PYC THERAPEUTICS LIMITED — Director's Dealing 2024

Mar 27, 2024

Rule 3.19A.2

Appendix 3Y

Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity	PYC THERAPEUTICS LIMITED
ABN	48 098 391 961

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Alan William Tribe
Date of last notice	14 July 2023

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Direct or indirect interest	INDIRECT
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to the relevantinterest.	Mr Tribe is a Director of Australian Land PtyLtd, Delarge Investments Pty Ltd, RunctonPty Ltd, Pagham Pty Ltd, StockbridgeCorporation Pty Ltd, Trexon Pty Ltd andLocca Pty Ltd
Date of change	26 March 2024
No. of securities held prior to change	1,229,813,974ordinary shares
Class	Ordinary shares
Number acquired	307,453,493
Number disposed	-
Value/ConsiderationNote: If consideration is non-cash, provide details and estimatedvaluation	$24,596,279
No. of securities held after change	1,537,267,467

+ See chapter 19 for defined terms.

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Part 2 – Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should be disclosed in this part.

Detail of contract
Nature of interest
Name of registered holder
(if issued securities)
Date of change
No. and class of securities to which interest
related prior to changeNote: Details are only required for a contract in relation to which theinterest has changed
Interest acquired
Interest disposed
Value/ConsiderationNote: If consideration is non-cash, provide details and an estimatedvaluation
Interest after change

Part 3 – +Closed period

Weretheinterestsinthesecuritiesorcontractsdetailedabovetradedduringa+closed periodwhere prior written clearancewas required?	No
If so, was prior written clearance provided toallow the trade to proceed during this period?
If prior written clearance was provided, onwhat date was this provided?

+ See chapter 19 for defined terms.