Regulatory Filings • Oct 30, 2017
Regulatory Filings
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30 באוקטובר 2017
על פי תשקיף מדף של החברה מיום 14 בספטמבר 2017 כפי שפורסם ביום 13 בספטמבר 2017 )מספר אסמכתא: 2017-02-081472( )להלן: "תשקיף המדף"(, ובהתאם להוראות תקנות ניירות ערך )הצעת מדף של ניירות ערך(, התשס״ו,2005- מתכבדת החברה לפרסם בזאת דוח הצעת מדף להנפקה ולרישום למסחר של ניירות ערך של החברה כמפורט להלן )להלן: ״דוח הצעת המדף״(.
בדוח הצעת מדף זה תיוחס למונחים המובאים בו המשמעות שיוחסה להם בתשקיף המדף, אלא אם כן צוין אחרת בדוח הצעת המדף.
דוח הצעת מדף זה הינו הצעה ראשונה לציבור על בסיס תשקיף המדף.
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בד ובד עם הצעת ניירות הערך בישראל על פי דוח הצעת מדף זה, תרשום החברה בארה"ב, באמצעות תשקיף המדף האמריקאי, כפי שפורסם ביום 23 ביוני 2017 )מס' אסמכתא: 2017-02-064398( והמצ"ב כנספח ב' לדוח זה ומסמך רישום, בהתאם לדיני ניירות ערך של ארה"ב )להלן: "תשקיף המדף האמריקאי" ו- "דו"ח הצעת המדף האמריקאי" בהתאמה( )להלן ביחד: "התשקיף האמריקאי"(, את ניירות הערך המפורטים בסעיף 1 להלן, כאשר ההצעה על פי דו"ח הצעת מדף זה ועל פי התשקיף האמריקאי הינה הצעה אחת של ניירות הערך 1 המוצעים .
מובהר כי האמור לעיל הינו בהתאם לדיני ניירות הערך של ארה"ב ומחליף את האמור בעמודים ,2 4 ו- 6 בתשקיף המדף הישראלי לעניין ההצעה בארה"ב.
עד 9,000,000 מניות רגילות, של החברה בנות 0.00001 דולר ארה"ב ערך נקוב כ"א )להלן: "המניות המוצעות" או "ניירות הערך המוצעים"(.
לפירוט ההון המונפק והנפרע של החברה, לאחר השלמת ההנפקה על פי דוח הצעת המדף ובהנחה של הנפקת כל ניירות הערך המוצעים, ראה סעיף 2 לדוח הצעת המדף.
למועד דוח הצעת מדף זה הונה הרשום של החברה הינו 200,000,000 מניות רגילות, בנות 0.00001 דולר ארה"ב ערך נקוב כ"א.
| המדף דוח הצעת קה על פי למת ההנפ לאחר הש |
ף צעת המד ערב דוח ה |
||
|---|---|---|---|
| ניות ונפרע במ הון מונפק הערך קת ניירות לאחר הנפ בדילול ההצעה, על-פי דוח מלא |
ניות ונפרע במ הון מונפק הערך קת ניירות לאחר הנפ ההצעה על-פי דוח |
ונפרע הון מונפק 2 דילול מלא במניות, ב |
ונפרע הון מונפק במניות |
| 126,337,762 | 107,947,746 | 117,337,762 | 98,947,746 |
.2.1 המניות המוצעות על פי דוח הצעת המדף, תהוונה לאחר השלמת ההנפקה על פי דוח הצעת המדף, בהנחה של הנפקת כל המניות המוצעות על פי דוח הצעת המדף, כ- 8.33% מהון המניות המונפק והנפרע של החברה וכ- 7.12% בדילול מלא.
.3.1 ניירות הערך מוצעים לציבור ב- 90,000 יחידות בדרך של מכרז על מחיר יחידה שהרכב כל יחידה ומחירה המינימאלי הינם כדלקמן:
| ביחידה הערך ניירות כמות |
ערך לנייר מינימאלי מחיר |
סה"כ |
|---|---|---|
| רגילות מניות 100 |
ה ש"ח למני 5.7 |
ש"ח 570 |
| ליחידה לי המינימא המחיר |
ש"ח 570 |
התקופה להגשת הזמנות לרכישת היחידות המוצעות לציבור במסגרת המכרז כאמור בסעיף 3.3 שלהלן, תחל ביום ב', 30 באוקטובר ,2017 בשעה 9:00 )להלן: "מועד פתיחת רשימת החתימות"( ותסתיים בשעה 17:30 באותו היום )להלן: ״מועד סגירת רשימת החתימות״ ו- "יום המכרז"( )ובלבד שהתקופה להגשת הזמנות תסתיים לא לפני שחלפו לפחות שבע שעות ומתוכן חמש שעות מסחר ממועד פרסום דוח הצעת המדף(.
החברה רשאית לבטל את ההצעה בכל עת עד למועד סגירת רשימת החתימות מבלי שתהיה למשקיעים כל טענה בקשר לכך. במקרה כאמור, יראו את ההזמנות שניתנו לחברה בקשר עם
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בהנחה שכל ניירות הערך ההמירים המונפקים במועד הרלוונטי ימומשו למניות רגילות )להלן: "דילול מלא"(.
של המשקיעים מסווגים שהתקשרו בהתקשרות מוקדמת עם החברה, כאמור בסעיף 4.2 לדו"ח(.
.3.5.4 אם בהקצאת ניירות הערך המוצעים על פי ההיענות במכרז כאמור לעיל ייווצרו שברי יחידות הם יעוגלו, ככל הניתן, ליחידה השלמה הקרובה ביותר. עודפים של יחידות שינבעו כתוצאה מהעיגול כאמור יירכשו על ידי רכז ההנפקה, במחיר המינימאלי ליחידה.
