Strategic Partners A/S — Director's Dealing 2020

Mar 11, 2020

ORPHAZYME

Company announcement

No. 26/2020

Orphazyme A/S

Ole Maaloes Vej 3

DK-2200 Copenhagen N

www.orphazyme.com

Company Registration No. 32266355

Reporting of transactions in Orphazyme's shares made by persons discharging managerial responsibilities

Copenhagen, Denmark, March 11, 2020 – Pursuant to the Market Abuse Regulation article 19, Orphazyme A/S, CVR no. 32266355 ("Orphazyme"), hereby notifies receipt of information of the following transactions in Orphazyme's shares by persons discharging managerial responsibilities in Orphazyme:

1	Details of the Reporting Person / Closely Associated Person
a)	Name
2	Reason for the notification
a)	Position/status
b)	Initial notification/Amendment
3	Details of the Company, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name
b)	LEI code
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument and identification code
b)	Nature of the transaction
c)	Price(s) and volume(s)
DKK	100.75
DKK	100.75
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00
DKK	101.00

---

ORPHAZYME

			DKK	101.00	138
			DKK	101.00	2,500
			DKK	101.00	69
			DKK	101.00	240
			DKK	101.00	20
			DKK	101.00	137
			DKK	101.00	200
			DKK	101.00	250
			DKK	101.00	4,000
			DKK	101.00	200
			DKK	101.00	4,416
			DKK	101.00	3,182
			DKK	101.00	250
			DKK	101.00	69
			DKK	101.50	140
			DKK	102.00	140
d)	Aggregated information	Aggregated volume: 40,000
Aggregated price: DKK 4,039,986.50
Price per share (volume weighted average): DKK 100.9996625
e)	Date of the transaction	11 March 2020 between 12:12 and 14:10 UTC
f)	Place of the transaction	Nasdaq Copenhagen A/S - XCSE and DCSE

For additional information, please contact

Orphazyme A/S

Anders Vadsholt, CFO

+45 28 98 90 55

About Orphazyme A/S

Orphazyme is a biopharmaceutical company focused on bringing novel treatments to patients living with life-threatening or debilitating rare diseases. Our research focuses on developing therapies for diseases caused by misfolding of proteins, including lysosomal storage diseases. Arimoclomol, the company's lead candidate, is in clinical development for four orphan diseases: Niemann-Pick disease Type C, Gaucher disease, sporadic Inclusion Body Myositis, and Amyotrophic Lateral Sclerosis. The Denmark-based company is listed on Nasdaq Copenhagen (ORPHA.CO). For more information, please visit www.orphazyme.com.

Forward-looking statement

This company announcement may contain certain forward-looking statements. Although the Company believes its expectations are based on reasonable assumptions, all statements other than statements of historical fact included in this company announcement about future events are subject to (i) change without notice and (ii) factors beyond the Company's control. These statements may include, without limitation, any statements preceded by, followed by, or including words such as "target," "believe," "expect," "aim," "intend," "may," "anticipate," "estimate," "plan," "project," "will," "can have," "likely," "should," "would," "could", and other words and terms of similar meaning or the negative thereof. Forward-looking statements are subject to inherent risks and uncertainties beyond the Company's control that could cause the Company's actual results, performance, or achievements to be materially different from the expected results, performance, or achievements expressed or implied by such forward-looking statements. Except as required by law, the Company assumes no obligation to update these forward-looking statements publicly, or to update the reasons actual results could differ materially from those anticipated in the forward-looking statements, even if new information becomes available in the future.

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