Q32 Bio Inc. — Director's Dealing 2025

Oct 28, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Q32 Bio Inc. (QTTB)
CIK: 0001661998
Period of Report: 2025-10-23

Reporting Person: GRAYZEL DAVID S. (N/A)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-23	Stock Option (Right to Buy)	$2.80	A	53521	Acquired	2035-10-22	Common Stock (53521)	Direct

Footnotes

F1: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F2: This option was granted to the Reporting Person, a director of the Issuer. The proceeds of any sale of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Life Science Advisors, LLC and as such, the Reporting Person disclaims ownership of such securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.