.4.1 מתוך היחידות המוצעות לציבור, לגבי 71,237 יחידות, המהוות כ- 79.15% מסך היחידות המוצעות בדוח הצעה זה, ניתנו התחייבויות מוקדמות לרכישתן על ידי משקיעים מסווגים, כהגדרתם בסעיף 1 לתקנות אופן הצעה לציבור 3 , לפיהן יגישו המשקיעים המסווגים בקשות לרכישת יחידות במחיר ליחידה, ובכמויות המפורטות להלן בסעיף .4.2
"חתימת יתר"- היחס שבין כמות ניירות הערך שהוגשו לגביהם הזמנות במחיר האחיד ליחידה שיקבע במכרז, לבין הכמות שנותרה לחלוקה כהגדרתה להלן, ובלבד שהוא עולה על אחד.
"הכמות שנותרה לחלוקה"- כמות ניירות הערך שהוצעה במכרז על מחיר היחידה על פי דוח הצעת המדף, לאחר שנוכתה כמות ניירות הערך שהוגשו לגביהם הזמנות במחיר ליחידה הגבוה מהמחיר ליחידה האחיד שנקבע במכרז.
במקרה של חתימת יתר, הקצאה למשקיע מסווג לפי התחייבות מוקדמת שנתן תיעשה באופן הבא:
הזמנות המשקיעים המסווגים תיחשבנה הזמנות שהוגשו על ידי הציבור לצורך קביעת המחיר האחיד ליחידה. ההקצאה למשקיעים המסווגים תהיה במחיר היחידה כפי שנקבע במכרז.
במקרה שלא תתקיים חתימת יתר, תיחשבנה הזמנות המשקיעים המסווגים במסגרת המכרז כהזמנות שהוגשו על ידי הציבור לצורך חלוקת היחידות למזמינים.
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כל אחד מהמשקיעים המסווגים, המפורטים להלן, התחייב במסגרת התחייבות מוקדמת לרכישת המניות המועצות על פי דוח הצעת מדף זה, להגיש בקשות לרכישת יחידות המניות המוצעות, ביחד ליחידה, כמפורט להלן:
"משקיע מסווג"- אחד מאלה: )1( מנהל תיקים כמשמעותו בסעיף 8)ב( לחוק הייעוץ חוק הסדרת העיסוק בייעוץ השקעות ובניהול תיקי השקעות, התשנ"ה,1995- הרוכש לפי שיקול דעתו לחשבונו של לקוח; )2( תאגיד הנמצא בבעלות מלאה של משקיע מסווג, אחד או יותר, הרוכש לעצמו או למשקיע מסווג אחר; )3( משקיע המנוע בסעיף 15א)ב()2( לחוק ניירות ערך; או )4( משקיע המנוי בפרטים )1( עד )9( או )11( בתוספת הראשונה לחוק ניירות ערך, הרוכש עבור עצמו. כמו כן, על משקיע מסווג להתחייב לרכוש ניירות ערך בהנפקה בהיקף כספי של 800 אלפי ש"ח לפחות.
| יחידות | )בש"ח( מחיר |
שם |
|---|---|---|
| 3,500 | 570 | מ הון בע" חים שוקי א.ב. מרוו |
| 8,350 | 590 | ות בע"מ* אסטרטגי אורקום |
| 5,000 | 570 | ות בע"מ* אסטרטגי אורקום |
| 2,000 | 690 | מוגבלת שותפות שחם נץ אלטשולר |
| 2,000 | 580 | מוגבלת שותפות שחם נץ אלטשולר |
| 1,560 | 680 | בע"מ ופ חיתום אם.די. גר |
| 1,500 | 650 | בע"מ ופ חיתום אם.די. גר |
| 5,200 | 700 | בע"מ* ות 2006 טל השקע ברק קפי |
| 3,360 | 580 | בע"מ* ות 2006 טל השקע ברק קפי |
| 1,800 | 600 | מ גנוס בע" |
| 2,700 | 580 | ץ בע"מ* ה.ע.ק יעו |
| 2,000 | 570 | ץ בע"מ* ה.ע.ק יעו |
| 1,700 | 570 | גבלת ותפות מו חצבים ש |
| 1,900 | 570 | ים בע"מ* ענבר נגזר |
| 1,455 | 700 | מ פיטל בע״ פיינאל ק |
| 2,500 | 570 | מ דים בע" מוצרי מד דות סל ו קסם תעו |
| 6,000 | 600 | בלת* תפות מוג ת ערך שו ת בניירו להשקעו קרן בזלת |
| 3,700 | 640 | ת בע"מ* והשקעו ריט ניהול ר.י.ל ספי |
| 4,500 | 610 | ת בע"מ* והשקעו ריט ניהול ר.י.ל ספי |
| 4,265 | 710 | עוף בע"מ קעות במ שקף הש |
| 1,747 | 650 | בע"מ עוף קעות במ שקף הש |
| 1,500 | 600 | מ דדים בע" תכלית מ |
| 3,000 | 580 | מ דדים בע" תכלית מ |
| 71,237 | סה"כ |
)*( משקיע מסווג שהוא קשור למפיץ בהנפקה.
לאור האמור לעיל, ניתנה התחייבות מוקדמת על ידי משקיעים מסווגים לרכישת 42,710 יחידות המהוות כ- 60% מסך ההתחייבויות המוקדמות שניתנו על ידי משקיעים מסווגים.
התחייבויות המשקיעים המסווגים האמורים בס"ק 4.2 תקראנה בסעיף זה – "התחייבות מוקדמת".
.4.3 קבלת התחייבויות מוקדמות מהמשקיעים המסווגים ערב פרסום דוח הצעת מדף זה נעשתה על פי
העקרונות הקבועים בתקנות הצעה לציבור וכן כמפורט בסעיף 4.1 לדוח זה.
.5.1 המניות המוצעות הינן שוות זכויות לכל דבר ועניין, למניות הרגילות בנות 0.00001 דולר ארה"ב ערך נקוב כ"א של החברה הקיימות בהונה המונפק של החברה במועד דוח הצעת המדף, ובכלל זה יזכו את בעליהן בכל דיבידנד ובכל חלוקה אחרת שהמועד הקובע את הזכות לקבלה הינה במועד הקצאתן או מאוחר יותר.
