highly-experienced pharmaceutical executives

Robert Koremans Chief Executive Officer

Gabriele Finzi EVP, Corporate Development

Luigi La Corte Chief Financial Officer

Alessandra Abate Group Chief People and Culture Officer

Alberto Martinez EVP, SPC Business Unit

Bibianne Bon Group Chief Legal Officer

Scott Pescatore EVP, RRD Business Unit


Milan Zdravkovic EVP, Head of R&D

Alessandro Gilio Executive VP Group Industrial Operations




Rob Koremans Chief Executive Officer
1
2
• Specialty & Primary Care
Alberto Martinez Executive VP Specialty & Primary Care
• Rare Diseases
Scott Pescatore Executive VP Rare Diseases 2025-2027 Financial projections
Luigi La Corte Chief Financial Officer
3
Rob Koremans Chief Executive Officer


*Including Chemical Division
13



~ 60% of volumes manufactured by Recordati plants
Majority of CMOs based in Europe and in US
Producing API for several key products for both SPC and RRD
Stable 3rd party API revenue of ~€ 50 million


Strong brand loyalty across S. Europe, CEE and Türkiye offsetting minimal price erosion in N. Europe, with net positive average pricing on total business of ~1%/ year (excl. Türkiye)

European Market Outlook* 2024-2027 Billion Euro

*All Europe - Source IQVIA
1) ATC G4 Urologicals; (2) ATC C Cardiovascular; (3) ATC A Alimentary tract (excludes A8, Obesity and A10, Diabetes)


Uniquely diversified business of brand originator products with direct presence in 30 markets leveraging

Improving competitiveness and optimizing portfolio through clear focus and enhanced capabilities
Timely transformation since 2021 built on 4 key pillars:


EBITDA ratio steady increase from 33% to 35% since 2022

~€200m growth at 7.3% CAGR since 2022

million Euro

Main products represent ~77% of Urology revenue with growth driven by:
Growth in Prostate cancer (Eligard®) and Benign Prostatic Hyperplasia (Urorec®, Avodart®/ Combodart®) markets driven by:

Eligard Evolution Index(1) Sep 2020 - Jan 2025

Highlights
Revenue declining before product was in-licensed in March 2021
Eligard® identified as a priority growth brand
New device successfully launched through 2024, driving double-digit growth and market share gains
Expectations of mid single-digit CAGR 2024-2027, taking into account new competitive entries
1) Evolution index calculated based on LEU (Local Currency Euro) on market where IQVIA data is available 2) 2021 Eligard: Recordati booked net margin as Revenue until distribution transfer from Astellas in 2021

Cardiovascular Revenue

Growth in Hypertension (Zanidip®/ Zanipress®, Seloken®/Betaloc®) and Hypercholesterolemia (Livazo®) markets expected to be driven by:
1) Includes all brands with same active ingredients

Gastrointestinal, Cough & Cold, Other Pharma revenue million Euro

Revenue 50% OTC and 50% RX with majority of growth driven by OTC brands in Italy, Spain & CEE
Most of revenue generated in RX (~ 75%) but with majority of growth coming from OTC brands in Russia, France and Italy
Revenue 50% OTC and 50% RX with majority of growth driven by OTC brands in Southern Europe

Revenue actual and 2025-2027 plan million Euro

Sales growing ~3.5-4.5% CAGR at CER, with adverse FX approx. -1.5%
Resilient margins thanks to focused strategy leveraging competitive and cost-effective commercial capabilities
Rx-Prescription segment with negligible LoE sustaining low single-digit growth
segment boosting overall SPC growth to mid-single digits thanks to positive contribution of volume and price


Rob Koremans Chief Executive Officer
1
2
• Specialty & Primary Care
Alberto Martinez Executive VP Specialty & Primary Care
• Rare Diseases
Scott Pescatore Executive VP Rare Diseases
Luigi La Corte Chief Financial Officer
3
Rob Koremans Chief Executive Officer


Most rare diseases do not have an approved pharmaceutical treatment and even if available, low diagnosis rates remain

Protection beyond IP expiration, often more expensive and complicated to manufacture (especially biologics); slower erosion post-Gx due to strong product loyalty

