PROTHENA CORP PUBLIC LTD CO — Director's Dealing 2021

Feb 17, 2021

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PROTHENA CORP PUBLIC LTD CO (PRTA)
CIK: 0001559053
Period of Report: 2021-02-12

Reporting Person: Tripuraneni Radhika (Chief Development Officer)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2021-02-12	Employee Stock Option (Right to Buy)	$35.24	D	50000	Disposed	2028-04-02	Ordinary Shares (50000)	Direct
2021-02-12	Employee Stock Option (Right to Buy)	$22.85	A	37037	Acquired	2028-04-02	Ordinary Shares (37037)	Direct

Footnotes

F1: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on April 2, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

F2: On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 50,000 of the issuer's ordinary shares granted to the reporting person on April 2, 2018. In exchange, the reporting person received a replacement option, for 37,037 ordinary shares, having an exercise price of $22.85 per ordinary share.

F3: The shares subject to the option will vest and become exercisable as to 46/48 of the total number of shares subject to the option on the one year anniversary of the date of grant, with respect to 1/48 of the total number of shares subject to the option on March 2, 2022 and with respect to 1/48 of the total number of shares subject to the option on April 2, 2022, subject to the reporting person's continued service with the issuer on each such vesting date.