Pluri Inc.

Major Shareholding Notification • Jun 23, 2017

Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549 Check this box if no longer subject to

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number: 3235-0287 Estimated average burden hours 0.5 per response

* 1. Name and Address of Reporting Person YANAY YAKY 0001402539			2. Issuer Name and Ticker or Trading Symbol PLUR ISTEM THERAPEUTICS INC [ PSTI ]	5. (Check	Relationship of Reporting Person(s) to Issuer all applicable)
(Last) 14 ARGAMAN	(First) (Middle) ST.		3. Date of Earliest Transaction (Month/Day/Year) 06/21/2017	X X	Director Officer (give title below) Co-CEO &	10% Owner Other (specify below) President
(Street) SHIMSHIT	L3	17906	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual X	or Joint/Group Filing (Check Form filed by One Reporting Form filed by More than One	Applicable Line) Person Reporting Person
(City)	(State)	(Zip)

Table I – Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned	6. Ownership Form: Direct (D) or Indirect	7. Nature of Indirect Beneficial
		any (Month/Day/Year)	Code V		Amount (A) or (D)		Price	Following Reported Transaction(s) (Instr. 3	(I) (Instr. 4)	Ownership (Instr. 4)
	and 4)
Common Stock	(1) 06/21/2017		A		2,000,000	A	\$0	3,651,616	D
Common Stock								66,499	I	By Yaacov Yanay Management Ltd.

Table II – Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of 2. Derivative Conversion Date Security (Instr. 3) or Exercise Price of Derivative Security		3. Transaction (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)		4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4	6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares		Transaction(s) (Instr. 4)

Explanation of Responses:

1. The shares vest as follows: 12.5% on the 6 month anniversary of the date of grant and the remaining shares vest in 14 equal installments every 3 months thereafter. Remarks:

/s/ Yaky Yanay 06/23/2017

** Signature of Reporting Person Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.