Total worldwide rare diseases revenue expected to almost double in the next years, outpacing revenue growth of other prescription & generics counterparts(1)

Shorter duration of clinical development with smaller patient populations and faster regulatory review processes
(1) Reference:https://www.evaluate.com/thought-leadership/orphan-drugs-2025-report/
(2) Reference: Frontiers | Clinical development and marketing application review times for novel orphan-designated drugs https://ojrd.biomedcentral.com/articles/10.1186/s13023-018-0990- 4?utm\_source=chatgpt.com https://www.tandfonline.com/doi/full/10.4155/fmc-2019-0307
Out of >7,000 known rare diseases, only ~5% have approved product available
Global Rare Diseases market(1) 2024: \$ 187 billion 2030* : \$ 333 billion
7 years orphan drugs 10-15 years other pharmaceuticals

Revenue 2008 - 2024





Endocrinology Revenue million Euro

1) Pivonello R et al. Lancet Diabetes Endocrinol 2020;8:748–61;Gadelha M et al. J Clin Endocrinol Metab 2022;107:e2882–95; 4;Fleseriu M, et al. Pituitary. 2025 Jan 25;28(1):22;https://www.ema.europa.eu/en/documents/product-information/isturisa-epar-product-information_en.pdf; 2) Gadelha MR et al. Lancet Diabetes Endocrinol. 2014 Nov;2(11):875-84; Stelmachowska-Banaś et al. Pituitary 2022;25(1):180–190


Isturisa U.S. Patients

Broader label unlocks significantly larger opportunity with further additional growth from Cushing's disease
Provides full access to Cushing's syndrome patients suffering from hypercortisolemia, independent of etiology
Differentiated clinical profile with favorable impact on secondary implications of hypercortisolemia (blood pressure, diabetes and body-weight(1))
1) Pivonello R et al. Lancet Diabetes Endocrinol 2020;8:748–61;Gadelha M et al. J Clin Endocrinol Metab 2022;107:e2882–95; 4; Fleseriu M, et al. Pituitary. 2025 Jan 25;28(1):22; https://www.ema.europa.eu/en/documents/product-information/isturisa-epar-productinformation_en.pdf;

Hema-Oncology Revenue million Euro

1) SIOPEN Research Network
2) QARZIBA® (dinutuximab beta). Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/9441. Accessed: February 2024.
3) Ladenstein R, et al. Cancers. 2020;12:309.
iMCD: Idiopathic Multicentric Castleman Disease


POTENTIAL FUTURE TREATMENT CURRENT TREATMENT 1L MAINTAINANCE MAINTENANCE R/R INDUCTION RELAPSED REFRACTORY CHEMO maintenance setting.1,2,3 therapy) 5 INDUCTION THERAPY CHEMO 1L MAINTAINANCE MAINTENANCE R/R
Data above is based on: a. https://www.ncbi.nlm.nih.gov/pmc/articles b. Data for CR+VGPR+PR similar in Berhold 2020 (89%) vs 87.6% in Moreno 2018
Highlights
Qarziba® is an anti-GD-2 monoclonal antibody which is the recommended standard of care for children with high-risk neuroblastoma in the
Currently indicated in EU for 1L maintenance and 2L relapsed/ refractory high-risk neuroblastoma
Opportunity to move into the US in relapsed/refractory4 and exploring 1L (induction
1) SIOPEN Research Network
2) QARZIBA® (dinutuximab beta). Summary of Product Characteristics. Available at:
https://www.medicines.org.uk/emc/product/9441. Accessed: February 2024.
24); HRNBL2 (NCT04221035) 5) SIOPEN Pilot (NCT06485947)

33



Revenue expected be broadly stable
Solid and differentiated portfolio of 15 products serving patients with rare metabolic conditions
Medication to treat hyperammonemia, a genetic condition characterized by elevated levels of ammonia in the blood, associated with severe neurotoxicity
Only medication for amelioration of recurrent attacks of acute intermittent porphyria (AIP), a rare genetic disorder that affects the production of heme

Global market-leading eye treatment for patients with cystinosis, a rare genetic condition that leads to the accumulation of cystine in various organs, including the eye

