ORASURE TECHNOLOGIES INC — Director's Dealing 2012

May 19, 2012

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ORASURE TECHNOLOGIES INC (OSUR)
CIK: 0001116463
Period of Report: 2012-05-16

Reporting Person: KUNA MARK L (SVP & Controller)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2012-05-16	Common stock	M	15175	$5.19	Acquired	65247	Direct
2012-05-16	Common stock	S	15175	$12.066	Disposed	50072	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2012-05-16	Nonqualified stock option	$5.19	M	15175	Disposed	2020-01-25	Common stock (15175)	Direct

Footnotes

F1: Sale pursuant to a predetermined sales plan, entered into on May 31, 2011, under Rule 10b5-1 of the Securities and Exchange Act of 1934.

F2: Nonqualified stock options granted on January 25, 2010 vesting and exercisable over a four year period, with one-fourth of the options vesting on the first anniversary date of the grant and the remainder vesting ratably on a monthly basis, over the remaining 36 months.