Pharming Group N.V.

Share Issue/Capital Change • Jun 30, 2009

PHARMING GIVES UPDATE ON OUTSTANDING NUMBER OF SHARES

Leiden, The Netherlands, June 30, 2009. Biotech company Pharming Group NV ("Pharming") (NYSE Euronext: PHARM) today provided an update on its outstanding number of shares following a transaction with YA Global Master SPV LTD ("YA Global").

Under the Standby Equity Distribution Agreement with YA Global, Pharming issued 1,158,011 ordinary shares for a cash consideration of € 0.6 million. As a result of the above transactions, Pharming's total number of outstanding ordinary shares is currently 112,362,987 shares.

About Pharming Group NV

Pharming Group NV is developing innovative products for the treatment of genetic disorders, ageing diseases, specialty products for surgical indications, intermediates for various applications and nutritional products. Pharming has two products in late stage development - Rhucin® for Hereditary Angioedema and human Lactoferrin for use in food products and one product in early stage clinical development - Prodarsan® for Cockayne Syndrome. The advanced technologies of the Company include innovative platforms for the production of protein therapeutics, technology and processes for the purification and formulation of these products, as well as technology in the field of DNA repair (via DNage). Additional information is available on the Pharming website, http://www.pharming.com.

This press release contains forward looking statements that involve known and unknown risks, uncertainties and other factors, which may cause the actual results, performance or achievements of the Company to be materially different from the results, performance or achievements expressed or implied by these forward looking statements.

Contact:

Sijmen de Vries, Pharming Group NV, T: +31 (0)71 52 47 400