Pluri Inc. — Director's Dealing 2016

Feb 17, 2016

FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Check this box if no longer subject to Section 16. Form 4 STATEMENT OF CHANGES IN BENEFICIAL or Form 5 obligations may continue. See Instruction 1 OWNERSHIP (b).

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Issuer Name and Ticker or Trading Symbol 5. Relationship of Reporting Person(s) to Issuer PLURISTEM THERAPEUTICS (Check all applicable)

INC [ PSTI ] X Director 10% Owner X Officer (give title Other (specify below) below)

1. Name and Address of Reporting Person[*] YANAY YAKY 0001402539

(Last) (First) (Middle) below) below) 3. Date of Earliest Transaction (Month/Day/Year) 14 ARGAMAN ST. 02/16/2016 CFO, COO & President (Street) 4. If Amendment, Date of Original Filed 6. Individual or Joint/Group Filing (Check (Month/Day/Year) Applicable Line) SHIMSHIT L3 17906 X Form filed by One Reporting Person Form filed by More than One Reporting (City) (State) (Zip) Person Table I – Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1. Title of Security (Instr. 3) 2. Transaction 2A. Deemed 3. 4. Securities Acquired 5. Amount of 6. 7. Nature of Date Execution Date, if Transaction (A) or Disposed Of (D) Securities Ownership Indirect (Month/Day/Year) any Code (Instr. (Instr. 3, 4 and 5) Beneficially Form: Beneficial (Month/Day/Year) 8) Owned Direct (D) Ownership Following or Indirect (Instr. 4) Reported (I) (Instr. 4) (A) Transaction Code V Amount or Price (s) (Instr. 3 (D) and 4) Common Stock 1,451,616 D By Yaacov Common Stock 02/16/2016 P 7,500 A $0.83 53,999 I Yanay Management Ltd. By Yaacov Common Stock 02/16/2016 P 7,500 A $1.07 61,499 I Yanay Management Ltd.

Table II – Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of 2. 3. Transaction 3A. Deemed 4. 5. 6. Date Exercisable and 7. Title and 8. Price 9. Number 10. 11. Nature Derivative Conversion Date Execution Date, if Transaction Number Expiration Date Amount of of of Ownership of Indirect Security or Exercise (Month/Day/Year) any Code (Instr. of (Month/Day/Year) Securities Derivative Derivative Form: Beneficial (Instr. 3) Price of (Month/Day/Year) 8) Derivative Underlying Security Securities Direct (D) Ownership Derivative Securities Derivative (Instr. 5) Beneficially or Indirect (Instr. 4) Security Acquired Security (Instr. Owned (I) (Instr. (A) or 3 and 4) Following 4) Disposed Reported of (D) Transaction (Instr. 3, (s) (Instr. 4) 4 and 5) Amount or Number Date Expiration of Code V (A) (D) Exercisable Date Title Shares Explanation of Responses: Remarks:

/s/ Yaky Yanay 02/17/2016 Date

** Signature of Reporting Person

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