Photocure ASA

Major Shareholding Notification • Apr 11, 2023

Franklin Resources, Inc. One Franklin Parkway San Mateo, CA 94403-1906

tel 650/312.2000 franklintempleton.com

05 April 2023

To: Oslo Børs Market Administration Box 460 Sentrum 0105 Oslo, Norway ma@oslobors.no

Cc: Photocure ASA Hoffsveien 4 0275 Oslo, Norway IR@photocure.com

Dear Sir/Madam:

We are acting on behalf of Franklin Resources, Inc., and its affiliates. Franklin Resources, Inc., a diversified financial services company, and its affiliates perform investment management, advisory and related services for clients on a global basis.

Franklin Resources, Inc. itself does not own any shares of the company; rather the shareholdings are beneficially held by a group of funds and managed accounts that are managed by investment advisers directly or indirectly owned by Franklin Resources, Inc.

Franklin Resources, Inc., on behalf of Templeton Investment Counsel, LLC ("TICLLC"), acting in the capacity as discretionary investment manager to underlying funds and managed accounts hereby gives notice that due to disposal of shares, TICLLC's shareholdings in Photocure ASA, as of 04 April 2023, has decreased below the 5% threshold to 4.688% of issued shares and votes, which totals to 1,271,579 shares. For purposes of this Notification, an outstanding share figure of 27,120,820 shares was used to calculate the percentage.

TICLLC will monitor the performance of the shares in Photocure ASA and may determine either to acquire or dispose of shares in Photocure ASA or otherwise maintain its position on behalf of its discretionary investment management clients (being both funds and individually managed account clients) in the foreseeable future in accordance with the best interests of those clients. The underlying funds and managed accounts managed by TICLLC do not hold any rights to shares in Photocure ASA.

As the shares are publicly traded, they are sold in the secondary market at the then prevailing market price.

Should you require additional information regarding this notification, please contact me via email at subsshholder@franklintempleton.com.

Best Regards,

Cathy Johnson Franklin Resources, Inc. Manager Global Securities – Regulatory Reporting