Focus on brands with exclusivity in relevant geographies and countries with unmet medical needs

Geographic expansion (Carbaglu in China, Cystadrops in Japan)

Targeted investments and leverageable commercial infrastructure sustain strong profitability



sales of five key products
| PRODUCT | 2024 REVENUE (€ M) | Peak Year Sales (PYS) targets (€ M) |
Future growth drivers | |
|---|---|---|---|---|
| O D N E |
204 | (1) 550 – 650 |
Favorable market dynamics (increasing treatment rates) • Cushing syndrome label in US • Potential extension of US exclusivity to 2033 (from 2031)(2) • • Successful national reimbursement in China |
|
| 118 | 150 – 200 |
Opportunity to move up treatment paradigm in Acromegaly • • Potential new indication: Post-Bariatric Hypoglycemia (PBH); additional € 150M opportunity (not included in PYS, enrollment completion by mid-2025) |
||
| 322 | ~700 – 850 |
Broader penetration in EU • |
||
| O C N O - A M E H |
227 | 300 – 350 |
• US approval for relapsed/refractory patients (included in PYS, FDA meeting to discuss further clinical data analysis mid-2025) Potential new indication: Ewing sarcoma (not included in PYS, • clinical study expected to initiate in H1 2025) |
|
| Significant scope for improved awareness and diagnosis • |
||||
| 116 | 250 – 300 |
Evaluate potential new indications (not included in PYS) such as • immune thrombocytopenic purpura (ITP) and geographic expansion |
||
| 343 | ~550 – 650 |
1) Previous PYS target: €500-600 M 37 2) LOE U.S.: 2031 (2033 pending patent term extensions), last Orange Book patents expire 2035 |

Rob Koremans Chief Executive Officer
1
2
• Specialty & Primary Care
Alberto Martinez Executive VP Specialty & Primary Care
• Rare Diseases
Scott Pescatore Executive VP Rare Diseases
Luigi La Corte Chief Financial Officer
3
Rob Koremans Chief Executive Officer


BD and M&A remain a key and integral part of Group strategy; growth over last decade broadly 50-50 organic/ BD, with organic momentum accelerating in more recent years
FY 2027 Targets assume range of realistic scenarios for development of current portfolio (SPC organic CAGR, RRD speed of ramp up on key assets) and of FX headwinds (-1%/-2%)
FY 2027 Targets also build in expected contribution from potential new deals, assuming a mix of deal types:
Ongoing lifecycle management projects expected to contribute to growth post 2027 (accelerating 2030 onwards)

| Macro | Pricing and reimbursement broadly in-line with current environment • Potential impact of US tariffs not included • FX headwinds of just approx. -1% to –2% per annum, impacting both SPC (TRY) and RRD (USD) • Inflation in low to mid-single digit across key geographies and slightly reducing interest rates • |
|---|---|
| Revenue | Robust organic growth of both businesses, driven by volume • YoY pricing expected to be net positive (approx. +1%/ year, excl Türkiye) • No material impact from new LOEs • • Bolt-on acquisitions and new licenses included in 2027 targets (mix of deal types) |
| Margin and Profitability |
Operating leverage and shifting mix to rare disease support underlying margin improvement • Plan to continue targeted investments to support key growth areas (incl RRD geographic expansion) • • Maintain R&D investments around 7% of revenue (excl. amortization) to support lifecycle management • Tax rate broadly in line with current levels ~24% |


| million Euro | FY 2024 Actual |
FY 2025 Target |
FY 2027 Target (incl. BD & M&A) |
CAGR* 2024-2027 (mid-point) |
|---|---|---|---|---|
| Revenue yoy growth |
2,341.6 | 2,600 – 2,670 |
3,000 – 3,200 |
+9.8% |
| EBITDA (1) margin on sales |
865.8 37.0% |
970 – 1,000 +/- 37.5% |
1,140 – 1,225 ≥38% |
+11.0% |
| Adjusted Net Income (2) margin on sales |
568.9 24.3% |
640 – 670 +/- 25% |
770 – 820 +/- 25.5% |
+11.8% |
*CAGR at mid-point of guidance range
1) Net income before income taxes, financial income and expenses, depreciation, amortization and write-downs of property, plant and equipment, intangible assets and goodwill, non-recurring items and non-cash charges arising from the allocation of the purchase price of acquisitions as foreseen by IFRS 3 to the gross margin of acquired inventory according to IFRS 3.
2) Net income excluding amortization and write-downs of intangible assets (except software) and goodwill, non-recurring items, non-cash charges arising from the allocation of the purchase price of acquisitions as foreseen by IFRS 3 to the gross margin of acquired inventory pursuant to IFRS 3, monetary net gains/losses from hyperinflation (IAS 29), net of tax effects.

