PRECIGEN, INC. — Director's Dealing 2025

Dec 23, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PRECIGEN, INC. (PGEN)
CIK: 0001356090
Period of Report: 2025-12-22

Reporting Person: KIRK RANDAL J (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-22	Common Stock	S	555119	$4.18	Disposed	81609648	Indirect
2025-12-22	Common Stock	S	12909	$4.18	Disposed	477492	Indirect
2025-12-22	Common Stock	S	94341	$4.18	Disposed	3609057	Indirect
2025-12-22	Common Stock	S	38729	$4.18	Disposed	1615634	Indirect
2025-12-22	Common Stock	S	12909	$4.18	Disposed	476529	Indirect
2025-12-22	Common Stock	S	159321	$4.18	Disposed	3785116	Indirect
2025-12-22	Common Stock	S	42702	$4.18	Disposed	1594338	Indirect
2025-12-22	Common Stock	S	11917	$4.18	Disposed	566162	Indirect
2025-12-22	Common Stock	S	9931	$4.18	Disposed	341189	Indirect
2025-12-22	Common Stock	S	5958	$4.18	Disposed	447773	Indirect
2025-12-22	Common Stock	S	956200	$4.18	Disposed	4598044	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	1403	Indirect
Common Stock	6085471	Indirect
Common Stock	1096686	Indirect
Common Stock	14597161	Indirect
Common Stock	1144481	Indirect

Footnotes

F1: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.1800 to $4.1900, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4.

F2: Randal J. Kirk controls each of R.J. Kirk Declaration of Trust ("R.J. Kirk DOT"), JPK 2008 LLC ("JPK 2008"), JPK 2009 LLC ("JPK 2009"), JPK 2012 LLC ("JPK 2012"), MGK 2008 LLC ("MGK 2008"), MGK 2009 LLC ("MGK 2009"), MGK 2011 LLC ("MGK 2011"), ZSK 2008 LLC ("ZSK 2008"), ZSK 2009 LLC ("ZSK 2009"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Kapital Joe, LLC ("Kapital Joe"), Lotus Capital (2000) Company, Inc. ("Lotus"), Third Security, LLC ("Third Security"), Parkview 2020 Limited Partnership ("Parkview 2020") and Sunset 2020 LLC ("Sunset 2020"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.