PLUS THERAPEUTICS, INC. — Director's Dealing 2025

Oct 3, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PLUS THERAPEUTICS, INC. (PSTV)
CIK: 0001095981
Period of Report: 2025-10-01

Reporting Person: Sims Andrew John Hugh MacIntyre (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-10-01	Common Stock	M	38323	—	Acquired	48138	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-01	Restricted Stock Units	$0	M	38323	Disposed		Common Stock (38323)	Direct

Footnotes

F1: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the issuer's Common Stock.

F2: Represents the vesting of an RSU grant which occurs in twelve substantially equal quarterly installments beginning on October 1, 2025.