לפרטים אודות הזכויות הנלוות למניות הרגילות של החברה ראה V ARTICLE בתקנון החברה (AMENDED AND החברה של ההתאגדות ומסמכי( AMENDED AND RESTATED BYLAWS( (INCORPORATION OF ARTICLES RESTATED, כפי שמפורסמים באתר האינטרנט של רשות ניירות הערך האמריקאית )SEC )בכתובת:
https://www.sec.gov/Archives/edgar/data/1158780/000117891317000962/exhibit\_3-1.htm https://www.sec.gov/Archives/edgar/data/1158780/000117891314001990/exhibit\_4-1.htm
.6.1 עד השעה 10:00 בבוקר ביום הראשון בו יתקיים מסחר בבורסה לאחר מועד סגירת רשימת החתימות )להלן: "יום הסליקה"(, ימסור רכז ההנפקה למבקשים, באמצעות המורשים לקבלת בקשות, אשר באמצעותם הוגשו הבקשות, הודעה על מידת ההיענות לבקשתם. ההודעה תציין את המחיר שנקבע במכרז, את מספר היחידות שתוקצינה לכל מבקש ואת התמורה שעליו לשלם בגינן.
התמורה הצפויה לחברה מהנפקה זו הינה כמפורט להלן )בהנחה שכל היחידות המוצעות בדוח זה תירכשנה במחיר המזערי ליחידה(.
| טו( וללת )ברו הצפויה כ המיידית התמורה |
ח אלפי ש" 51,300 |
|---|---|
| והפצה ריכוז )עמלת מוערכות הנפקה הוצאות 4 וייעוץ( |
ח אלפי ש" 2,595 |
| וקדמת חייבות מ עמלת הת ו( צפויה )נט תמורה סה"כ |
ח אלפי ש" 1,218 ח אלפי ש" 47,487 |
לפרטים בדבר יעוד תמורת ההנפקה ראו עמ' 3 "Proceeds of Use "לתשקיף המדף האמריקאי המצ"ב כנספח ב' לדוח זה.
4
להוצאות ההנפקה יתווסף מע"מ כדין, ככל שיידרש. לפרוט אודות הוצאות ההנפקה ראה סעיף 9 לדוח הצעת המדף. הסכום הנ"ל אינו משקף עמלת הצלחה ללידר, בהתאם לשיקול דעת החברה, בסך של עד 1% מתמורת ההנפקה )ברוטו(.
הזמנים, כמפורט בסעיף זה מהווה מידע צופה פני עתיד כמשמעותו בחוק ניירות ערך, העשויים להשתנות, בין היתר, כתוצאה משינוי בהיקף הפעילות של החברה והחלטות הדירקטוריון.
עד לשימוש בתמורת ההנפקה, כספי תמורת ההנפקה יוחזקו בחשבונות החברה ויושקעו על ידה בהתאם למדיניות ההשקעות של החברה כפי שתהיה מעת לעת.
לידר הנפקות )1993( בע"מ )"לידר"(, ברק קפיטל חיתום בע"מ, ענבר הנפקות ופיננסים בע"מ, דיסקונט חיתום והנפקות בע"מ, א.ס.ברטמן השקעות בע"מ, אגוז הנפקות ופיננסים בע"מ, אמ.די פרמיום הנפקות בע"מ וי.א.צ השקעות ונכסים בע"מ, ישמשו כמפיצים בהנפקה )להלן: ״המפיצים״(.
החברה התחייבה לשלם עמלות כדלקמן:
)1( עמלת ייעוץ ללידר בשיעור של 3% מתמורת ההנפקה )ברוטו(; )2( עמלת ניהול ללידר בשיעור של 1% מתמורת ההנפקה )ברוטו(; )3( עמלת הפצה למפיצים בשיעור של 1% מתמורת ההנפקה )ברוטו(, אשר תחולק בין המפיצים לפי שיקול דעתה הבלעדי של לידר; )4( עמלת הצלחה ללידר בשיעור של עד 1% מתמורת ההנפקה )ברוטו(, שתשולם על פי שיקול דעתה הבלעדי של החברה; )5( עמלת ריכוז הנפקה לרכז ההנפקה בסך של 30 אלפי ש"ח.
מובהר כי העמלות המפורטות בסעיף זה לא כוללות תשלום עמלה למשקיעים המסווגים כמפורט בסעיף 4.6 לעיל.
לכל הסכומים לעיל יתווסף מע"מ כדין, ככל שיידרש.
הצעת ניירות הערך על פי דוח הצעת המדף אינה מובטחת בחיתום.
התחייבות הדירקטורים כאמור, תעמוד בתוקף כל עוד הדירקטורים ממשיכים לכהן בתפקידם כדירקטורים בחברה.
בהתאם להוראות תקנה 4א' לתקנות ניירות ערך )אגרת בקשה למתן היתר לפרסום תשקיף(, התש״ה,1995- החברה תשלם לרשות ניירות ערך את תוספת האגרה בעד ניירות הערך המוצעים במסגרת דוח הצעת המדף.
לפרטים בדבר שינויים וחידושים מהותיים אשר אירועו בכל עניין שיש לתארו בתשקיף המדף שחלו מיום פרסום תשקיף המדף ועד מועד פרסום דוח הצעת מדף זה, ראה דיווחים שוטפים של החברה המפורסמים באתר האינטרנט של הבורסה בכתובת: il.co.tase.maya.www. דיווחים שוטפים כאמור נכללים בדוח הצעת מדף זה על דרך ההפניה, בהתאם להוראות תקנה 4 )א( לתקנות ניירות ערך )הצעת מדף של ניירות ערך(, תשס"ו- .2005
מכתב הסכמה שניתן לחברה על ידי רואה החשבון המבקר שלה להכללה בדוח הצעת מדף זה, על דרך ההפנייה, את דוחות רואה החשבון המבקר שנחתמו על ידם בתאריך 7 בספטמבר, ,2017 מצ"ב כנספח א' לדו"ח הצעת מדף זה.
Since the price per share of our common stock being offered is higher than the net tangible book value per share of our common stock, you will suffer substantial dilution in the net tangible book value of the common stock you purchase in this offering.
