Q32 Bio Inc. — Director's Dealing 2025

Oct 28, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Q32 Bio Inc. (QTTB)
CIK: 0001661998
Period of Report: 2025-10-23

Reporting Person: Xu Diyong (N/A)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-23	Stock Option (Right to Buy)	$2.80	A	53521	Acquired	2035-10-22	Common Stock (53521)	Direct

Footnotes

F1: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F2: Pursuant to an agreement with OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, the Reporting Person is obligated to transfer any securities issued under any such stock options or other awards, or the economic benefit thereof, to OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, which will in turn ensure that such securities or economic benefits are provided to OrbiMed Private Investments VII, LP.