| Drive organic growth of diversified business |
Sustain high level of profitability |
Pursue targeted pipeline opportunities |
Maintain clear capital allocation policy |
||
|---|---|---|---|---|---|
| Strong underling volume growth over the period of current portfolio across both business segments |
Maintain sector leading operating and bottom-line margin as % of revenue |
Targeted clinical opportunities with the potential to turn into commercial success |
~50% | Progressive dividend pay-out |
|
| SPC Mid-single digit growth at CER |
RRD Double-digit growth at CER |
EBITDA Margin ≥38% by 2027 |
Cash R&D at ~7% of revenue | ~50% | Accretive & growth bolt-on M&A and BD |
| Strong cash flow generation & robust balance sheet | ||||
|---|---|---|---|---|
| Free cash flow conversion ~90% of Adjusted Net Income |
Net Debt / EBITDA target to stay at 1.7-2x |
Flexibility to go up to max of close to 3x for larger scale, high quality opportunities |
Note: financial planning assumptions provided up to 2025 1) With current portfolio alone 2) Excluding amortization




Statements contained in this presentation, other than historical facts, are "forward-looking statements" (as such term is defined in the Private Securities Litigation Reform Act of 1995). These statements are based on currently available information, on current best estimates, and on assumptions believed to be reasonable by Management. This information, these estimates and assumptions may prove to be incomplete or erroneous, and involve numerous risks and uncertainties, beyond the Company's control.
These risks and uncertainties include among other things, the uncertainties inherent in pharmaceutical marketing and development, impact of decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug or biological application that may be filed as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of our products, the future approval and commercial success of therapeutic alternatives, Recordati's ability to benefit from external growth opportunities, to complete capital markets or other transactions and/or obtain regulatory clearances, risks associated with intellectual property and any related pending or future litigation and the ultimate outcome of such litigation, trends in exchange rates and prevailing interest rates, volatile economic and capital market conditions, cost containment initiatives by payors of medicines and subsequent changes thereto, and the impact that pandemics, political disruption or armed conflicts or other global crises may have on our business.
Hence, actual results may differ materially from those expressed or implied by such forward-looking statements. All mentions and descriptions of Recordati products are intended solely as information on the general nature of the company's activities and are not intended to indicate the advisability of administering any product in any particular instance.
Recordati (Reuters RECI.MI, Bloomberg REC IM) is an international pharmaceutical group listed on the Italian Stock Exchange (ISIN IT 0003828271) uniquely structured to bring treatment across specialty and primary care and rare diseases. We believe that health, and the opportunity to live life to the fullest, is a right, not a privilege. We want to support people in unlocking the full potential of their lives. We have fully integrated operations across research & development, chemical and finished product manufacturing through to commercialization and licensing. Established in 1926, Recordati operates in approximately 150 countries across EMEA, Americas and APAC regions. At the end of 2023, Recordati employed over 4,450 people and consolidated revenue of € 2,082.3 million. For more information, please visit www.recordati.com
The manager responsible for preparing the company's financial reports Luigi La Corte declares, pursuant to paragraph 2 of Article 154-bis of the Consolidated Law on Finance, that the accounting information contained in this presentation corresponds to the document results, books and accounting records.
Recordati S.p.A. Via M. Civitali 1 20148 Milano, Italy

Investor Relations: Eugenia Litz +44 7824 394 750 [email protected]

Investor Relations: Gianluca Saletta +39 348 9794876 [email protected]
Website: www.recordati.com


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