PHYSIOMICS PLC — Share Issue/Capital Change 2015

Mar 26, 2015

National Storage Mechanism | Additional information

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RNS Number : 4872I

Physiomics PLC

26 March 2015

Physiomics plc

(the "Company" or "Physiomics")

Issue of Options

The Company confirms that it has agreed to issue share options to each of its directors, as follows:

·     32,261,553 share options over ordinary shares in the Company ("Share Options") have been granted to each of Mark Chadwick and Christophe Chassagnole under the Enterprise Management Initiative Scheme ("EMI"). The options are exercisable at a price of 0.062p each (being the average mid-market closing price for the three days prior to the date of issue); and

·     12,904,621 share options over ordinary shares in the Company ("Share Options") have now been granted to Paul Harper under an Unapproved Share Option Scheme. The options are exercisable at a price of 0.062p each.

The options vest after 6 months and can be exercised within 10 years of the date of grant.

If all the new Share Options granted were to the directors were to be exercised, they would represent 3.12% of the current issued share capital of the Company.

Following this issue, Mark Chadwick and Christophe Chassagnole will each hold 73,413,426 share options and Paul Harper will hold 29,365,370 share options over ordinary shares in the Company in accordance with the table below.

		Share Options
	Award no.	Granted	Exercise price		Expiry date
				(p)
Paul Harper	1	2,327,710		0.15		18-Dec-18
	2	7,664,541		0.40		28-Feb-20
	3	1,293,250		0.34		08-Nov-21
	4	5,175,248		0.132		11-Feb-23
	5	12,904,621		0.062		23-Mar-25
Christophe Chassagnole	1	7,499,453		0.383		06-Sep-17
	2	5,624,590		0.15		18-Dec-18
	3	11,856,584		0.40		28-Feb-20
	4	3,233,125		0.34		08-Nov-21
	5	12,938,121		0.132		11-Feb-23
	6	32,261,553		0.062		23-Mar-25
Mark Chadwick	1	19,984,500		0.27		05-Dec-20
	2	3,233,127		0.34		08-Nov-21
	3	4,996,125		0.293		18-Dec-21
	4	12,938,121		0.132		11-Feb 23
	5	32,261,553		0.062		23-Mar-25

ENDS

Enquiries:

Physiomics plc                                                  

Mark Chadwick 

+44 (0)1865 784980

WH Ireland Limited

Katy Mitchell

+44 (0) 161 832 2174

About Physiomics plc

Physiomics (AIM:PYC) is a computational systems biology services company applying simulations of cell behaviour to drug development to reduce the high attrition rates of clinical trials. 80-90 per cent of all clinical drug candidates fail to reach the market and estimates show that an overall ten per cent improvement in success rates could reduce the cost of one drug's development by as much as $242 million, from the current estimate of around $800 million1.

Physiomics develops computational systems biology models to predict and understand cancer drug efficacy from pre-clinical research to clinical development. Physiomics has created detailed mathematical models incorporating the most important molecular events taking place during the human cell cycle and apoptosis processes. The company's SystemCell® technology enables the simulation of populations of "virtual cells". The company has also developed a "Virtual Tumour" model to simulate the effect of anti-cancer drugs on tumour growth. The models are used to optimise compound design and to design drug schedules and combination therapies.

Physiomics, based in Oxford, UK, was founded in 2001, and floated on AIM in 2004. For further information, please visit www.physiomics-plc.com

SystemCell® is a registered trademark of Physiomics plc

1Tufts Centre Impact Report 2002

This information is provided by RNS

The company news service from the London Stock Exchange

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