PYC THERAPEUTICS LIMITED — Share Issue/Capital Change 2011

Jul 26, 2011

PHYLOGICA LIMITED ABN 48 098 391 961

REGISTERED OFFICE PHYLOGICA LIMITED SUITE 3 257 YORK STREET SUBIACO WA 6008

SHARE REGISTRY Security Transfer Registrars Pty Ltd All Correspondence to: PO BOX 535, APPLECROSS WA 6953

Tel (08) 9315 2333 Fax (08) 9315 2233 EMAIL: registrar@securitytransfer.com.au

27[th] July 2011

Dear Option Holder

YOUR OPTIONS TO ACQUIRE PHYLOGICA LIMITED SHARES AT $0.15 PER SHARE EXPIRE ON 31[ST] August 2011

We are writing to you as a registered holder of listed options in PHYLOGICA LIMITED to remind you that the options will expire at 5:00pm (WST) on 31[st] August 2011.

Your option holding may be exercised in whole or in part by payment of $0.15 for each option by no later than 31[st] August 2011. If payment is not received by 5:00pm (WST) on 31[st] August 2011 the options will lapse and all rights under the options will cease at that time.

Some of the courses of action available to you as a holder of these soon to expire options are:

• a) Exercise the options on or before 31[st] August 2011.

• b) Sell your options. Quotation of the options will cease at the close of trading on 24[th] August 2011.

• c) Do nothing (ie, allow your options to expire). If you do not exercise or sell your options they will expire on 31[st] August 2011 and your right to subscribe for ordinary shares in PHYLOGICA LIMITED at $0.15 per share will lapse.

There is no obligation on option holders to exercise their options. However, under paragraph 6.1 of Appendix 6A of the Australian Securities Exchange ( ASX ) Listing Rules, the Company is required to advise option holders of the information contained in this notice.

The market sale price of ordinary shares in PHYLOGICA LIMITED on ASX was 7.3 cents on 26[th] July 2011, being the last trading day in Perth prior to the date of this notice.

During the three (3) months preceding the date of this notice:

• the highest market sale price of ordinary shares on ASX was 8.6 cents on 13[th] July 2011; and

• the lowest market sale price of ordinary shares on ASX was 6.0 cents on 18[th] May 2011.

If you wish to exercise your options then you must complete your “Notice of Exercise of Options” form on the reverse of this notice and forward it together with payment of $0.15 per option exercised to be received no later than 5:00pm (WST) on 31[st] August 2011 to the Company’s share registry, being:

Security Transfer Registrars Pty Ltd PO Box 535 OR 770 Canning Highway APPLECROSS WA 6953 APPLECROSS WA 6153

Cheques should be made payable to “ PHYLOGICA LIMITED ” in Australian dollars only and should be crossed “Not negotiable”. If you have any further questions please do not hesitate to contact our Registry on telephone (08) 9315 2333, facsimile (08) 9315 2233, or e-mail registrar@securitytransfer.com.au.

Yours faithfully PHYLOGICA LIMITED

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Graeme Boden

COMPANY SECRETARY