We intend to use the net proceeds from this offering for research and product development activities, clinical trial activities, investment in capital equipment and for working capital and other general corporate purposes. Our management will have significant flexibility in applying the net proceeds of this offering. The actual amounts and timing of expenditures will vary significantly depending on a number of factors, including the amount of cash used in our operations and our research and development efforts. Management's failure to use these funds effectively would have an adverse effect on the value of our common stock and could make it more difficult and costly to raise funds in the future.
We have issued a substantial number of shares issued or issuable upon exercise of warrants and options to purchase our shares that are eligible for, or may become eligible for, unrestricted resale. Any sales or registration of such shares in the public market or otherwise could reduce the prevailing market price for our shares, as well as make future sales of equity securities by us less attractive or even not feasible. The sale of shares issued upon the exercise of our options and warrants, could also further dilute the holdings of our then existing shareholders.
.16 החברה קיבלה את חוות הדעת המשפטית הבאה:

30 באוקטובר 2017
לכבוד פלוריסטם תרפיוטיקס אינק. מרכז תעשיות מדע, בנין 5 חיפה
שלום רב,
לבקשתכם, הרינו לאשר בזה כי:
בהתייחס לתשקיף המדף של החברה מיום 14 בספטמבר 2017 כפי שפורסם ביום 13 בספטמבר 2017 ולדוח הצעת המדף שבנדון, אשר מפורסם מכוחו, הננו לחוות דעתנו כדלקמן:
הרינו מסכימים כי חוות דעתנו זו תיכלל בדו"ח הצעת המדף.
בכבוד רב,
ערן בן דור, עו"ד רעות אלפיה, עו"ד
זיסמן, אהרוני, גייר ושות' עורכי דין
החברה:
__________________________________ פלוריסטם תרפיוטיקס אינק.
הדירקטורים:
_______________________________ זמי אברמן, יו"ר הדירקטוריון
_______________________________ יקי ינאי
_______________________________ נחום רוזמן
_______________________________ דורון שורר
_______________________________ חווה מרצקי
_______________________________ יצחק בראון
_______________________________ ישראל בן יורם
_______________________________ מרק ג'רמיין
_______________________________ מוריה קויאט
קוסט פורר גבאי את קסירר שדרות פל ים ,2 בניין ברוש חיפה 3309502
טל. +972-4-8654000 פקס +972-3-5633433 ey.com

30 באוקטובר, 2017
לכבוד: הדירקטוריון של פלוריסטם תרפיוטיקס אינק. מרכז תעשיות מדע, בנין 5 חיפה
א.ג.נ,
הרינו להודיעכם כי אנו מסכימים להכללה בדרך של הפניה בדו"ח הצעת המדף שבנדון )"דו"ח הצעת המדף"( של החברה את דוח רואה החשבון המבקר המתייחס לדוחות הכספיים המאוחדים של החברה לימים 30 ביוני, 2017 ו2016- ולכל אחת משלוש השנים בתקופה שהסתיימה ביום 30 ביוני, 2017 וכן את דוח רואה החשבון המבקר על ביקורת של רכיבי הבקרה הפנימית על הדיווח הכספי של החברה ליום 30 ביוני ,2017 אשר נחתמו על-ידינו בתאריך 7 בספטמבר, 2017 ונכללו בדוח החברה על גבי טופס K10- אשר הוגש על-ידי החברה ל- Commission Exchange and Securities .S.U ולרשות ניירות ערך בישראל ביום 7 בספטמבר 2017; וכן להכללת שם הפירמה תחת הכותרת "Experts "בתשקיף המדף מיום 14 בספטמבר, .)"Securities Act" -ה :להלן )U.S. Securities Act of 1933 -ב" experts" המונח כמשמעות ,2017
מכתב זה ניתן לפי בקשת החברה ומיועד אך ורק להיכלל בדוח הצעת המדף.
קוסט פורר גבאי את קסירר רואי חשבון

Warrants Units
We may from time to time sell common stock, preferred stock and warrants to purchase common stock, and units of two or more of such securities, in one offerings for an aggregate initial offering price of \$200,000,000. We refer to the common stock, the warrants to purchase common stock and the units collectively as the securities. This prospectus describes the general manner in which our securities may be offered using this prospection with the exercise of certain outstanding warrants, we will specify in an accompanying prospectus supplement the terms of the securities to be offered and sold. We may sell these securities to or through underwriters or dealers, directly to purchasers or through agents. We will set forth the names of any underwriters, dealers or agents in an accompanying prospectus supplement. You should carefully read this prospectus and any accompanying supplements before you decide to invest in any of these securities.
Our common stock is traded on the NASDAQ Capital Market, or Nasdaq, under the symbol "PSTI" and on the Tel Aviv Stock Exchange under the symbol "PLTR."
Neither the Securities and Exchange Commission, or the SEC, nor any state securities commission has approved of these securities or passed upon the adequacy of this prospectus. Any representation to the contrary is a criminal offense.
The date of this prospectus is June 30, 2017.
| ABOUT THIS PROSPECTUS | |
|---|---|
| OUR COMPANY | |
| RISK FACTORS | 2 |
| CAUTIONARY NOTE REGARDING FORWARD-LOOKING INFORMATION | 2 |
| USE OF PROCEEDS | ന |
| THE SECURITIES WE MAY OFFER | ന |
| DESCRIPTION OF CAPITAL STOCK | ന |
| DESCRIPTION OF WARRANTS | ব |
| DESCRIPTION OF UNITS | 6 |
| PLAN OF DISTRIBUTION | 7 |
| VALIDITY OF THE SECURITIES | 10 |
| EXPERTS | 10 |
| WHERE YOU CAN FIND MORE INFORMATION | 10 |
| INCORPORATION OF DOCUMENTS BY REFERENCE | 11 |
You should rely only on the information contained in this prospectus supplement and the documents incorporated by reference herein or therein, or to which we have not authorized anyone to provide you with different information. If anyone provides you with different or inconsistent information, you should not rely on it. This prospectus supplement do not constitute an offer to sell, or a solicitation of an offer to purchase, the securities offered by this prospectus supplement in any jurisdiction to or from any person to whom it is unlawful to make such offer or solicitation of an offer in such jurisdiction. You should not assume that the information contained in this prospectus supplement or any document incorporated by reference is accurate as of any date other than the date indicated in the applicable document.
Neither the delivery of this prospectus nor any distribution of securities pursuant to this prospectus shall, under any circumstances, create any implication that there has been no change in the incorporated by reference into this prospectus or in our affairs since the date of this prospectus. Our business, financial condition, results of operations and prospects may have changed since that date.
Our name and logo and the names of our products are our trademarks. Unless the context otherwise requires, references in this prospectus to "Pluristen" "we," and "our" refer to Pluristem Therapeutics Inc. and its subsidiary as required by the context.
This prospectus is part of a registration statement that we filed with the SEC using a "shelf" registration process. Under this shelf registration process, we may, from time to time, sell any combination of the securities described in this prospectus in one or more offerings up to a total dollar amount of \$200,000. This prospectus describes the securities we may offer and the general manner in which our securities may be offered by this prospectus. Each time we sell securities (other than in connection with the exercise of certain outstanding warrants), we will provide a prospectus supplement that will contain specific information about the terms of that offering. We may also add, update or change in the prospectus supplement any of the information in this prospectus. To the extent there is a conflict between the information contained in this prospectus and the prospectus supplement, you should rely on the information in the prospectus supplement, provided that if any statement in one of these documents is inconsistent with a statement in another document having a later date - for example, a document incorporated by reference in this prospectus or any prospect - the statement in the document having the later date modifies or supersedes the earlier statement.
This summary highlights information contained in the documents incorporated herein by reference. Before making an investment decision, you should read the entire prospectus, and the SEC, including those filings incorporated herein by reference, carefully, including the sections entitled "Risk Factors" and "Cautionary Note Regarding Forward-Looking Statements."
We are a leading developer of placenta-based cell therapy product candidates for the treatment of multiple ischemic, inflammatory and hematologic conditions. Our lead indications are critical limb ischemia, or CLI, recovery for femoral neck fracture, and acute radiation syndrome, or ARS. Pivotal, multinational clinical trials are planned for our PLX-PAD product candidate in CLI and femoral neck fracture, and for our PLX-R18 product candidate in the hematologic component of ARS. Each of these indications is a severe unmet medical need.
PLX cells are derived from a class of placental cells that are harvested from donated placentas at the time of full term delivery of a live baby. PLX cell products require no tissue matching prior to administration. They are produced using our proprietary three-dimension technology. Our manufacturing facility complies with the U.S. Food and Drug Administration's, or FDA's current Good Manufacturing Practice requirements and has been approved by the European. Japanese and Israeli regulation of PLX-PAD for late stage trials and marketing. We expect to have in-house production capacity to grow clinical-grade PLX cells in commercial quantities.
Our goal is to make significant progress with our robust clinical pivotal trials in order to ultimately bring imovative, potent therapies to patients who need new treatment options. We intend to commercialization of our first product candidate, PLX-PAD, by leveraging the unique accelerated regulatory pathways that exist in Europe and Japan to bring innovative products that address life-threatening diseases to the market efficiently. We believe that these accelerated pathways create substantial opportunities for us and for the cell therapy industry as a whole. We are pursuing these accelerated pathways for PLX-PAD in CLI and femoral neck fracture. Our second product candidate, PLX R18, is under development in the United States for ARS via the Animal Rule regult in approval without the prior performance of human efficacy trials. We expect to demonstrate a real-world impact and value from our pipeline, technology platform and commercial-scale manufacturing capacity.
We were incorporated as a Nevada corporation in 2001. We have a wholly owned subsidiary in Israel called Pluristem Ltd. Our executive offices are located at MATAM Advanced Technology Park, Building No. 5, Haifa, Israel, our telephone number is 01 972 74 710 8759 and our website address is www.pluristem.com. This reference to our website is an inactive textual reference only, and is not a hornation on our website is not incorporated by reference in this prospectus and should not be part of this prospectus. You should not consider the contents of our website in making an investment decision with respect to the securities.
1
An investment in our securities involves significant risks. You should carefully consider the risk factors contained in any prospectus supplement and in our filings with the SEC, including our Annual Report on Form 10-K for the fiscal year ended June 30, 2016 as well as all of the information in this prospectus, any prospectus supplement and the other documents incorporated by reference herein or therein, before you decide to invest in our business, prospects, financial condition and results of operations may be materially and adversely affected as a result of any of such risks. The value of our securities could decline as a result of any of these risks. You could lose all or part of your investment in our securities we have described are not the only ones we face. Additional risks and uncertainties not presently known to us or that we currently deem immaterial may also affect our business, prospects, financial condition and results of operations.
We have signed a binding term sheet with Innovative Medical Management Co. Ltd., or Innovative Medical, related to Imnovative Medical's proposed investment of approximately \$30,000,000. Although that definitive agreements would be executed by December 26, 2016, we announced on December 23, 2016, that, due to a recently adopted Chinese policy relating to outbound investments by Chinese companies, we agreed to extend the time of execution of the definitive agreements relating to Innovative Medical's proposed investment. As a result of this recently adopted Chinese policy, we now plan to continue the discussions with respect to the definitive agreements until we have received further clarification about such we initially expected to receive during the first half of 2017. We now do not expect the needed clarifications regarding the agreement with Innovative Medical to be provided by the first half of 2017. Thus, it is possible that the definitive agreements will not be executed on terms and conditions that are materially different than those set forth in the term sheet. There can be no assurance the definitive agreements or that Innovative Medical's proposed investment will be made.
We have signed a binding term sheet with Sosei Corporate Venture Capital Ltd., or Sosei CVC, for the establishment of for the establishment of a new Japanese corporation, or NewCo, for the clinical development and commercialization of our PLX-PAD cell therapy product in Japan. While the parties have executed a term sheet and definitive agreements will be finalized in the coming months, there is no guarantee that we will be successful in executing agreements by then. It is possible that the definitive agreements will not bey may be executed on terms and conditions that are materially different than those set forth in the term sheet. That we will execute the definitive agreements or that the proposed joint venture with Sosei CVC will be completed.
The statements contained in this prospectus supplement and the documents we incorporate by reference herein or therein that are not historical facts are "forward-looking statements" within the meaning of the Privation Reform Act of 1995 and other federal securities laws. Such forward-looking statements may be identified by, among other things, the use of forward-looking terminology such as "believes," "intends," "plans," "may," "will," "should," or "anticipates" or the negative thereon or comparable terminology, and similar expressions are intentify forward-looking statements. We remind readers that forward-looking statements are merely predictions and therently subject to uncertainties and other factors and involve known risks that could cause the actual results, performance, levels, or our achievements, or industry results, to be materially different from any future results, performance, levels of activity, achievements or inplied by such forward-looking statements. The factors discussed herein, including those risks described under the heading "Risk Factors" herein and in the corporate by reference, as well as those discussed elsewhere in this prospectus supplement could cause actual results and developments to be materially different from those expressed in or internents. In addition, historic results of scientific research, clinical and preclinical trials do not guarantee that the conclusions of future research or trials would not suggest different conclusions. Also, historic reserved to this prospectus, any prospectus supplements we incorporate by reference may be interpreted differently in light of additional research, clinical and preclinical trials results. Except as required by law we undertake no oblicly update such forward-looking statements to reflect subsequent events or circumstances.
Unless we otherwise indicate in an applicable prospectus supplement, we currently intend to use the net of the securities for research and product development activities, investment in capital equipment and for working capital and other general corporate purposes.
We may set forth additional information on the use of net proceeds from the sale of securities we offer under this prospectus in a prospectus supplement relating to the specific of the application of the net proceeds, we intend to invest any proceeds in a variety of capital preservation instruments such as bank deposits or invest-bearing securities subject to any investment policies our investment committee may determine from time to time.
The descriptions of the securities contained in this prospectus, together with any applicable prospectus supplement, summarize the material terms and provisions of the various types of securities that we may offer. We will describe in any applicable prospectus supplent relaing to any securities the particular terms of the securities offered by that prospectus supplied in any applicable prospectus supplement, the terms of the securities may differ from the terms we have summarized below. We may prospectus supplement information, where applicable, about material U.S. federal income tax consequences relating to the securities exchange or market, if any, on which the securities will be listed.
We may sell from time to time, in one or more offerings, one or more of the following securities:
The total initial offering price of all securities that we may issue in these offerings will not exceed \$200,000,000.
Our authorized capital stock currently consists of 200,000,000 shares of common stock, of which there were 96,171,868 shares outstanding as of March 31, 2017, and 10,000,000 shares of "blank check" preferred stock, none of which are outstanding. The following statements set forth the material terms of our capital stock; however, reference is made to the more detailed provisions of, and these statements are qualified in their entirety by reference to, our Articles of Incorporation and Bylaws, copies of which are in, and the provisions of Nevada General Corporation Law. Except for our additional securities, including preferred stock with terms that may be determined at a later date by our Board, there are no provision or Bylaws that would delay, defe or prevent a change in our control.
Except as otherwise required by applicable law and subject to the preferential rights of any outstanding preferred stock, all voting rights are vested in and exercised by the holders of common stock with each share of our common stock being entitled to one vote. In the event of liquidation, holders of the common stock are entitled to share ratably in the distribution of assets remaining after payment of liabilities, if any. Holders of the common stock have no cumulative voting rights and no preemptive or other rights to subscribe for shares. Holders of common stock are entitled to such dividends as may be declared by the Board of funds legally available therefor.
Our Board of Directors is empowered, without further action by stockholders, to issue from time to time one or more series of preferred stock, with such designations, rights, preferences and limitations as the Board may determine by resolution. The rights, preferences and limitations of separate series of preferred stock may differ with respect to such matters as may be determined by the Board, including, without limitation, the rate of dividends, method and nature of payment of cividends, terms of redemption, sinking fund provisions (if any), conversion rights. Certain issuances of preferred stock may have the effect of delaying or preventing a change in control of our company that some stockholders may believe is not in their interest.
American Stock Transfer and Trust Company, LLC is the registrar and transfer agent for our common shares. Their address is 620 15th Avenue, 2nd Floor, Brooklyn, NY 11219, telephone: (718) 921-8261, (800) 937-5449.
Nevada revised statutes sections 78.378 to 78.3793 provide state regulation of a controlling interest in certain Nevada corporations unless the articles of incorporation provide that the provisions of these sections do not apply. This statute currently does not apply to our Company because we would have to have as shareholders a specified number of Nevada residents and we would have to do business in Nevada directly or through an affiliate.
The following description, together with the additional include in any applicable prospectus supplement, summarizes the material terms and provisions of the warrants that we may offer under this prospectus and the related warrant certificates. While the terms summarized below will apply generally to any offer, we will describe the particular terms of any series of warrants (and any securities issuable upon execcise of such warrants) in more detail in the so indicate in a prospectus supplement, the terms of any warants offered under that prospectus supplement may differ from the describe below. Specific warrant agreements will contant terms and provisions and will be incorporated by reference as an exhibit to the registration statement.
We may issue warrants for the purchase of common stock in one or more series. We may issue warrants independently or together with common stock, and the warrants may be attached to or separate from the common stock.
We will evidence each series of warrant certificates that we will issue under a separate agreement or by warrants that we will enter into directly with the warrants. If we evidence warrants by warrant certificates, we will enter into a warrant agreement with a warrant agent. We will indicate the narrant agent, if any, in the applicable prospectus supplement relating to a particular series of warrants.
We will describe in the applicable prospectus supplement the terms of the series of warrants, including:
Before exercising their warrants, holders of warrants will not have any of the common stock purchasable upon such exercise, including the right to receive dividation, if solution or winding or winding up or to execuse voing rights, if any.
Each warrant will entitle the holder to purchase of common stock that we specify in the applicable prospectus supplement at the exercise price that we describe in the applicable prospectus supplement. Unless we otherwise specify in the applicable prospectus supplement, holders of the warrants may exercise the warrants at any time up to 5:00 P.M., Eastern U.S. time, on the expiration date that we set forth in the applicable prospectus supplement. After the expiration date, unexercised warrants will become void.
Holders of the warrants may exercise the warrant agent or us the warrant certificate or warrant agreement representing the warrants to be exercised together with specified information, and by paying the required amount to the warrant agent or us in immediately available funds, as provided in the applement. We will set forth on the reverse side of the warrant certificate or in the warrant agreement and in the applement the information that the holder of the warrant will be required to deliver to the warrant agent or us in connection with such exercise.
Upon receipt of the required payment and the warrant certificate or the warrant as applicable, properly completed and duly executed at the corporate trust office of the warrant agent, if any, at our office indicated in the applicable prospectus supplement, we will issue and deliver the common stock or other securities purchasable upon such exercise. If fewer than all of the warrants represented by the warrant certificate or warrant are exercised, then we will issue a new warrant certificate or warrant agreement for the remaining amount of warrants.
If we appoint a warrant agent , any warrant agent will act solely as our agent under the applicable warrant and will not assume any obligation or relationship of agency or trust with any warrant. A single bank or trust company may act as warrant agent for more than one issue of warrants. A warrant agent will have no duty or responsibility in case of any default by us under the applicable warrant agreement or warrant, including any duty or responsibility to intiate any proceedings at to make any demand upon us. Any holder of a warrant may, without the consent of the related warrant agent or the holder of any other warrant, enforce by appropriate legal action its right to exercise, and receive the securities purchasable upon exercise of, its warrants.
The shares of common stock registered under the registration statement of which this prospectus is a part include 3,219,983 shares of common stock issuable upon exercise of warrants that were registration statement on Form S-3 declared effective on October 20, 2011 (Registration No. 333-177009). Such warrants were issued on September 19, 2012, have an exercise price of expire on September 19, 2017.
No prospectus supplement will be delivered in connection with the issuance of common stock pursuant to the exercise of such warrants.
We may issue, in one or more series, units consisting of common stock, preferred stock and/or warrants for the purchase of common stock and or preferred stock, in any combination. While the terms we have summarized below will apply generally to any offer under this prospectus, we will describe the particular terms of units in more detail in the applicable prospectus supplement. The terms of any units offered under a prospectus supplement may differ from the terms described below.
We will file as exhibits to a prospectus supplement, or will incorporate by reference from reports that we file with the SEC, the form of unit agreement that describes the terms of the series of units we are offering, and any supplemental agreements, before the related series of units. The following summarial terms and provisions of the units are subject to, and qualified in their entirety by reference to, all the provisions of the unit agreement and any supplements applicable to a particular series of units. We urge you to read the applicable prospectus supplement related to the particular series of units that we may offer under this prospectus and the complete unit agreement and any supplemental agreements that contain the terms of the units.
Each unit will be issued so that the holder of the unit is also the holder of each security included in the unit. Thus, the holder of a unit will have the rights and obligations of a holded security. The unit agreement under which a unit is issued may provide that the securities included in the unit may not be held or transferred separately, at any time before a specified date.
We will describe in the applicable prospectus supplement the terms of the series of units, including:
The provisions described in this section, as well as those described under "Description of Warrants" will apply to each unit and to any common stock, preferred stock or warrant included in each unit, respectively.
We may issue units in such amounts and in such distinct series as we determine.
We may sell the securities being offered hereby in one or more of the following ways from time to time:
The securities that we distribute by any of these methods may be sold, in one or more transactions, at:
The accompanying prospectus supplement will describe the terms of our securities, including:
If underwriters are used in the sale, they will acquire the securities for their own account and may resell the in one or more transactions, including negotiated transactions, at a fixed public offering prices determined at the time of the sale. The obligations of the underwriters to purchase the securities will be subject to the applicable underwriting agreement. We may offer the securities to the public through underwriting syndicates represented by managing underwriters without a syndicate. Subject to certain conditions, the underwriters will be securites offered by the prospectus supplement. We may change from time to time the public offering price and any discounts or concessions allowed or paid to dealers.
If we use a dealer in the sale of the securities being offered pursuant to this prospectus supplement, we will sell the securities to the dealer, as principal. The securities to the public at varying prices to be determined by the dealer at the time of resale. The names of the dealers and the terms of the transaction will be specified in a prospectus supplement.
We may sell the securities directly or through agents we designate from time. We will name any agent involved in the offering and sale of securities and we will describe any commissions we will pay the agent in the prospectus supplement states otherwise, any agent will act on a best-efforts basis for the period of its appointment.
We may also sell securities pursuant to an "equity line of credit". In such event, we will enter into a common stock purchase agreement with the purchaser to be named therein, which will be described in a Current Report on Form 8-K that Form 8-K, we will describe the total amount of securities that we may require the purchase under the purchase agreement and the other terms of purchase, and any rights that the purchase securities from us. In addition to our issuance of shares of common stock to the equity line purchaser pursuant to the purchase agreement, this prospectus supplicable prospectus supplement or post-effective amendment) also covers the resale of those shares from time by the equity line purchaser to the public. The equity line purchaser will be considered an "underwriter" within the meaning of Section 2(a)(11) of the Securities Act. Its resales may be effected through a number of methods, including without limitation, ordinary brokerage transactions in which the broker solicits purchasers and block trades in which the broker or dealer so engaged will attempt to sell the shares as agent, but may position of the block as principal to facilitate the transaction. The equity line purchaser will be bound by various anti-manipulation rules of the SEC and may not, for example, engage in any stabilization activity in connection with its resales of our securities and may not bid for or attempt to induce any person to purchase any of our securities other than as permitted under the Securities Exchange Act of 1934, as amended, or the Exchange Act.
We may sell our securities directly or through agents we designate from time. We will name any agent involved in the offering and sale of our common stock, and we will describe any commissions we will pay the agent in the prospectus supplement states otherwise, our agent will act on a best-efforts basis for the period of its appointment.
We may provide underwriters and agents with indemnification against civil liabilities related to offerings pursuant to this prospectus, including liabilities under the Securities with respect to payments that the underwriters or agents may make with respect to these liabilities. Underwriters and agents may encrease with, or perform services for, us in the ordinary course of business. We will describe such relationships in the prospectus supplement naming the underwriter or agent and the nature of any such relationship.
Rules of the SEC may limit the ability of any underwriters to bid for or purchase securities before the distribution of the shares of common stock is completed. However, underwriters may engage in the following activities in accordance with the rules:
Similar to other purchase transactions, an underwriter's purchases to cover the syndicate short stabilize the market price of our common stock may have the effect of raising the market price of our common stock or preventing or mitigating a decline in the market price of our common stock. As a result, the shares of our common stock may be higher than the price that might otherwise exst in the open market. The imposition of a penalty bid might also have an effect on the price of shares.
If commenced, the underwriters may discontinue any of these activities at any time.
Our common stock is traded on the NASDAQ Capital Market and on the Tel Aviv Stock Exchange. One or more underwriters may make a market in our common stock, but the underwriters will not be obligated to do so and may discontinue market make . We cannot give any assurance as to liquidity of the trading market for our common stock.
Any underwriters who are qualified market makers on the NASDAQ Capital Market may engage in passive market making transactions in that market in the common stock in accordance with Rule 103 of Regulation M, during the business day prior to the offering, before the commencement of offers or sales of the common stock. Passive market makers must comply with applicable volume and must be identified as passive market maker market maker must display its bid at a price not in excess of the highest independent bid for such security; if all independent bids are lowered below the passive market maket maket maket maket maket maket maket maket maket maket maket maket maket bid must then be lowered when certain purchase limits are exceeded.

In compliance with guidelines of the Financial Industry Authority, or FINRA, the maximum commission or discount to be received by any FINRA member or independent broker dealer may not exceed 8% of the securities offered pursuant to this prospectus and any applicable prospectus supplement.
We will sell and deliver shares of our common stock directly to those holdly exercise certain warrants that were registered under a previous registration statement. No prospectus supplement with such transactions. See "Description of Warrants - Outstanding Warrants" on page 5 of this prospectus.
Zysman, Aharoni, Gayer and Sullivan & Worcester LLP, New York, passed upon the validity of the securities offered hereby.
The consolidated financial statements of Pluristem Therapeutics Inc. appearing in Form 10-K for the fiscal year ended June 30, 2016 and the effectiveness of the internal control over financial reporting of Pluristem Therapentics Inc. as of June 30, 2016, have been audited by Kost Forer Gabbay & Kasier, a member of Ernst & Young Global, independent registered public accounting firm, as set forth in their reports thereon, included therein by reference. Such consolidated financial statements are incorporated herein by reference in reliance upon such reports given on the authority of such firm as experts in accounting and auditing.
We are subject to the reporting and information requirements of the Exchange Act and as a result file periodic reports and other information with the SEC. These periodic reports and other inspection and copying at the SEC's public reference room and the website of the SEC referred to below.
We have filed a registration statement on Form S-3 under the Securities Act with respect to the shares of our common stock, warrants, preferred stock and units offered through this prospectus is filed as a part of that registration statement and does not contain all of the information contained in the registration statement and exhibits. We registration statement and each exhibit attached to it for a more complete description of may us, and the statements we have made in this prospectus are qualified in their entirety by reference to these additional materials.
You may read and copy the reports and other information we file with the SEC's Public Reference Room at 100 F Street, N.E., Washington D.C. 20549. You may also obtain copies of this information by mail from the public reference section of the SEC, 100 F Street, N.E., Washington, D.C. 20549, at prescribed rates. You may obtain information regarding the public reference room by calling the SEC at 1 (800) SEC-0330. The SEC also maintains reports and other information about issuess, like us, who file electronically with the SEC. The address of that website is http://www.sec.gov. This reference to the SEC's website is an inactive textual reference only, and is not a hyperlink.

We are "incorporating by reference" certain documents we file with the SEC, which means that we can disclose important information to you by referring you to those documents. The information in the documents incorporated by reference is considered to be part of this prospectus. Statements contained in documents that we file the SEC and that are incorporated by reference in this prospectus will automatically undate and supersede information contained in this prospectus, including information in previously filed documents or reports that have been incorporated by reference in this prospectus, to the new information differs from or is inconsistent with the old information.
We have filed or may file the following documents with the SEC. These documents are incorporated herein by reference as of their respective dates of filing:
(a) Our Annual Report on Form 10-K for the year ended June 30, 2016 filed with the SEC on September 7, 2016;
Our Quarterly Reports on Form 10-Q for the quarters ended September 31, 2016 and March 31, 2017, as (b) filed with the SEC on November 7, 2016, February 8, 2017 and May 8, 2017, respectively:
Our Current Reports on Form 8-K filed with the SEC on October 10, 2016, December 20, 2016, December 23, (c) 2016, January 11, 2017, January 20, 2017, March 29, 2017, March 30, 2017, May 25, 2017, May 25, 2017, June 20, 2017 and June 23, 2017; and
The description of our common stock contained in the Registration Statement on Form 8-A filed on December 10, 2007, under (d) the Exchange Act, including any amendment or report filed or to be filed for the purpose of updating such description.
All documents filed by us pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act until all of the securities to which this prospectus relates has been sold or the offering is otherwise terminated, except in each case for information contained in any such filing where we indicate that such information is being furnished and is not to be considered "filed" under the Exchange Act, will be deemed to be incorporated by reference in this prospectus and any accompanying prospectus supplement and to be a part hereof from the date of filing of such documents.
We will provide a copy of the documents we incorporate by reference, at no cost, to any person who receives this prospectus. To request a copy of any or all of these documents, you should write or telephone us at MATAM Advanced Technology Park, Building No. 5, Haifa, LS 31905, Israel, Attention: Erez Egozi.
11

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