PROTHENA CORP PUBLIC LTD CO — Director's Dealing 2016

Nov 30, 2016

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Prothena Corp plc (PRTA)
CIK: 0001559053
Period of Report: 2016-11-28

Reporting Person: Selkoe Dennis J. (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2016-11-28	Ordinary Shares, par value $0.01 per share	M	5000	$16.42	Acquired	7845	Direct
2016-11-28	Ordinary Shares, par value $0.01 per share	S	4100	$62.1674	Disposed	3745	Direct
2016-11-28	Ordinary Shares, par value $0.01 per share	S	900	$63.5911	Disposed	2845	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2016-11-28	Stock Option (right to buy)	$16.42	M	5000	Disposed	2023-07-21	Ordinary Shares (5000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares, par value $0.01 per share	1363	Indirect

Footnotes

F1: The sale reported on this Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person.

F2: The transaction was executed in multiple trades in prices ranging from $61.76 to $62.64, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected.

F3: The transaction was executed in multiple trades in prices ranging from $62.88 to $63.68, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected.