Pluri Inc. — Director's Dealing 2016

Jan 7, 2016

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Check this box if no longer subject to Section 16. Form 4 STATEMENT OF CHANGES IN BENEFICIAL or Form 5 obligations may continue. See Instruction 1 OWNERSHIP (b).

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person[*] 2. Issuer Name and Ticker or Trading Symbol 5. Relationship of Reporting Person(s) to Issuer PLURISTEM THERAPEUTICS (Check all applicable)

GERMAIN MARK 0001195498 INC [ PSTI ] X Director 10% Owner Officer (give title Other (specify

(Last) (First) (Middle) below) below)

(Last) (First) (Middle) below) below) 3. Date of Earliest Transaction (Month/Day/Year) 133 CLINTON STREET 01/05/2016 (Street) 4. If Amendment, Date of Original Filed 6. Individual or Joint/Group Filing (Check (Month/Day/Year) Applicable Line) BROOKLYN NY 11201 X Form filed by One Reporting Person Form filed by More than One Reporting (City) (State) (Zip) Person Table I – Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1. Title of Security (Instr. 3) 2. Transaction 2A. Deemed 3. 4. Securities Acquired (A) 5. Amount of 6. 7. Nature Date Execution Date, if Transaction or Disposed Of (D) (Instr. Securities Ownership of Indirect (Month/Day/Year) any Code (Instr. 3, 4 and 5) Beneficially Form: Beneficial (Month/Day/Year) 8) Owned Direct (D) or Ownership Following Indirect (I) (Instr. 4) (A) Reported (Instr. 4) Code V Amount or Price Transaction(s) (D) (Instr. 3 and 4) Common Stock 01/05/2016[(1)] A 48,000 A $0 387,135 D Table II – Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities) 1. Title of 2. 3. Transaction 3A. Deemed 4. 5. 6. Date Exercisable and 7. Title and 8. Price 9. Number 10. 11. Nature Derivative Conversion Date Execution Date, if Transaction Number Expiration Date Amount of of of Ownership of Indirect Security or Exercise (Month/Day/Year) any Code (Instr. of (Month/Day/Year) Securities Derivative Derivative Form: Beneficial (Instr. 3) Price of (Month/Day/Year) 8) Derivative Underlying Security Securities Direct (D) Ownership Derivative Securities Derivative (Instr. 5) Beneficially or Indirect (Instr. 4) Security Acquired Security (Instr. Owned (I) (Instr. (A) or 3 and 4) Following 4) Disposed Reported of (D) Transaction (Instr. 3, (s) (Instr. 4) 4 and 5) Amount or Number Date Expiration of Code V (A) (D) Exercisable Date Title Shares

Explanation of Responses:

1. The shares vest as follows: 25% after 6 months from grant and the remaining shares vest in 6 equal installments every 3 months thereafter. Remarks:

/s/ Mark Germain 01/07/2016 ** Signature of Reporting Person Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

• If the form is filed by more than one reporting person, see Instruction 4(b)(v).

• ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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